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| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0701405 (1996-08-22) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 737 인용 특허 : 0 |
The drug loaded stent includes an expandable stent structural member, and a planar sheet of polymeric material attached to the outside of the expandable stent structural member. The polymeric material is preferably bioabsorbable, and loaded or coated with a therapeutic agent or drug to reduce or pre
The drug loaded stent includes an expandable stent structural member, and a planar sheet of polymeric material attached to the outside of the expandable stent structural member. The polymeric material is preferably bioabsorbable, and loaded or coated with a therapeutic agent or drug to reduce or prevent restenosis in the vessel being treated. The polymer material can be attached to the metal stent at one or more points, and wrapped in a coil around the stent in an unexpanded state, to uncoil and expand in diameter to substantially match the expanded diameter of the metal stent; or can be wrapped tightly around the stent structural member and attached to itself, to stretch radially when the stent structural member is expanded. In another currently preferred embodiment, a combination of a stent structural member and a polymeric film wrapping can be provided with a coating of lubricious material. The lubricious material can be polyethylene oxide, polyethylene glycol, polyethylene acetate, polyvinyl pyrrolidone, polyvinyl alcohol, polyacrylamide, hydrophilic soft segment urethanes, some natural gums, polyanhydrides or other similar hydrophilic polymers, and combinations thereof. The layer of lubricious material protects the stent from the guide or the body lumen in which the stent is inserted by providing a low friction surface over the stents.
A drug loaded stent, comprising: an expandable stent structural member; a sheet of polymeric material disposed on the stent structural member, said sheet of polymeric material being wrapped about the stent structural member at least one time to form a coil having an interior portion, an exterior por
A drug loaded stent, comprising: an expandable stent structural member; a sheet of polymeric material disposed on the stent structural member, said sheet of polymeric material being wrapped about the stent structural member at least one time to form a coil having an interior portion, an exterior portion, and an exterior end portion, said sheet of polymeric material being loaded with a therapeutic agent; and at least one strip of elastic material, one end of said at least one strip of elastic material being attached to the exterior portion of the coil, and an opposing end of the strip of elastic material being attached to another portion of the exterior of the coil, said strip of elastic material extending across the exterior end portion of the coil, to secure the coil on the stent, and such that said sheet of polymeric material is free to uncoil when said stent structural member is expanded, to substantially match the expansion of said stent structural member.
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