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Methods and products for nucleic acid delivery 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-047/40
출원번호 US-0675523 (1996-07-03)
발명자 / 주소
  • Isner Jeffrey M. (Weston MA)
출원인 / 주소
  • St. Elizabeth\s Medical Center of Boston, Inc. (Boston MA 02)
인용정보 피인용 횟수 : 76  인용 특허 : 4

초록 ▼

The present invention provides a method for the delivery of a nucleic acid to an arterial cell comprising contacting the cell with a hydrophilic polymer incorporating the nucleic acid. The nucleic acid may be any nucleic acid, including antisense DNA or RNA. The nucleic acid may encode hormones, enz

대표청구항 ▼

A method for inducing the formation of new blood vessels in a desired target tissue in a human host, comprising contacting an arterial cell in an artery or blood vessel via a balloon catheter coated with a hydrogel polymer admixed with a first DNA encoding an angiogenic protein selected from the gro

이 특허에 인용된 특허 (4)

  1. Sahatjian Ronald (Lexington MA), Drug delivery system making use of a hydrogel polymer coating.
    상세보기
  2. Fan You-Ling (East Brunswick NJ), Hydrophilic lubricious coatings.
    상세보기
  3. Srivastava Arun (Indianapolis IN), Safe vector for gene therapy.
    상세보기
  4. Nabel Elizabeth G. (Ann Arbor MI) Nabel Gary J. (Ann Arbor MI), Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor.
    상세보기

이 특허를 인용한 특허 (76)

  1. Crystal Ronald G. ; Magovern Christopher J., Adenoviral-mediated gene transfer to adipocytes.
    상세보기
  2. Nakamura, Toshikazu; Funakoshi, Hiroshi; Miyazawa, Daisuke; Iwatani, Kunio, Agent for treating polyglutamine aggregation-caused disease or suppressing onset thereof.
    상세보기
  3. Ferrara Napoleone ; Isner Jeffrey M. ; Schwall Ralph H., Angiogenesis using hepatocyte growth factor.
    상세보기
  4. Parker Theodore L. ; Joslyn Danforth ; Nikolic Serjan D., Angiogenic implant delivery system and method.
    상세보기
  5. Rosen,Craig A.; Hu,Jing Shan; Cao,Liang, Antibodies to human vascular endothelial growth factor 2.
    상세보기
  6. Rosen, Craig A.; Hu, Jing Shan; Cao, Liang, Antibodies to human vascular endothelial growth factor 2 and methods of using the same.
    상세보기
  7. Hu,Jing Shan; Rosen,Craig A.; Cao,Liang, Antibodies to vascular endothelial growth factor 2 and methods of using same.
    상세보기
  8. Mueller, Richard, Apparatus and method for delivering therapeutic and diagnostic agents.
    상세보기
  9. Mueller,Richard, Apparatus and method for delivering therapeutic and diagnostic agents.
    상세보기
  10. Haim, Shlomo Ben; Yaron, Uri; Matcovitch, Avraham, Apparatus and method for intracardiac therapy using sensor for heart wall thickness.
    상세보기
  11. Oron,Uri; Matcovitch,Avraham, Apparatus for providing electromagnetic biostimulation of tissue using optics and echo imaging.
    상세보기
  12. Barry, James; Palasis, Maria; Ellis, Louis; Mickley, Timothy; Berg, Brian, Biocompatible medical devices.
    상세보기
  13. Kiser, Patrick F.; Thomas, Allen A., Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments.
    상세보기
  14. Laughlin,Mary J.; Haynesworth,Stephen; Pompili,Vincent, Cell-based therapies for ischemia.
    상세보기
  15. Nabel,Gary J.; Yang,Zhi yong; Nabel,Elizabeth G., Combination for site-specifically transforming cells in vivo comprising a double-balloon catheter and nucleic acid comprising a gene encoding P21.
    상세보기
  16. Li, Weiping; Mao, Hai-Quan; Leong, Kam W., Controlled delivery of therapeutic agents by insertable medical devices.
    상세보기
  17. Chee, U. Hiram; Meuller, Richard, Devices and methods for delivering a drug.
    상세보기
  18. Wolff, Jon A.; Duke, David J.; Felgner, Philip L., Expression of exogenous polynucleotide sequences in a vertebrate.
    상세보기
  19. Andrew Baird ; Grai Andreason, Forms of the angiogenic factor vascular endothelial cell growth factor: VEGF.
    상세보기
  20. John H. Lawrence, III ; J. Kevin Donahue, Gene delivery compositions and methods.
    상세보기
  21. Lawrence, III,John H.; Donahue,J. Kevin, Gene delivery compositions and methods.
    상세보기
  22. Hammond H. Kirk ; Giordano Frank J. ; Dillmann Wolfgang H., Gene therapies for enhancing cardiac function.
    상세보기
  23. Hammond H. Kirk ; Giordano Frank J. ; Dillmann Wolfgang H., Gene therapies for enhancing cardiac function.
    상세보기
  24. Morishita,Ryuichi; Taniyama,Yoshiaki; Ogihara,Toshio, Gene therapy for cardiomyopathy.
    상세보기
  25. Morishita, Ryuichi; Ogihara, Toshio, Gene therapy for cerebrovascular disorders.
    상세보기
  26. Maria Palasis ; Kenneth Walsh, High efficiency local drug delivery.
    상세보기
  27. Kim, Jong-Mook; Hahn, Woong, Hybrid hepatocyte growth factor gene having high expression efficiency of two heterotypes of hepatocyte growth factor.
    상세보기
  28. Kim, Jong-Mook; Hahn, Woong, Hybrid hepatocyte growth factor gene having high expression efficiency of two heterotypes of hepatocyte growth factor.
    상세보기
  29. Kim, Jong-Mook; Hahn, Woong; Park, Eun-Jin, Hybrid hepatocyte growth factor gene having high expression efficiency of two heterotypes of hepatocyte growth factor.
    상세보기
  30. Forman, Michael Robert; Bobo, Jr., Donald E., Intra-pericardial drug delivery device with multiple balloons and method for angiogenesis.
    상세보기
  31. Haim Shlomo Ben,ILX ; Yaron Uri,ILX ; Matcovitch Avraham,ILX, Intracardiac drug delivery.
    상세보기
  32. Haim Shlomo Ben,ILX ; Yaron Uri,ILX ; Matcovitch Avraham,ILX, Intracardiac drug delivery device utilizing spring-loaded mechanism.
    상세보기
  33. Kaplan Aaron V. ; Simons Michael, Localized intravascular delivery of growth factors for promotion of angiogenesis.
    상세보기
  34. Morishita Ryuichi,JPX ; Ogihara Toshio,JPX ; Nakamura Toshikazu,JPX ; Tomita Tetsuya,JPX ; Ochi Takahiro,JPX, Medicament comprising HGF gene.
    상세보기
  35. Morishita,Ryuichi; Ogihara,Toshio; Nakamura,Toshikazu; Tomita,Tetsuya; Ochi,Takahiro, Medicament comprising HGF gene.
    상세보기
  36. Chee,U. Hiram; Mueller,Richard L.; Kermode,James R.; Tom,Curtis P.; Murphy Chutorian,Douglas, Method and apparatus for treatment of atrial fibrillation.
    상세보기
  37. Lee, Myoung Woo; Kim, Young Jin; Choi, Jeong Eun; Yang, Mal Sook; Moon, Young Joon; Kim, Sun Kyung; Kim, Hugh Chul; Park, Joon Seong; Jang, In Keun, Method for isolating and culturing multipotent progenitor cells from umbilical cord blood.
    상세보기
  38. Ben-Haim, Shlomo; Fenster, Maier, Method for treating tissue through injection of a therapeutic agent.
    상세보기
  39. Parker Theodore L. ; Joslyn Danforth ; Nikolic Serjan D., Method of enhancing blood flow in tissue.
    상세보기
  40. Crystal, Ronald G.; Hidaka, Chisa; Boachie-Adjei, Oheneba; Rawlins, Bernard A.; Kovesdi, Imre, Method of enhancing bone density.
    상세보기
  41. Elia, James P., Method of growing an artery.
    상세보기
  42. Uri Oron IL; Avraham Matcovitch IL, Method of treating a heart using cells irradiated in vitro with biostimulatory irradiation.
    상세보기
  43. Nakamura Toshikazu,JPX ; Komamura Kazuo,JPX ; Miyatake Kunio,JPX, Method of treating dilated cardiomyopathy.
    상세보기
  44. Bunting Stuart ; Gold Herman K. ; Leinbach Robert C. ; Schwall Ralph H., Methods and compositions for treating vascular stenosis.
    상세보기
  45. Isner Jeffrey M. ; Asahara Takayuki, Methods for enhancing angiogenesis with endothelial progenitor cells.
    상세보기
  46. Dzau, Victor J.; Pratt, Richard E.; Mann, Michael J.; Ehsan, Afshin; Griese, Daniel P., Methods for implanting cells.
    상세보기
  47. Victor J. Dzau ; Richard E. Pratt ; Michael J. Mann ; Afshin Ehsan ; Daniel P. Griese, Methods for implanting cells.
    상세보기
  48. Hu,Jing Shan; Rosen,Craig A.; Cao,Liang, Methods of stimulating angiogenesis in a patient by administering vascular endothelial growth factor 2.
    상세보기
  49. Alderson, Ralph; Melder, Robert; Roschke, Viktor; Ruben, Steven M.; Rosen, Craig A., Methods of treating an injury to, or disorder of, the eye involving photoreceptor proliferation by administering VEGF2 antibodies.
    상세보기
  50. Chee, U. Hiram; Mueller, Richard L.; Kermode, James R.; Tom, Curtis P.; Murphy-Chutorian, Douglas, Methods of treating cardiac arrhythmia.
    상세보기
  51. Forman, Michael Robert, Multi-balloon drug delivery catheter for angiogenesis.
    상세보기
  52. Forman,Michael Robert, Multi-balloon drug delivery catheter for angiogenesis.
    상세보기
  53. Rosen,Craig A.; Hu,Jing Shan; Cao,Liang, Polynucleotides encoding human vascular endothelial growth factor 2.
    상세보기
  54. Shi Rui-wen,CNX ; Gao Run-lin,CNX, Protein-coated medical substrates for local delivery of genes and method of forming coatings on the substrates.
    상세보기
  55. Rashtchian, Ayoub; Solus, Joseph, Stable compositions for nucleic acid amplification and sequencing.
    상세보기
  56. Wolff Jon A. ; Duke David J. ; Felgner Philip L., Stimulating vascular growth by administration of DNA sequences encoding VEGF.
    상세보기
  57. Roth, Laurence A.; Herman, Stephen Jack, Targeted delivery via biodegradable polymers.
    상세보기
  58. McBride,James F.; Gehrke,Stevin H.; Fisher,John P., Temperature controlled solute delivery system.
    상세보기
  59. Michal Eugene T. ; Buchko Christopher J. ; Bigus Stephen J., Therapeutic, diagnostic, or hydrophilic coating for an intracorporeal medical device.
    상세보기
  60. Fick James R., Tumor delivery vehicles.
    상세보기
  61. James R. Fick, Tumor delivery vehicles.
    상세보기
  62. Alitalo, Kari; Yl?-Herttuala, Seppo; Hiltunen, Mikko O.; Jeltsch, Markku M.; Achen, Marc G., Use of VEGF-C to prevent restenosis.
    상세보기
  63. Alitalo, Kari; Ylä-Herttuala, Seppo; Hiltunen, Mikko O.; Jeltsch, Markku M.; Achen, Marc G., Use of VEGF-D gene to prevent restenosis.
    상세보기
  64. Alderson,Ralph; Melder,Robert; Roschke,Viktor; Ruben,Steven M.; Rosen,Craig A., Use of vascular endothelial growth factor to treat photoreceptor cells.
    상세보기
  65. Neufeld Gera,ILX ; Keshet Eli,ILX ; Vlodavsky Israel,ILX ; Poltorak Zoya,ILX, VEGF.sub.145 expression vectors.
    상세보기
  66. Hu,Jing Shan; Rosen,Craig A.; Cao,Liang, Vascular endothelial growth factor 2.
    상세보기
  67. Hu,Jing Shan; Rosen,Craig A.; Cao,Liang, Vascular endothelial growth factor 2.
    상세보기
  68. Hu,Jing Shan; Rosen,Craig A.; Cao,Liang, Vascular endothelial growth factor 2.
    상세보기
  69. Rosen, Craig A.; Albert, Vivian R.; Ruben, Steven M.; Wager, Ruth, Vascular endothelial growth factor 2.
    상세보기
  70. Rosen, Craig A.; Albert, Vivian R.; Ruben, Steven M.; Wager, Ruth E., Vascular endothelial growth factor 2.
    상세보기
  71. Rosen, Craig A.; Albert, Vivian R.; Ruben, Steven M.; Wager, Ruth E., Vascular endothelial growth factor 2.
    상세보기
  72. Rosen, Craig; Albert, Vivian; Ruben, Steven M.; Wager, Ruth, Vascular endothelial growth factor 2.
    상세보기
  73. Rosen, Craig; Albert, Vivian; Ruben, Steven M.; Wager, Ruth, Vascular endothelial growth factor 2.
    상세보기
  74. Rosen,Craig A.; Albert,Vivian R.; Ruben,Steven M.; Wager,Ruth E., Vascular endothelial growth factor 2.
    상세보기
  75. Hu,Jing Shan; Rosen,Craig A.; Cao,Liang, Vascular endothelial growth factor 2 and methods of use.
    상세보기
  76. Coleman,Timothy A., Vascular endothelial growth factor-2.
    상세보기

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