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A cosmetic or pharmaceutical composition containing a synergistically active oxidation inhibiting system consisting of a combination of a ginkgo extract and at least one polyphenol compound. For example, the ginkgo extract may be a hexane extract of ginkgo leaves and the polyphenol compound may be a

A cosmetic or pharmaceutical composition containing a synergistically active oxidation inhibiting system consisting of a combination of a ginkgo extract and at least one polyphenol compound. For example, the ginkgo extract may be a hexane extract of ginkgo leaves and the polyphenol compound may be a flavonoid. Said composition may be used to prevent and treat cell damage on the skin, scalp or mucosae by free radicals induced especially by atmospheric pollutants and/or ultraviolet radiation, and/or for controlling the phenomenon of accelerated skin ageing.

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A cosmetic or pharmaceutical composition comprising an antioxidizing system consisting of the combination of a ginkgo extract and at least one polyphenol compound, said ginkgo extract being obtained by extraction of ginkgo leaves with a nonpolar solvent; wherein said polyphenol compound is selected

A cosmetic or pharmaceutical composition comprising an antioxidizing system consisting of the combination of a ginkgo extract and at least one polyphenol compound, said ginkgo extract being obtained by extraction of ginkgo leaves with a nonpolar solvent; wherein said polyphenol compound is selected from the group consisting of a flavonoid, carnosic acid, carnosol, a 2,5-dihydroxy benzoic acid, a compound of formula (III) [Figure] (III) wherein R1″represents －O－Alk, OH or －N(r′)(r″) wherein Alk represents linear or branched C1-C20 alkyl; linear or branched C1-C20 alkyl substituted by one or more hydroxyl groups; linear or branched C1-C20 alkyl substituted by one or more alkoxy groups, or Alk representing C2-C20 alkenyl; r′and r″, each independently represent H, C1-C20 alkyl, C2-C6 hydroxyalkyl or C3-C6 polyhydroxyalkyl; r represents a number, including zero, so that said －(CH2)r－COR1″contains at most 21 carbon atoms; and R2″and R3″, each independently, represent H or C1-C4 alkyl, or R2″represents C1-C4 alkoxy, a C1-C8 alkyl ester or caffeic acid, a phytol ester of caffeic acid, a caffeic acid amide of formula (V) [Figure] (V) wherein Z′represents C1-C8 alkyl, and tannic acid; said flavonoids being selected from the group consisting of taxifolin, catechin, epicatechin, eriodictyol, naringenin, rutin, troxerutin, chrysin, tangeretin, luteolin, epigallocatechin, epigallocatechin gallate, quercetin, fisetin, kaempferol, galangin, gallocatechin and epicatechin gallate. A cosmetic or pharmaceutical composition comprising an antioxidizing system consisting of the combination of a ginkgo extract and at least one polyphenol compound, said ginkgo extract being obtained by extraction of ginkgo leaves with a nonpolar solvent, wherein said polyphenol is selected from the group consisting of a flavonoid, carnosic acid, carnosol, a 2,5-dihydroxybenzoic acid, a compound of formula (III) [Figure] (III) wherein R1″represents －O－Alk, OH or －N(r′)(r″) wherein Alk represents linear or branched C1-C20 alkyl; linear or branched C1-C20 alkyl substituted by one or more hydroxy groups; linear or branched C1-C20 alkyl substituted by one or more alkoxy groups, or Alk representing C2-C20 alkenyl; r′and r″, each independently represents H, C1-C20 alkyl, C2-C6 hydroxyalkyl or C3-C6 polyhydroxyalkyl; r represents a number, including zero, so that said －(CH2)r－COR1″contains at most 21 carbon atoms; and R2″and R3″, each independently, represents H or C1-C4 alkyl, or R2″represents C1-C4 alkoxy, a C1-C8 alkyl ester or caffeic acid, a phytol ester or caffeic acid, a caffeic acid amide of formula (V) [Figure] (V) wherein Z′represents C1-C8 alkyl, and tannic acid, wherein said flavonoids are selected from the group consisting of compounds of formula (I) and formula (II) [Figure] (I) [Figure] (II) wherein A″, B″, C″and D″, independently of one another, represent H or OH; E″represents H, OH or OX′, where X′represents [Figure] F″, G″and J″represent, independently of one another, H or OH; and X1 represents －CH2－, －CO－or －CHOH－; A′, C′and D′, independently of one another, represent H, OH or OCH3; E′represents H, OH or OR′, where R′represents a residue of rutinose; and B′, F′, G′and J′, independently of one another, represent H, OH, OCH3 or －OCH2－CH2－OH.