초록

A polymer network useful as a lubricous coating, the polymer network comprising a reaction product of a vinyl prepolymer and an uncrosslinked hydrogel retained within the reaction product such that the network exhibits a greater lubricity when wet.

대표청구항 ▼

An angioplasty catheter including a composition coating the distal end of said catheter, the composition comprising: the reaction product of vinyl monomers selected from the group consisting of mono-, di- and tri-acrylates, styrene, and divinyl benzene said monomers being polymerizable to form a cro

An angioplasty catheter including a composition coating the distal end of said catheter, the composition comprising: the reaction product of vinyl monomers selected from the group consisting of mono-, di- and tri-acrylates, styrene, and divinyl benzene said monomers being polymerizable to form a crosslinked polymer that adheres to the surface of the device and resists degradation from rubbing and hydration; a polymerization initiator; and an uncrosslinked linear, water-soluble, hydrophilic hydrogel selected from the group consisting of polyethylene oxide, polyacrylic acid, polyacrylamide, poly (sodium-4-styrenesulfonate), poly(3-hydroxybutyric acid), polyvinylpyrrolidone and 2-hydroxyethyl methacryate, said hydrogel being intertwined with the polymer so as to prevent the hydrogel from leaching out of the coating composition, the hydrogel being lubricous when wet and substantially unnoticeable on the surface when dry, and said monomers being polymerized in the presence of the hydrogel; and a solvent.