[특허]Test device for detecting analytes in biological samples

Test device for detecting analytes in biological samples 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	G01N-033/558
출원번호	US-0305967 (1994-09-15)
우선권정보	GB-0009873 (1987-04-27); GB-0025457 (1987-10-30); WOGB-00322 (1988-04-26)
발명자 / 주소	May Keith (Bedfordshire GB2) Prior Michael Evans (Northamptonshire GB2) Richards Ian (Bedford GB2)
출원인 / 주소	Unilever Patent Holdings B.V. (NLX 03)
인용정보	피인용 횟수 : 224 인용 특허 : 0

초록 ▼

An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with the exterior of the casing via a bibulous sample receiving member (506) which protrudes from the casing such that a liquid test sample can be applied to the receiving member and permeate therefrom to the porous carrier, the carrier containing in a first zone a labelled specific binding reagent is freely mobile within the porous carrier when in the moist state, wherein the mobility is facilitated by a material comprising a sugar, in an amount effective to reduce interaction between the test strip and the labelled reagent, and in a second zone spatially distinct from the first zone unlabelled specific binding reagent for the same analyte which unlabelled reagent is permanently immobilised on the carrier material and is therefore not mobile in the moist state, the two zones being arranged such that liquid sample applied to the porous carrier can permeate via the first zone into the second zone, and the device incorporating means, such as an aperture (508) in the casing, enabling the extent (if any) to which the labelled reagent becomes bound in the second zone to be observed. Preferably the device includes a removable cap for the protruding bibulous member.

대표청구항 ▼

An analytical test device for detecting an analyte suspected of being present in a liquid biological sample selected from the group consisting of urine and serum, said device comprising: a) a hollow casing having a liquid biological sample application aperture and a test result observation aperture; b) a bibulous liquid biological sample receiving member within said hollow casing to receive said liquid biological sample applied to said sample application aperture; c) a test strip comprising a dry porous carrier within said casing and extending from said bibulous liquid biological sample receiving member to and beyond said test result observation aperture, said dry porous carrier having a test result zone observable through said observation aperture; at least one of said bibulous liquid biological sample receiving member and said test strip containing upstream from said test result zone a labelled reagent capable of specifically binding with said analyte to form a first complex of said labelled reagent and said analyte; said label being a particulate direct label wherein said labelled reagent is dry on said test strip prior to use and is released into mobile form by said liquid biological sample, wherein mobility of said labelled reagent within said test strip is facilitated by at least one of 1) coating at least a portion of said test strip upstream from said test result zone with, or 2) drying said labelled reagent onto a portion of said test strip upstream from said test zone in the presence of, a material comprising sugar, in an amount effective to reduce interaction between said test strip and said labelled reagent; said dry porous carrier containing in said test result zone a means for binding said first complex, said means for binding comprising specific binding means and being immobilized in said test result zone; migration of said liquid biological sample from said bibulous sample receiving member into and through said dry porous carrier conveying by capillarity said first complex to said test result zone of said dry porous carrier whereat said binding means binds said first complex thereby to form a second complex; said second complex being observable through said test result observation aperture, thereby to indicate the present of said analyte in said liquid biological sample.

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Anderson, Emory V.; Lapointe, Jerome; Martinez, Ricardo; Marzolf, Gail; Pong, Ronald; Jones, Lynn; Hussa, Robert O.; Nemec, Edward; Senyei, Andrew E.; DeSieno, Duane, Point of care diagnostic systems.
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Anderson,Emory V.; Nemec,Edward; Lapointe,Jerome P.; DeSieno,Duane; Martinez,Ricardo R.; Marzolf,Gail; Pong,Ronald; Jones,Lynn; Hussa,Robert; Senyei,Andrew, Point of care diagnostic systems.
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Emory V. Anderson ; Jerome Lapointe ; Ricardo Martinez ; Gail Marzolf ; Ronald Pong ; Lynn Jones ; Robert O. Hussa ; Edward Nemec ; Andrew E. Senyei ; Duane DeSieno, Point of care diagnostic systems.
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Song, Xuedong; Wei, Ning; Sayre, Curt, Polyelectrolytic internal calibration system of a flow-through assay.
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Song, Xuedong; Wei, Ning; Sayre, Curtis N., Polyelectrolytic internal calibration system of a flow-through assay.
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Bauer, Jeffrey S.; Hyatt, Timothy P.; Wang, Huiying, Positive detection lateral-flow apparatus and method for small and large analytes.
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Bauer, Jeffrey S.; Hyatt, Timothy P.; Wang, Huiying; Buck, Robert L., Positive detection lateral-flow apparatus and method for small and large analytes.
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Colgin, Mark; Newman, Diane; Landmann, Cathy; Roth, Jay W.; Hurst, Roger; Hansen, Thomas R.; Austin, Kathleen Jeanette, Pregnancy detection.
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Wang, Naishu; Zhou, David F., Progressive compression driven flow cartridge for analyte detecting strip and method.
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Wang, Naishu; Chang Chien, Michael, Rapid diagnostic test device by driven flow technology.
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Wang, Naishu; Chang Chien, Michael, Rapid diagnostic test device by driven flow technology.
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Wang, Naishu; Chang Chien, Michael, Rapid diagnostic test device by driven flow technology.
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Wang, Daniel, Rapid lateral flow assay method for low quantity liquid or dry samples.
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Tung, Hsiaoho E.; Wu, Yuzhang; Dai, Jeilin; Yang, Ying, Rapid sample collection and analysis device and methods of use.
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Liang, Greg; Liang, Yahong, Rapid test apparatus.
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Breidenthal, Scott S.; Kacian, Daniel L.; Lee, Richard S.; Nelson, Norman C.; Scott, Matthew J.; Taylor, Jason A., Receptacles for storing substances in different physical states.
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Esfandiari, Javanbakhsh, Reduced step dual path immunoassay device and method.
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Niedbala, R. Sam; Scott, John W.; Bourdelle, Peter A.; Feindt, Hans H., Sample collector and test device.
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Niedbala, R. Sam; Scott, John W.; Bourdelle, Peter A.; Feindt, Hans H., Sample collector and test device.
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Battrell, C. Frederick; Sprague, Isaac; Bragd, Matthew Scott; Capodanno, Jason, Sample-to-answer microfluidic cartridge.
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Song,Xuedong; Kaylor,Rosann, Self-calibration system for a magnetic binding assay.
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Fong, Whalley K., Sensitive immunochromatographic assay.
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Fong,Whalley K., Sensitive immunochromatographic assay.
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Yao, Kai Ling; Chun, Peter, Sequential solid phase immunoassay including contact pad to limit conjugate flow during manufacture.
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Buck Robert L., Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules.
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Mao,Guoqiang; Coppola,Richard J.; Greene,George Warren; Yao,George, Sintered polymer membrane for analyte detection device.
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DiPerna, Paul M., Slideable flow metering devices and related methods.
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Brown, David, Solute concentration measurement device and related methods.
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Ramsey, James T.; Hartselle, Larry, Specimen collection and assay container.
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Ramsey, James T.; Hartselle, Larry, Specimen collection and assay container.
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Ramsey, James T.; Hartselle, Larry, Specimen collection and assay container.
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Hudak,Robert Thomas, Specimen collection container.
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Hudak,Robert Thomas; Guan,Zhumin; Wu,Yuchang; Yang,Ying, Specimen collection container.
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Rosinko, Michael J.; Kruse, Geoffrey A.; Harris, Paul, System and method for detecting occlusions in an infusion pump.
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Metzmaker, Thomas; Saint, Sean; Michaud, Michael; Rosinko, Michael J.; Swanson, Vance, Systems including vial adapter for fluid transfer.
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Charlton David E. ; Miller Neal W., Test device and method for colored particle immunoassay.
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David E. Charlton, Test device and method for colored particle immunoassay.
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Bagaria,Padma S., Test device for detecting human blood and method of use.
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Catt, Michael; Lenko, Peter; Pearson, Michael T., Test kits and devices.
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Catt, Michael; Lenko, Peter; Pearson, Michael T., Test kits and devices.
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McMenamy, Jim; Lin, James Feng, Test platform.
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Fernandez Decastro, Aurora L., Test strip for simultaneous detection of a plurality of analytes.
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Freedman,Jon; Spano,William; Gupta,Deepti S., Thermoplastic composition comprising a COreleasing material.
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DiPerna, Paul M., Two chamber pumps and related methods.
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Rundström, Gerd; Matsson, Per; Christopher, Paul, Two step lateral flow assay methods and devices.
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Rundström, Gerd; Matsson, Per; Christopher, Paul, Two step lateral flow assay methods and devices.
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Hudak, Robert; Buchanan, Ian, Use of non-chelated fluorochromes in rapid test systems.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

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Test device for detecting analytes in biological samples 원문보기

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연합인증

Test device for detecting analytes in biological samples 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

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이 특허를 인용한 특허 (224)

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