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Fourier detection of species migrating in a microchannel 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • G01N-021/00
출원번호 US-0683080 (1996-07-16)
발명자 / 주소
  • Parce J. Wallace (Palo Alto CA)
출원인 / 주소
  • Caliper Technologies Corp. (Palo Alto CA 02)
인용정보 피인용 횟수 : 253  인용 특허 : 16

초록

The present invention provides a microfluidic system for fast, accurate and low cost electrophoretic analysis of materials in the fields of chemistry, biochemistry, biotechnology, molecular biology and numerous other fields. Light from periodically spaced regions along a channel in the microfluidic

대표청구항

A microfluidic system for high-speed electrophoretic analysis of subject materials, said system comprising a channel in a substrate, said channel holding said subject materials in solution in an electric field so that said materials move through said channel and separate into species bands according

이 특허에 인용된 특허 (16)

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  188. Chow, Calvin Y. H., Multi-layer microfluidic devices.
  189. Bienvenue, Joan M; Landers, James P; Scott, Orion N, Multiple-sample microfluidic chip for DNA analysis.
  190. Parce, J. Wallace; Chow, Andrea W., Non-mechanical valves for fluidic systems.
  191. Parce, J. Wallace; Chow, Andrea W., Non-mechanical valves for fluidic systems.
  192. Manz, Andreas; Bousse, Luc J., Open-Field serial to parallel converter.
  193. Manz,Andreas; Bousse,Luc J., Open-field serial to parallel converter.
  194. Bell, H. Randall; Pettit, John W; Landers, James P; Bienvenue, Joan M; Marchiarullo, Daniel J; Root, Brian E; Scott, Orion N, Optical approach for microfluidic DNA electrophoresis detection.
  195. Naessens, Kris; Bockstaele, Ronny; Luyssaert, Bert; Baets, Roeland, Optical characterisation methods and systems.
  196. Kopf-Sill Anne R. ; Chow Andrea W., Optimized high-throughput analytical system.
  197. Kopf-Sill, Anne R.; Chow, Andrea W., Optimized high-throughput analytical system.
  198. Burd Mehta, Tammy, PCR compatible nucleic acid sieving matrix.
  199. Olivares, Jos? A.; Stark, Peter C., Particle sizer and DNA sequencer.
  200. Welle, Richard P., Phase-change valve apparatuses.
  201. Welle, Richard P., Phase-change valve apparatuses.
  202. Brahmasandra, Sundaresh N.; Craig, Elizabeth, Polynucleotide capture materials, and methods of using same.
  203. Brahmasandra, Sundaresh N.; Craig, Elizabeth, Polynucleotide capture materials, and methods of using same.
  204. Brahmasandra, Sundaresh N.; Craig, Elizabeth, Polynucleotide capture materials, and methods of using same.
  205. Brahmasandra, Sundaresh N.; Craig, Elizabeth, Polynucleotide capture materials, and methods of using same.
  206. J. Wallace Parce ; Anne R. Kopf-Sill ; Luc J. Bousse, Pre-disposed assay components in microfluidic devices and methods.
  207. Chow,Andrea W., Prevention of precipitate blockage in microfluidic channels.
  208. J. Wallace Parce ; Andrea W. Chow, Prevention of surface adsorption in microchannels by application of electric current during pressure-induced flow.
  209. Parce,J. Wallace; Chow,Andrea W., Prevention of surface adsorption in microchannels by application of electric current during pressure-induced flow.
  210. Kennedy, Michael J.; Gefter, Alexander A., Priming module for microfluidic chips.
  211. Shuck,Gary L., Process for filling microfluidic channels.
  212. Handique, Kalyan; Parunak, Gene; Kehrer, Aaron; Wu, Betty; Ganesan, Karthik, Processing particle-containing samples.
  213. Handique, Kalyan; Parunak, Gene; Kehrer, Aaron; Wu, Betty; Ganesan, Karthik, Processing particle-containing samples.
  214. Handique, Kalyan; Parunak, Gene; Kehrer, Aaron; Wu, Betty; Ganesan, Karthik, Processing particle-containing samples.
  215. Wu, Betty; Althaus, John S.; Brahmasandra, Sundaresh N.; Handique, Kalyan; Phadke, Nikhil, Processing polynucleotide-containing samples.
  216. Duffy, Patrick; Wilson, Kerry; Handique, Kalyan; Williams, Jeff, Rack for sample tubes and reagent holders.
  217. Duffy, Patrick; Wilson, Kerry; Handique, Kalyan; Williams, Jeff, Rack for sample tubes and reagent holders.
  218. Parce, J. Wallace, Rapid detection of species bands in a separation conduit.
  219. Patil, Vishal; Mollova, Emilia; Gilmanshin, Rudolf, Reaction chamber.
  220. Wilson, Kerry; Handique, Kalyan; Williams, Jeff; Brahmasandra, Sundaresh N., Reagent holder.
  221. Wilson, Kerry; Handique, Kalyan; Brahmasandra, Sundaresh N.; Williams, Jeff, Reagent holder, and kits containing same.
  222. Handique, Kalyan; Springer, Theodore, Reagent tube.
  223. Gubatayao, Thomas Catalino; Handique, Kalyan; Ganesan, Karthik; Drummond, Daniel M., Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection.
  224. Parce, J. Wallace; Nikiforov, Theo T.; Mehta, Tammy Burd; Kopf Sill, Anne R.; Chow, Andrea W.; Knapp, Michael R., Sequencing by incorporation.
  225. Parce, J. Wallace; Nikiforov, Theo T.; Mehta, Tammy Burd; Kopf-Sill, Anne R.; Chow, Andrea W.; Knapp, Michael R., Sequencing by incorporation.
  226. Parce,J. Wallace; Nikiforov,Theo T.; Mehta,Tammy Burd; Kopf Sill,Anne R.; Chow,Andrea W.; Knapp,Michael R., Sequencing by incorporation.
  227. Parce,J. Wallace; Nikiforov,Theo T.; Mehta,Tammy Burd; Kopf Sill,Anne R.; Chow,Andrea W.; Knapp,Michael R., Sequencing by incorporation.
  228. Lentz, Ammon David; St-Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Single piece reagent holder.
  229. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Single piece reagent holder.
  230. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Single piece reagent holder.
  231. Kuhr Werner G. ; Singhal Pankaj ; Brazill Sara Ann, Spatially-encoded analyte detection.
  232. Miles, Robin R.; Wang, Amy Wei-Yun; Mariella, Jr., Raymond P., Stepped electrophoresis for movement and concentration of DNA.
  233. Yang Hua ; Sundberg Steven A., Surface coating for microfluidic devices that incorporate a biopolymer resistant moiety.
  234. Yang, Hua; Sundberg, Steven A., Surface coating for microfluidic devices that incorporate a biopolymer resistant moiety.
  235. Yang, Hua; Sundberg, Steven A., Surface coating for microfluidic devices that incorporate a biopolymer resistant moiety.
  236. Yang, Hua; Sundberg, Steven A., Surface coating for microfluidic devices that incorporate a biopolymer resistant moiety.
  237. Ganesan, Karthik; Handique, Kalyan, Systems and methods for thermal actuation of microfluidic devices.
  238. Ganesan, Karthik; Handique, Kalyan, Systems and methods for thermal actuation of microfluidic devices.
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  240. Ganesan, Karthik; Handique, Kalyan, Systems and methods for thermal actuation of microfluidic devices.
  241. Burns, Mark A.; Johnson, Brian N.; Chen, Michael, Thermal microvalves.
  242. Chow, Calvin Y. H., Total analyte quantitation.
  243. Chow,Calvin Y. H., Total analyte quantitation.
  244. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Unitized reagent strip.
  245. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Unitized reagent strip.
  246. Lentz, Ammon David; St. Pierre, Richard; Livingston, Dwight; Steel, Adam Bruce, Unitized reagent strip.
  247. Farinas, Javier Anibal; Wada, H. Garrett, Use of Nernstein voltage sensitive dyes in measuring transmembrane voltage.
  248. Farinas, Javier Anibal; Wada, H. Garrett, Use of nernstein voltage sensitive dyes in measuring transmembrane voltage.
  249. Farinas, Javier Anibal; Wada, H. Garrett, Use of nernstein voltage sensitive dyes in measuring transmembrane voltage.
  250. Chien,Ring Ling, Voltage/current testing equipment for microfluidic devices.
  251. Murphy, Matthew B.; Dubrow, Robert S., Western blot by incorporating an affinity purification zone.
  252. Murphy, Matthew B.; Dubrow, Robert S., Western blot by incorporating an affinity purification zone.
  253. Murphy, Matthew B; Dubrow, Robert S., Western blot by incorporating an affinity purification zone.
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