초록 ▼

A device for administering an active agent to the skin or mucosa of an individual comprising a laminated composite of an adhesive overlay, a backing layer underlying the central portion of the adhesive overlay, an active agent-permeable membrane, the backing layer and membrane defining a reservoir t

A device for administering an active agent to the skin or mucosa of an individual comprising a laminated composite of an adhesive overlay, a backing layer underlying the central portion of the adhesive overlay, an active agent-permeable membrane, the backing layer and membrane defining a reservoir that contains a formulation of the active agent, a peel seal disc underlying the active agent-permeable membrane, a heat seal about the periphery of the peel seal disc, the active agent-permeable membrane and the backing layer and a removable release liner underlying the exposed overlay and peel seal disc. The adhesive layer is above and peripheral to the path of the active agent to the skin or mucosa and is protected from degradation by the components of the reservoir by a multiplicity of heat seals. The peel seal disc protects against release of the active agent-containing reservoir and the release liner protects the adhesive from exposure to the environment prior to use.

대표청구항 ▼

A device for administering an active agent to the skin or mucosa of an individual comprising a laminated composite of: (a) a backing layer defining an upper portion of a reservoir and extending to the periphery of a peel seal disk; (b) an active agent-permeable membrane extending to the periphery of

A device for administering an active agent to the skin or mucosa of an individual comprising a laminated composite of: (a) a backing layer defining an upper portion of a reservoir and extending to the periphery of a peel seal disk; (b) an active agent-permeable membrane extending to the periphery of the peel seal disk and the backing layer, and underlying the backing layer, the backing layer and membrane defining (c) the reservoir therebetween that contains a formulation of the active agent; (d) the peel seal disc underlying an active agent-permeable membrane; (e) a heat seal about the periphery of the peel seal disc, the active agent-permeable membrane and the backing layer; (f) an adhesive overlay having a central portion overlying the backing layer and a peripheral portion that extends beyond the periphery of the peel seal disc; and (g) a removable release liner underlying the peripheral portion of the adhesive overlay and the peel seal disc.