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Prolonged release microparticle preparation and production of the same 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/58
  • A61K-009/62
  • B01J-013/04
출원번호 US-0387392 (1995-02-13)
우선권정보 JP-0253517 (1991-10-01)
발명자 / 주소
  • Takada Shigeyuki (Salt Lake City UT) Uda Yoshiaki (Takarazuka JPX) Ogawa Yasuaki (Kyoto JPX)
출원인 / 주소
  • Takeda Chemical Industries, Ltd. (Osaka JPX 03)
인용정보 피인용 횟수 : 72  인용 특허 : 9

초록 ▼

A novel microparticle preparation comprising microparticles of a polymer which contain a drug and are coated with a film of an agent for preventing aggregation of the microparticles is disclosed. The preparation is produced by spraying a solution of a polymer containing a drug and an aqueous solutio

대표청구항

An injectable microparticle preparation comprising microparticles of a drug-containing polymer coated with a film comprising a water-soluble agent for preventing aggregation of the microparticles, wherein the microparticles have a mean size of about 0.5 m400 m5,000 to 20,000.

이 특허에 인용된 특허 (9)

  1. Benton Ben F. (Centerburg OH) Gardner David L. (Bellville OH), Controlled release liquid dosage formulation.
    상세보기
  2. Wellman Russel E. (Pittsford NY) Brown Robert W. (Rochester NY), Encapsulation process.
    상세보기
  3. Kent John S. (Cupertino CA) Lewis Danny H. (Birmingham AL) Sanders Lynda M. (Palo Alto CA) Tice Thomas R. (Birmingham AL), Microencapsulation of water soluble active polypeptides.
    상세보기
  4. Howard John R. (Merseyside GBX) Delargy Anne M. (Merseyside GBX), Pharmaceutical composition containing high drug load and method for preparing same.
    상세보기
  5. Fujii Jon A. (Davis CA) Redenbaugh Keith (Davis CA) Sakamoto Yuji (Tochigi JPX), Powder coated hydrogel capsules.
    상세보기
  6. Gardner David L. (Bellville OH), Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or e 상세보기
  • Okada Hiroaki (Suita JPX) Ogawa Yasuaki (Ibaraki JPX) Yashiki Takatsuka (Takarazuka JPX), Prolonged release microcapsule and its production.
    상세보기
  • Schmidt Douglass N. (Grosse Ile MI) Finnan Jeffrey L. (Southgate MI) Lisa Rudolph E. (Grosse Ile MI), Spray-dried vitamin powders using hydrophobic silica.
    상세보기
  • Mattei Frank V. (Piscataway NJ) Doddi Namassivaya (Upland CA), Synthetic absorbable hemostatic agent.
    상세보기

    • 이 특허를 인용한 특허 (72)

    1. Persyn, Joseph T.; McDonough, Joseph A.; Vail, Neal K.; Barlow, Darren E.; Zwiener, Albert M.; Slovin, Eliot M., Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates.
      상세보기
    2. Dunn, Richard L; English, James P., Biodegradable polymer composition.
      상세보기
    3. Richard L Dunn ; James P. English, Biodegradable polymer composition.
      상세보기
    4. Song,Young Ho; Welch,Eric D.; Bluni,Scott T., Block copolymer particles.
      상세보기
    5. Bourne, George; Madden, Mike; Madenjian, Art; Rao, Doreen; Buiser, Marcia; Li, Jianmin; Rackley, Raymond; Gellman, Barry N., Bulking agent.
      상세보기
    6. Bourne, George; Madden, Michael; Madenjian, Arthur R.; Rao, Doreen; Buiser, Marcia; Li, Jianmin; Rackley, Raymon; Gellman, Barry N., Bulking agents.
      상세보기
    7. Smith, Thomas J., Coated particles for sustained-release pharmaceutical administration.
      상세보기
    8. Buiser, Marcia S.; Keenan, Steve; Seehusen, Ashley; Nardone, Christopher, Coil assemblies, components and methods.
      상세보기
    9. Hanna, Mazen H.; York, Peter, Compositions of particulate coformulation.
      상세보기
    10. Richard, Robert E., Cross-linked polymer particles.
      상세보기
    11. Platz, Robert M.; Brewer, Thomas K.; Boardman, Terence D., Dispersible macromolecule compositions and methods for their preparation and use.
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    12. Lanphere,Janel L.; McKenna,Erin P.; Naimark,Wendy; Buiser,Marcia S.; Mangin,Stephan P., Drug delivery particle.
      상세보기
    13. Buiser, Marcia S.; Seehusen, Ashley; Nardone, Christopher, Embolic coils.
      상세보기
    14. Elliott, Christopher J.; O'Connor, Patrick G., Embolic coils.
      상세보기
    15. Bell, Barbara; Casey, II, Thomas V.; Shaw, William J., Embolic compositions.
      상세보기
    16. Buiser, Marcia; Bellisario, Marc; Knapp, David; Mangin, Stephan; Lanphere, Janel, Embolization.
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    17. DiCarlo, Paul; Casey, II, Thomas V.; Mangin, Stephan P., Embolization.
      상세보기
    18. Kamath, Kalpana; Freyman, Toby; Mishra, Shubhang, Embolization.
      상세보기
    19. Lanphere, Janel L.; Buiser, Marcia S.; Casey, Thomas V., Embolization.
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    20. Lanphere,Janel; Buiser,Marcia; Casey, II,Thomas V., Embolization.
      상세보기
    21. Rioux, Robert F.; Casey, II, Thomas V.; Lanphere, Janel, Embolization.
      상세보기
    22. Rioux, Robert F.; Casey, II, Thomas V.; Lanphere, Janel L., Embolization.
      상세보기
    23. Lanphere, Janel L.; McKenna, Erin P.; Casey, II, Thomas V., Ferromagnetic particles and methods.
      상세보기
    24. Baldwin,Samuel P.; Skribiski,Robert P., Forming a chemically cross-linked particle of a desired shape and diameter.
      상세보기
    25. Baldwin,Samuel P.; Skribiski,Robert P., Forming a chemically cross-linked particle of a desired shape and diameter.
      상세보기
    26. Baldwin,Samuel P.; Skribiski,Robert P., Forming a chemically cross-linked particle of a desired shape and diameter.
      상세보기
    27. Buiser, Marcia S.; Lee, Elaine, Forming coils.
      상세보기
    28. Sirota, Daniel J., Hemostatic substance with a coating.
      상세보기
    29. Helliwell, James A.; Malone, Amanda M.; Smith, Thomas J.; Baum, Marc M., Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith.
      상세보기
    30. Vaghefi, Farid, Instant water dissolvable encapsulate and process.
      상세보기
    31. Frank P. Zemlan ; Jeffrey Mulchahey, Long acting antidepressant microparticles.
      상세보기
    32. Moyano, Nora; Iturraspe, Jose; Nunez, Jose Lucio, Manufacturing process of microcapsules for sustained release of water soluble peptides.
      상세보기
    33. Castan, Catherine; Meyrueix, Remi; Soula, Gerard, Medicine based on anti-hyperglycaemic microcapsules with prolonged release and method for preparing same.
      상세보기
    34. Benoit Jean-Pierre,FRX ; Rolland Herve,FRX ; Thies Curt,FRX ; Vande Velde Vincent,FRX, Method of coating particles and coated spherical particles.
      상세보기
    35. Jones, David Hugh; Farrar, Graham Henry; Clegg, James Christopher Stephen, Method of making microencapsulated DNA for vaccination and gene therapy.
      상세보기
    36. Tan, Sharon Mi Lyn, Methods and systems for coating particles.
      상세보기
    37. Mulqueen Patrick Joseph,GBX ; Smith Geoff,GBX ; Lubetkin Steven D., Microencapsulation process and product.
      상세보기
    38. Legrand, Valérie; Castan, Catherine; Meyrueix, Rémi; Soula, Gérard, Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles.
      상세보기
    39. Casey, II, Thomas V.; Damiano, Bud, Mixing and delivery of therapeutic compositions.
      상세보기
    40. Castan, Catherine; Guimberteau, Florence; Meyrueix, Rémi, Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s).
      상세보기
    41. Castan, Catherine; Guimberteau, Florence; Meyrueix, Rémi, Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s).
      상세보기
    42. Anderson, Steven M.; Lanphere, Janel, Particles.
      상세보기
    43. DiCarlo, Paul; Lanphere, Janel; Casey, II, Thomas V.; Buiser, Marcia; McKenna, Erin, Particles.
      상세보기
    44. York, Peter; Shekunov, Boris Yu; Rehman, Mahboob Ur; Feeley, Jane Catherine, Particulate materials.
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    45. York, Peter; Shekunov, Boris Yu; Rehman, Mahboob Ur; Feeley, Jane Catherine, Particulate materials.
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    46. York, Peter; Shekunov, Boris Yu; Rehman, Mahboob Ur; Feeley, Jane Catherine, Particulate materials.
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    47. Vehring, Reinhard; Miller, Danforth P.; Lechuga-Ballesteros, David, Pharmaceutical formulation comprising a water-insoluble active agent.
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    48. Vehring, Reinhard; Miller, Danforth P; Lechuga-Ballesteros, David, Pharmaceutical formulation comprising a water-insoluble active agent.
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    49. Lanphere, Janel; St. Pierre, Ernest J.; Kapoglis, Greg; Casey, II, Thomas V., Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient.
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    50. Lanphere,Janel L.; Pierre,Ernest J.; Kapoglis,Greg; Casey, II,Thomas V., Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient.
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    51. Snyder, Herman E.; Nasiatka, James; Varga, Christopher M., Prefilming atomizer.
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    52. Snyder, Herman E; Nasiatka, James; Varga, Christopher M, Prefilming atomizer.
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    53. Shigeyuki Takada,JPX ; Keiko Taira,JPX ; Susumu Iwasa,JPX, Process for producing sustained-release preparation by in-water drying.
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    54. Buiser,Marcia; Baldwin,Samuel P., Processes for manufacturing polymeric microspheres.
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    55. Johal, Sarjit; Pollmeier, Albert J., Salt composition.
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    56. Snyder, Herman E.; Vosberg, Michael J.; Varga, Christopher M., Spray drying methods and related compositions.
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    57. Snyder, Herman E; Vosberg, Michael J; Varga, Christopher M, Spray drying methods and related compositions.
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    58. Bennett, David B.; Brewer, Thomas K.; Platz, Robert M.; Snyder, Herman, Spray drying process control of drying kinetics.
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    59. Bennett, David B; Brewer, Thomas K; Platz, Robert M; Snyder, Herman, Spray drying process control of drying kinetics.
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    60. Dadey, Eric; Zhou, Mingxing, Stabilized polymeric delivery system comprising a water-insoluble polymer and an organic liquid.
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    61. Margaron, Philippe Maria Clotaire; Dadey, Eric; Lindemann, Christopher M.; Li, Ruihong, Sustained delivery formulations of rapamycin compounds.
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    62. Sanghvi,Pradeep P.; Ketsela,Sara, Sustained release formulations of metformin.
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    63. Yamatomo, Kazumichi; Yamada, Akiko; Hata, Yoshio, Sustained-release composition and process for producing the same.
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    64. Gordon, Marc S.; Clark, Andrew; Brewer, Thomas K., Systems and processes for spray drying hydrophobic and hydrophilic components.
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    65. Bourne, George; Buiser, Marcia S.; Casey, II, Thomas V.; Keenan, Steve; Lanphere, Janel L.; Li, Jianmin; McKenna, Erin P.; Minasian, Zarouhi; Rao, Doreen, Tissue treatment.
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    66. Bourne,George; Buiser,Marcia S.; Casey, II,Thomas V.; Keenan,Steve; Lanphere,Janel L.; Li,Jianmin; McKenna,Erin P.; Minasian,Zarouhi; Rao,Doreen, Tissue treatment.
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    67. Lanphere, Janel L.; DiCarlo, Paul; Anderson, Steven M., Tissue-treatment methods.
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    68. Lanphere, Janel L.; DiCarlo, Paul; Anderson, Steven M., Tissue-treatment methods.
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    69. Werner Frantsits AT, Tolperison-containing, pharmaceutical preparation for oral administration.
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    70. Vaghefi, Farid; Lee, Jeffry; Nalamothu, Vijendra, Zero order release and temperature-controlled microcapsules and process for the preparation thereof.
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    71. Gibson, John W.; Tipton, Arthur J.; Holl, Richard J.; Meador, Stacey, Zero-order prolonged release coaxial implants.
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    72. Gibson, John W.; Tipton, Arthur J.; Holl, Richard; Meador, Stacey, Zero-order prolonged release coaxial implants.
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