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Process for rapid and ultrasensitive detection and counting of microorganisms by fluorescence

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-033/53
  • G01N-033/00
  • C12N-011/00
  • C12N-011/16
출원번호 US-0493130 (1995-06-21)
우선권정보 EP-0402610 (1994-11-17)
발명자 / 주소
  • Drocourt Jean-Louis (Yerres FRX) Desfetes Patrick (Saint Brice Sous Foret FRX) Sanghera Jaspal (Foxton GBX)
출원인 / 주소
  • Chemunex (Maisons-Alfort FRX 03)
인용정보 피인용 횟수 : 36  인용 특허 : 9

초록

Process for rapid, ultrasensitive and automatic counting of fluorescent biological cells such as microorganims, carried by a solid support such as a filter. The process includes: scanning a solid support on which a specimen potentially containing microorganisms has been deposited, with an incident b

대표청구항

Method for detecting and counting separated fluorescent microorganisms arrayed in two dimensions on a solid support and spaced apart by a distance greater than a diameter of an incident laser beam, comprising the steps of: scanning said solid support on which a specimen potentially containing microo

이 특허에 인용된 특허 (9)

  1. Ogino Shinichi (Nishiku JPX) Kosaka Tokihiro (Kakogawashi JPX), Apparatus for analyzing particle images.
  2. Douglas-Hamilton Diarmaid H. (Beverly MA) Loomis Paul R. (Groveland MA) Boisseau Paul (Waltham MA) Nett William P. (Waltham MA), Fluorescence and motility characterization system for cells, bacteria, and particles in fluids.
  3. Kamentsky Louis A. (Weston MA), Generalized cytometry instrument and methods of use.
  4. Morton Roger R. A. (Penfield NY) McCarthy Cornelius J. D. (Fairport NY), Image analysis data extraction.
  5. Conrad Morgan P. (Mountain View CA) Reichert Thomas A. (Los Altos CA) Bezdek James C. (Lexington SC), Method of displaying multi-parameter data sets to aid in the analysis of data characteristics.
  6. Recktenwald Diether J. (Cupertino CA) Chen Chia H. (San Jose CA), Multi-color fluorescence analysis with single wavelength excitation.
  7. Berglund C. Neil (Oregon City OR) Thomas John R. (Oakland CA) Poreda John T. (Moraga CA), Multiphase printing for E-beam lithography.
  8. Delaage Michel (Bouches-du-Rhone FRX) Drocourt Jean-Louis (Bouches-du-Rhone FRX) Hirn Jelle (Bouches-du-Rhone FRX) van Agthoven Andras (Bouches-du-Rhone FRX), Products for separation applicable to cells in the immunopurification field.
  9. Jaggi Bruno (2180 Trafalgar Street Vancouver ; British Columbia CAX V6K 4M8) Deen Mohammed J. (School of Engineering Design ; Simon Fraser Univ. Burnaby ; B.C. CAX V5A 1S6) Palcic Branko (6012 Adera , Quantitative light microscope using a solid state detector in the primary image plane.

이 특허를 인용한 특허 (36)

  1. Bachelet, Ido; Pollak, Joseph Joel; Levner, Daniel; Bilu, Yonatan; Yorav-Raphael, Noam, Apparatus and method for automatic detection of pathogens.
  2. Bangert, Joachim; Friedrich, Katja; Gumbrecht, Walter; Hiltawsky, Karsten; Paulicka, Peter; Stanzel, Manfred, Arrangement and process for optical analysis and specific isolation of biological samples.
  3. King,Frederick David, Automatic identification of suspended particles.
  4. Browne, Douglas; Straus, Don; Mace, Chad, Cassette containing growth medium.
  5. Aviles, Robert C.; Michaud, Devin T.; Browne, Douglas J., Cassette for sterility testing.
  6. Cassells, John, Chemical and biochemical assay method and apparatus.
  7. Groner Warren ; Sanghera Jaspal,GBX ; Desfetes Patrick,FRX, Digital flow cytometer and method.
  8. Stimpson, Eric, Fluorescence-based viability staining method using a membrane permeable flourescent dye and membrane impermeable fluorescence quencher.
  9. Babico, John Y.; Jiang, Jian-Ping, Integrated microbial collector.
  10. Hansen, Frans Ejner Ravn; Glensbjerg, Martin; Arnvidarson, Borkur; Jeppesen, Jesper Myron, Method and a system for determination of particles in a liquid sample.
  11. Hansen, Frans Ejner Ravn; Glensbjerg, Martin; Arnvidarson, Borkur; Jeppesen, Jesper Myron, Method and a system for determination of particles in a liquid sample.
  12. Hansen, Frans Ejner Ravn; Glensbjerg, Martin; Arnvidarson, Börkur; Jeppesen, Jesper Myron, Method and a system for determination of particles in a liquid sample.
  13. Hansen, Frans Ejner Rvan; Glensbjerg, Martin; Arnvidarson, Borkur; Jeppesen, Jesper Myron, Method and a system for determination of particles in a liquid sample.
  14. Hansen, Frans Ejner Rvan; Glensbjerg, Martin; Arnvidarson, Borkur; Jeppesen, Jesper Myron, Method and a system for determination of particles in a liquid sample.
  15. Hansen,Frans; Glensbjerg,Martin; Arnvidarson,Borkur; Jeppesen,Jesper Myron, Method and a system for determination of particles in a liquid sample.
  16. Hansen, Frans Ejner Rvan; Glensbjerg, Martin; Arnvidarson, Borkur; Jeppesen, Jesper Myron, Method and a system for determination of somatic cells in milk.
  17. Hansen, Frans Ejner Rvan; Glensbjerg, Martin; Arnvidarson, Borkur; Jeppesen, Jesper Myron, Method and a system for determination of somatic cells in milk.
  18. Stallinga, Sjoerd; Cattaneo, Stefano, Method and apparatus for rapid filter analysis of fluid samples.
  19. Abrams, Ezra; Gite, Sadanand; Shinefeld, Lisa; Straus, Don; Siek, Gordon; Yantz, Greg, Method for detecting analytes.
  20. Hyman, Jones M.; Walsh, John D.; Thorpe, Thurman C., Method for the characterization of microorganisms on solid or semi-solid media.
  21. King Chester F. ; Hallowitz Robert A., Method of and apparatus for automating detection of microorganisms.
  22. Stimpson, Eric, Method of viability staining with membrane permeable fluorescent dye and membrane impermeable fluorescence quencher.
  23. Perner, Petra, Methods for automatically identifying microorganisms collected on a carrier.
  24. Hyman, Jones; Walsh, John; Thorpe, Thurman, Methods for the characterization of microorganisms on solid or semi-solid media.
  25. Hyman, Jones; Walsh, John; Thorpe, Thurman, Methods for the characterization of microorganisms on solid or semi-solid media.
  26. Bewersdorf, Joerg; Gugel, Hilmar, Microscope and method for operating a microscope.
  27. Wainwright, Norman R.; Manian, Bala S.; Stimpson, Eric; Kolonia, Brian J.; Kolonia, Robert K., Optical method for detecting viable microorganisms in a cell sample.
  28. Straus, Don, Rapid and sensitive detection of cells and viruses.
  29. Straus, Don, Rapid and sensitive detection of molecules.
  30. .O slashed.fjord Gro,NOX ; Skj.ang.nes Kari,NOX ; Aalen Nina,NOX ; Berg James D.,NOX, Rapid coliform detection system.
  31. .O slashed.fjord Gro,NOX ; Skj.ang.nes Kari,NOX ; Aalen Nina,NOX ; Berg James D.,NOX, Rapid coliform detection system.
  32. Tryland, Ingun; Berg, James D.; Skjanes, Kari, Rapid coliform detection system.
  33. Straus, Don, Rapid detection of replicating cells.
  34. Straus, Don, Rapid detection of replicating cells.
  35. Straus, Don, Rapid detection of replicating cells.
  36. Bentien, Anders, Sensor system for detecting and specifying individual particles in a fluid.
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