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Drug delivery of nitric oxide 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-033/00
  • A61K-033/26
  • A61K-009/02
  • A61K-009/14
출원번호 US-0338664 (1994-11-14)
발명자 / 주소
  • Tawashi Rashad (66 Hyde Park Beaconsfield
  • Quebec CAX H9W 5L8 )
인용정보 피인용 횟수 : 58  인용 특허 : 0

초록 ▼

A method of delivering NO gas to a desired situs on or in the body of a sentient animal, e.g. humans, comprising combining and causing to react a soluble reducing salt, preferably ferrous sulfate, and a nitrite, preferably sodium nitrite, as reactants in the presence of moisture in situ at or adjace

대표청구항

A method of delivering NO gas to a desired situs on or in the body of a sentient animal comprising combining, and causing to react, substantially molecularly equivalent amounts of ferrous sulfate and an organic or inorganic nitrite as reactants with moisture present at or adjacent said situs.

이 특허를 인용한 특허 (58)

  1. Benjamin, Nigel; Dougall, Hamish; Ormerod, Anthony, Acidified nitrite as an antimicrobial agent.
    상세보기
  2. Whitlock, David R.; Jamas, Spiros; Weiss, Larry, Ammonia oxidizing bacteria for treatment of acne.
    상세보기
  3. Whitlock, David R.; Jamas, Spiros; Weiss, Larry, Ammonia oxidizing bacteria for treatment of eczema.
    상세보기
  4. Whitlock, David R., Articles of clothing treated with ammonia oxidizing bacteria to produce nitric oxide.
    상세보기
  5. Fossel, Eric T., Beneficial effects of increasing local blood flow.
    상세보기
  6. Whitlock, David R., Compositions including ammonia oxidizing bacteria to increase production of nitric oxide and nitric oxide precursors and methods of using same.
    상세보기
  7. Fine, David H.; MacDonald, Stephen J.; Rounbehler, David; Wheeler, David; Rolfe, Jonathan L.; Jarvis, George, Controlled generation of nitric oxide.
    상세보기
  8. Fossel, Eric T., Delivery of ibuprofen and other compounds.
    상세보기
  9. Fossel, Eric T., Delivery of ibuprofen and other compounds.
    상세보기
  10. Fossel, Eric T., Delivery of ibuprofen and other compounds.
    상세보기
  11. Stenzler, Alex, Device and method for treatment of surface infections with nitric oxide.
    상세보기
  12. Stenzler, Alex; Miller, Christopher C., Device and method for treatment of surface infections with nitric oxide.
    상세보기
  13. Stenzler, Alex; Miller, Chris C, Device and method for treatment of wounds with nitric oxide.
    상세보기
  14. Beckett, Stephen Thomas; Atkin, Stephen Lawrence; Mackenzie, Grahame, Dosage form.
    상세보기
  15. Trescony,Paul V.; Rohly,Kenneth E.; Keogh,James R.; Untereker,Darrell F.; Istephanous,Naim S., Implantable medical device with controllable gaseous agent release system.
    상세보기
  16. Moskowitz, Michael A.; Liao, James K.; Ron, Eyal S.; Omstead, Mary Nallin, Increasing cerebral bioavailability of drugs.
    상세보기
  17. Stenzler, Alex; Miller, Christopher C.; McMullin, Bevin, Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing.
    상세보기
  18. Montgomery, Frederick J.; Bathe, Duncan P., Method and apparatus for generating nitric oxide for medical use.
    상세보기
  19. Montgomery, Frederick J.; Bathe, Duncan P. L., Method and apparatus for generating nitric oxide for medical use.
    상세보기
  20. Reiss,Carol Shoshkes; Komatsu,Takaishi, Method for increasing the permeability of the blood brain barrier.
    상세보기
  21. Ludwig, Florian Niklas; Pacetti, Stephen; Consigny, Paul, Methods and compositions for treatment of lesioned sites of body vessels.
    상세보기
  22. Ludwig, Florian Niklas; Pacetti, Stephen; Consigny, Paul, Methods and compositions for treatment of lesioned sites of body vessels.
    상세보기
  23. Hassett, Daniel J., Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite.
    상세보기
  24. Miller, J. W. Randolph; Jones, Christie W., Nitric oxide generator and non-deliquescent tablet for use in same.
    상세보기
  25. Miller, J. W. Randolph; Jones, Christie W., Nitric oxide generator and non-deliquescent tablet for use in same.
    상세보기
  26. Miller, J. W. Randolph; Jones, Christie W., Nitric oxide generator and non-deliquescent tablet for use in same.
    상세보기
  27. Jezek, Jan; Watson, Lynne Patricia, Nitric oxide-generating skin dressings.
    상세보기
  28. Kevil, Christopher; Chan, Kyle; Soin, Amol, Pharmaceutical formulations of nitrite and uses thereof.
    상세보기
  29. Miller, J. W. Randolph; Moon, William; Merrell, Keith L., Portable, nitric oxide generator.
    상세보기
  30. Miller, J. W. Randolph; Moon, William; Merrell, Keith L., Portable, nitric oxide generator.
    상세보기
  31. Jezek, Jan; Watson, Lynne Patricia, S-nitrosothiol-generating skin dressings.
    상세보기
  32. Seitz William A. ; Garfield Robert E. ; Balaban Alexandru T. ; Stewart Randall J., Systems and methods for topical treatment with nitric oxide.
    상세보기
  33. Fossel, Eric T., Systems and methods for treatment of allergies and other indications.
    상세보기
  34. Allaker, Robert; Hinds, Charles; Tucker, Arthur Tudor, Therapeutic composition and use.
    상세보기
  35. Fossel, Eric T., Topical composition containing ibuprofen.
    상세보기
  36. Fossel, Eric T., Topical composition containing naproxen.
    상세보기
  37. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
    상세보기
  38. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
    상세보기
  39. Atkin, Stephen Lawrence; Beckett, Stephen Thomas; Mackenzie, Grahame, Topical formulations containing sporopollenin.
    상세보기
  40. Fossel, Eric Thor, Transdermal delivery of beneficial substances effected by a hostile biophysical environment.
    상세보기
  41. Tucker, Arthur T.; Benjamin, Nigel, Transdermal pharmaceutical delivery composition.
    상세보기
  42. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  43. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  44. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  45. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  46. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  47. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  48. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
    상세보기
  49. Gladwin, Mark T.; Schechter, Alan N.; Hunter, Christian J.; Power, Gordon G.; Kim-Shapiro, Daniel B.; Cannon, III, Richard O., Treatment of specific cardiovascular conditions with nitrite.
    상세보기
  50. Miller, Christopher C.; Hole, Douglas R.; Murray, Bruce R; Perry, Bryan, Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant.
    상세보기
  51. Hole, Douglas; Miller, Christopher C., Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma.
    상세보기
  52. Gladwin, Mark T.; Schechter, Alan N.; Lefer, David J.; Patel, Rakesh P.; Hunter, Christian J.; Power, Gordon G.; Kim-Shapiro, Daniel B.; Pluta, Ryszard Marek; Oldfield, Edward H.; Cannon, III, Richard O., Use of nitrite salts for the treatment of cardiovascular conditions.
    상세보기
  53. Gladwin, Mark T.; Schechter, Alan N.; Lefer, David J.; Patel, Rakesh P.; Hunter, Christian J.; Power, Gordon G.; Kim-Shapiro, Daniel B.; Pluta, Ryszard Marek; Oldfield, Edward H.; Cannon, III, Richard O., Use of nitrite salts for the treatment of cardiovascular conditions.
    상세보기
  54. Gladwin, Mark T.; Schechter, Alan N.; Lefer, David J.; Patel, Rakesh P.; Hunter, Christian J.; Power, Gordon G.; Kim-Shapiro, Daniel B.; Pluta, Ryszard; Oldfield, Edward H.; Cannon, III, Richard O., Use of nitrite salts for the treatment of cardiovascular conditions.
    상세보기
  55. Kevil, Christopher; Lefer, David; Patel, Rakesh, Use of nitrite salts in chronic ischemia.
    상세보기
  56. Kevil, Christopher, Use of nitrite salts in treating tissue damage.
    상세보기
  57. Atkin, Stephen Lawrence; Beckett, Stephen Thomas; Mackenzie, Grahame, Uses of sporopollenin.
    상세보기
  58. Atkin, Stephen; Beckett, Stephen; Mackenzie, Grahame, Whitened exine shells.
    상세보기

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