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Preparation of peptide containing biodegradable microspheres by melt process 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B01J-013/02
  • B05D-007/00
출원번호 US-0547962 (1995-10-25)
발명자 / 주소
  • Cha Younsik (Salt Lake City UT) Choi Young Kweon (Salt Lake City UT) Pai Chaul Min (Taejon KRX)
출원인 / 주소
  • Macromed, Inc. (Salt Lake City UT 02)
인용정보 피인용 횟수 : 107  인용 특허 : 0

초록 ▼

Peptide/protein biodegradable drug delivery devices are prepared as microspheres without the use of solvents by a polymer melt process. A melt of thermostable polypeptides and an appropriate low melting block copolymer mixture is prepared and dispersed in an appropriate fluid medium such as air, wat

대표청구항 ▼

A process for preparing microspheres of an admixture of a biodegradable low melting point block copolymer and a water soluble and heat resistant peptide/protein drug, which comprises: (a) preparing a molten mixture of an effective amount of peptide/protein drug microparticles and a biodegradable blo

이 특허를 인용한 특허 (107)

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  2. Ballard, Robert L.; Anneaux, Bruce L.; Manasco, Joshua L., Antimicrobial substrate.
    상세보기
  3. Persyn,Joseph T.; McDonough,Joseph A.; Vail,Neal K.; Barlow,Darren E.; Zwiener,Albert M.; Slovin,Eliot M., Apparatus for preparing biodegradable microparticle formulations containing pharmaceutically active agents.
    상세보기
  4. Cottone, Robert J., Bioabsorbable medical device with coating.
    상세보기
  5. Cottone, Robert J.; Thatcher, G. Lawrence, Bioabsorbable polymeric composition and medical device.
    상세보기
  6. Thatcher, G. Lawrence; Cottone, Robert J., Bioabsorbable polymeric composition for a medical device.
    상세보기
  7. Shih, Chung; Zentner, Gaylen, Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles.
    상세보기
  8. Kiser, Patrick F.; Thomas, Allen A., Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments.
    상세보기
  9. Persyn, Joseph T.; McDonough, Joseph A.; Vail, Neal K.; Barlow, Darren E.; Zwiener, Albert M.; Slovin, Eliot M., Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates.
    상세보기
  10. Pacetti, Stephen D.; Trollsas, Mikael, Biodegradable triblock copolymers for implantable devices.
    상세보기
  11. Pacetti, Stephen D.; Trollsas, O. Mikael, Biodegradable triblock copolymers for implantable devices.
    상세보기
  12. Barnett, Christian; Ashton, Paul; Canham, Leigh T., Bioerodible silicon-based compositions for delivery of therapeutic agents.
    상세보기
  13. Barnett, Christian; Ashton, Paul; Canham, Leigh T., Bioerodible silicon-based compositions for delivery of therapeutic agents.
    상세보기
  14. Ashton, Paul; Canham, Leigh T.; Barnett, Christian, Bioerodible silicon-based devices for delivery of therapeutic agents.
    상세보기
  15. Ashton, Paul; Canham, Leigh T.; Barnett, Christian, Bioerodible silicon-based devices for delivery of therapeutic agents.
    상세보기
  16. Ornberg,Richard; Udipi,Kishore; Forster,Denis; Riley,Dennis; Thurmond,Bruce; Henke,Susan; Brethauer,Kerry, Biomaterials modified with superoxide dismutase mimics.
    상세보기
  17. Masters, David B.; Berg, Eric Peter, Biomatrix structural containment and fixation systems and methods of use thereof.
    상세보기
  18. Ornberg,Richard L.; Udipi,Kishore; Forster,Denis; Riley,Dennis P.; Thurmond,Kenneth B.; Henke,Susan; Brethaur,Kerry; Joardar,Saikat, Biopolymers modified with superoxide dismutase mimics.
    상세보기
  19. Puckett, Sabrina D.; Manasco, Joshua; Ballard, Robert L.; Anneaux, Bruce L., Composite prosthetic devices.
    상세보기
  20. Byun, Young-Ro; Kim, Sang-Yoon; Kim, Sun-Hee; Choi, Yong-Doo; Han, In-Suk; Lee, Kwang-Sun; Kim, Chul-Hee, Controlled drug release system of retinoic acid.
    상세보기
  21. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakis, Nick, Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes.
    상세보기
  22. David B. Masters, Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices.
    상세보기
  23. Siegel, Steven; Winey, Karen, Drug-containing PLA implants and methods of use thereof.
    상세보기
  24. Siegel, Steven; Winey, Karen, Drug-containing implants and methods of use thereof.
    상세보기
  25. Siegel, Steven; Winey, Karen, Drug-containing implants and methods of use thereof.
    상세보기
  26. Siegel, Steven; Winey, Karen, Drug-containing implants and methods of use thereof.
    상세보기
  27. Siegel, Steven; Winey, Karen, Drug-containing implants and methods of use thereof.
    상세보기
  28. Hall, John William; Simmons, Rachel L.; Hopkinson, Aaron; Dolmatch, Bart; Eller, Zeke; Kellar, Robert S., Drug-eluting rotational spun coatings and methods of use.
    상세보기
  29. Young, Janel E.; Wadsworth, Scott A.; Cooper, Kevin; Rosenblatt, Joel; Cui, Han, Drug-enhanced adhesion prevention.
    상세보기
  30. Young, Janel E.; Wadsworth, Scott A.; Cooper, Kevin; Rosenblatt, Joel; Cui, Han, Drug-enhanced adhesion prevention.
    상세보기
  31. Young, Janel E.; Wadsworth, Scott A.; Cooper, Kevin; Rosenblatt, Joel; Cui, Han, Drug-enhanced adhesion prevention.
    상세보기
  32. Anneaux, Bruce L.; Ballard, Robert L.; Garner, David P., Electrospinning of PTFE.
    상세보기
  33. Masters, David B.; Berg, Eric P., Encapsulated or coated stent systems.
    상세보기
  34. Canham, Leigh T.; Barrett, Christopher P.; Cox, Timothy I.; Wright, Peter J.; Bowditch, Andrew P., Implants for administering substances and methods of producing implants.
    상세보기
  35. Bucha, Elke; Nowak, G?tz, Interactive system for presenting and eliminating substances.
    상세보기
  36. Bucha,Elke; Nowak,G��tz, Interactive system for presenting and eliminating substances.
    상세보기
  37. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D., Macromolecular microparticles and methods of production and use.
    상세보기
  38. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J., Macromolecular microparticles and methods of production and use.
    상세보기
  39. Woiszwillo James E. ; Brown Larry R. ; Scott Terrence L. ; Di Jie ; Sudhalter Judith ; Blizzard Charles D. ; Riske Frank J., Macromolecular microparticles and methods of production and use.
    상세보기
  40. Aviv, Moran; Buzhansky, Ludmila; Einav, Shmuel; Nevo, Zvi; Gazit, Ehud; Adler-Abramovich, Lihi, Malleable hydrogel hybrids made of self-assembled peptides and biocompatible polymers and uses thereof.
    상세보기
  41. Aviv, Moran; Buzhansky, Ludmila; Einav, Shmuel; Nevo, Zvi; Gazit, Ehud; Adler-Abramovich, Lihi, Malleable hydrogel hybrids made of self-assembled peptides and biocompatible polymers and uses thereof.
    상세보기
  42. Aviv, Moran; Buzhansky, Ludmila; Einav, Shmuel; Nevo, Zvi; Gazit, Ehud; Adler-Abramovich, Lihi, Malleable hydrogel hybrids made of self-assembled peptides and biocompatible polymers and uses thereof.
    상세보기
  43. Wang, James H.; Shi, Bo; Lee, JaeHong; Topolkaraev, Vasily A.; Scholl, Neil T.; Kim, YoungSook, Melt processed antimicrobial composition.
    상세보기
  44. Topolkaraev, Vasily A.; Scholl, Neil T., Melt-blended protein composition.
    상세보기
  45. Topolkaraev, Vasily A.; Scholl, Neil T., Melt-blended protein composition.
    상세보기
  46. Tijssen, Peter; Szelei, Jozsef; Zadori, Zoltan, Method for detecting infectious parvovirus in pharmaceutical preparations.
    상세보기
  47. Latino, Massimo; Ghidorsi, Luigi; Ortenzi, Giovanni, Method for dissolution testing of solid compositions containing digestive enzymes.
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  48. Siegel, Steven; Winey, Karen, Method of maintaining therapeutic risperidone levels in a PLA:PLGA implant.
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  50. Kelleher-Andersson, Judith, Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration.
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  51. Kelleher-Andersson, Judith, Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration using isothiazolopyrimidinones.
    상세보기
  52. Kelleher-Andersson, Judith, Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration using isothiazolopyrimidinones.
    상세보기
  53. Kelleher-Andersson, Judith, Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration using isothiazolopyrimidinones.
    상세보기
  54. Kelleher-Anderson, Judith, Methods and compositons for stimulating neurogenesis and inhibiting neuronal degeneration.
    상세보기
  55. Brown, Larry; McGeehan, John K.; Rashba-Step, Julia; Scott, Terrence L., Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation.
    상세보기
  56. Persyn, Joseph T.; McDonough, Joseph A.; Vail, Neal K.; Barlow, Darren E.; Zwiener, Albert M.; Slovin, Eliot M., Methods for preparing biodegradable microparticle formulations containing pharmaceutically active agents.
    상세보기
  57. Ortenzi, Giovanni; Ghidorsi, Luigi, Methods for removing viral contaminants from pancreatic extracts.
    상세보기
  58. Darvari, Ramin; Lambert, Adam; Rashba-Step, Julia E.; Yang, Mark X.; Zhang, Junhong; O'Connell, Ed, Methods of processing compositions containing microparticles.
    상세보기
  59. Piran, Uri; Mehr, Eugene; Brown, Larry R.; McGeehan, John K.; O'Connell, Ed, Methods of processing compositions containing microparticles.
    상세보기
  60. Piran, Uri, Methods of processing multi-phasic dispersions.
    상세보기
  61. Canham, Leigh T.; Barrett, Christopher P.; Cox, Timothy I.; Wright, Peter J.; Bowditch, Andrew P., Methods of producing mesoporous drug delivery implants.
    상세보기
  62. Canham, Leigh T.; Barrett, Christopher P.; Cox, Timothy I.; Wright, Peter J.; Bowditch, Andrew P., Methods of producing porous resorbable implants.
    상세보기
  63. Hall, John William; Boyd, Randal; Neyme, Dylan; Ferguson, F. Mark, Methods, systems, and apparatuses for manufacturing rotational spun appliances.
    상세보기
  64. Brown, Larry R.; Giannoukakis, Nick; Gillis, Kimberly A.; Trucco, Massimo, Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes.
    상세보기
  65. Maio, Mario, Microspheres of pancreatic enzymes with high stability and production method thereof.
    상세보기
  66. Maio, Mario, Microspheres of pancreatic enzymes with high stability and production method thereof.
    상세보기
  67. Masters, David B.; Berg, Eric P., Mucoadhesive drug delivery devices and methods of making and using thereof.
    상세보기
  68. Scholl, Neil T.; Topolkaraev, Vasily A., Natural, multiple release and re-use compositions.
    상세보기
  69. Topolkaraev, Vasily A.; Scholl, Neil T.; Kim, YoungSook; Koenig, David W.; Lee, JaeHong, Natural, multiple use and re-use, user saturated wipes.
    상세보기
  70. Brown, Larry R.; Gillis, Kimberly A.; Gallo, Michael V., Nucleic acid microparticles for pulmonary delivery.
    상세보기
  71. Brown, Larry R.; Scott, Terrence L.; Lafreniere, Debra; Bisker-Leib, Vered, Nucleic acid microspheres, production and delivery thereof.
    상세보기
  72. Scott, Terrence; Lafreniere, Debra; Bisker-Leib, Vered; Brown, Larry, Nucleic acid microspheres, production and delivery thereof.
    상세보기
  73. Arvinte, Tudor; Schote, Uwe Thomas; Sigg, Juergen, Pharmaceutical compositions comprising TGF-beta.
    상세보기
  74. Hossainy, Syed F. A.; Glauser, Thierry, Phase-separated block copolymer coatings for implantable medical devices.
    상세보기
  75. Pacetti, Stephen Dirk; Tang, Yiwen; Hossainy, Syed Faiyaz Ahmed, Plasticizers for coating compositions.
    상세보기
  76. Siegel, Steven J.; Winey, Karen I.; Gur, Raquel E.; Lenox, Robert H., Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use.
    상세보기
  77. Siegel, Steven J.; Winey, Karen I.; Gur, Raquel E.; Lenox, Robert H., Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use.
    상세보기
  78. Seo, Min-Hyo; Choi, In-Ja, Polymeric composition for solubilizing poorly water soluble drugs and process for the preparation thereof.
    상세보기
  79. Sawhney Amarpreet S. ; Enscore David J. ; Goodrich Stephen D. ; Nason William C. ; Yao Fei ; Weaver Douglas ; Jarrett Peter K. ; Coury Arthur J. ; Rudowsky Ronald S. ; Powell Michelle D. ; Avila Luis, Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
    상세보기
  80. Sawhney Amarpreet S. ; Jarrett Peter K. ; Coury Arthur J. ; Rudowsky Ronald S. ; Powell Michelle D. ; Avila Luis Z. ; Enscore David J. ; Goodrich Stephen D. ; Nason William C. ; Yao Fei ; Weaver Doug, Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
    상세보기
  81. Sawhney,Amarpreet S.; Jarrett,Peter K.; Coury,Arthur J.; Rudowsky,Ronald S.; Lyman,Michelle D.; Avila,Luis Z.; Enscore,David J.; Goodrich,Stephen D.; Nason,William C.; Yao,Fei; Weaver,Douglas; Barman, Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
    상세보기
  82. Ashton, Paul; Guo, Hong; Chen, Jianbing; Canham, Leigh, Porous silicon drug-eluting particles.
    상세보기
  83. Ashton, Paul; Guo, Hong; Chen, Jianbing; Canham, Leigh T., Porous silicon drug-eluting particles.
    상세보기
  84. Ashton, Paul; Guo, Hong; Chen, Jianbing; Canham, Leigh T., Porous silicon drug-eluting particles.
    상세보기
  85. Eller, Zeke; Hall, John William; Kellar, Robert S.; Simmons, Rachel Lynn; Radford, Robert J.; Dolmatch, Bart, Process of making a stent.
    상세보기
  86. Shimizu, Hisayoshi; Nonomura, Muneo; Futo, Tomomichi; Mukai, Kei, Producing a sustained-release preparation.
    상세보기
  87. Anneaux, Bruce L.; Ballard, Robert L., Prosthetic device including electrostatically spun fibrous layer and method for making the same.
    상세보기
  88. Anneaux, Bruce L.; Ballard, Robert L., Prosthetic device including electrostatically spun fibrous layer and method for making the same.
    상세보기
  89. Masters, David B., Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof.
    상세보기
  90. Masters, David B.; Berg, Eric P., Protein biomaterials and biocoacervates and methods of making and using thereof.
    상세보기
  91. Masters, David B.; Berg, Eric P., Protein biomaterials and biocoacervates and methods of making and using thereof.
    상세보기
  92. Masters, David B., Protein matrix materials, devices and methods of making and using thereof.
    상세보기
  93. Masters, David B., Protein matrix materials, devices and methods of making and using thereof.
    상세보기
  94. Brown, Larry; Bisker-Leib, Vered; LaFreniere, Debra; McGeehan, John; Rashba-Step, Julia; Scott, Terrence, Protein microspheres having injectable properties at high concentrations.
    상세보기
  95. Brown, Larry R.; Yang, Mark X.; O'Connell, Ed, Protein microspheres retaining pharmacokinetic and pharmacodynamic properties.
    상세보기
  96. Topolkaraev, Vasily A.; Scholl, Neil T.; Lee, JaeHong; Ambrose, Dianna L.; Kim, YoungSook, Protein stabilized antimicrobial composition formed by melt processing.
    상세보기
  97. Topolkaraev, Vasily A.; Scholl, Neil T.; Lee, Jaehong; Ambrose, Dianna L.; Kim, YoungSook, Protein stabilized antimicrobial composition formed by melt processing.
    상세보기
  98. Siegel, Steven; Winey, Karen, Risperidone-containing PLA:PGA implants and methods of use thereof.
    상세보기
  99. Siegel, Steven; Winey, Karen, Risperidone-containing implants and methods of use thereof.
    상세보기
  100. Hall, John William; Eller, Zeke; Kellar, Robert S.; Simmons, Rachel Lynn; Dolmatch, Bart; Mower, Wayne; Radford, Robert J., Rotational spun material covered medical appliances and methods of manufacture.
    상세보기
  101. Hall, John William; Eller, Zeke; Kellar, Robert S.; Simmons, Rachel Lynn; Dolmatch, Bart; Mower, Wayne; Radford, Robert J., Rotational spun material covered medical appliances and methods of manufacture.
    상세보기
  102. Ortenzi, Giovanni; Marconi, Marco; Mapelli, Luigi, Stable digestive enzyme compositions.
    상세보기
  103. Davis, Stanley Stewart; Wells, Andrew, Surface modification of lamellar particles.
    상세보기
  104. Cheng, Wei; Fevre, Mareva B.; Hedrick, James L.; Ibrahim, Nor Lizawati; Lee, Ashlynn L. Z.; Ng, Victor W. L.; Ono, Robert J.; Yang, Chuan; Yang, Yi Yan, Vitamin functionalized gel-forming block copolymers for biomedical applications.
    상세보기
  105. Lee, JaeHong; Topolkaraev, Vasily A.; Koenig, David W.; Scholl, Neil T.; Kim, YoungSook; Wang, James H., Wipe coated with a botanical emulsion having antimicrobial properties.
    상세보기
  106. Masters, David B.; Berg, Eric P., Wound treatments with crosslinked protein amorphous biomaterials.
    상세보기
  107. Seo, Min-Hyo; Kim, Bong-Oh; Choi, In-Ja; Shim, Myung-Seob, pH responsive biodegradable polylactic acid derivatives forming polymeric micelles and uses thereof for poorly water soluble drug delivery.
    상세보기

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