초록 ▼

The present invention provides an apparatus and method for repairing a diseased vessel at the site of an aneurysm, graft or stenosis. A polymeric self-hardening or self-curing material is introduced into the diseased area. The material is delivered via catheter and allowed to polymerize or cure in s

The present invention provides an apparatus and method for repairing a diseased vessel at the site of an aneurysm, graft or stenosis. A polymeric self-hardening or self-curing material is introduced into the diseased area. The material is delivered via catheter and allowed to polymerize or cure in situ forming a foam plug in the vessel. A lumen is then created through the foam plug by such means as an atherectomy catheter, to recanalize the vessel. The polymeric material may also be hardened in situ by change in pH or ionic concentration, organic solvents, by permeation of a secondary material capable of precipitation, or by exposure to heat, light or laser energy. In blood, the device may be hardened through a cooperative effect of coagulation, precipitation or ionization. The device can be made of biodegradable material impregnated with growth factors, mitogenic factors or other determinants. The catheter itself may be an ultrasonic imaging catheter.

대표청구항 ▼

[ What is claimed is:] [1.] A medical device comprising a biocompatible polymeric material which is adapted to be delivered in a first state to a repair site in a vessel, said material being adapted to fill the repair site in its first state and being further adapted to be hardened in situ to form a

[ What is claimed is:] [1.] A medical device comprising a biocompatible polymeric material which is adapted to be delivered in a first state to a repair site in a vessel, said material being adapted to fill the repair site in its first state and being further adapted to be hardened in situ to form a plug at the repair site, said plug being adapted to have to lumen formed therein in situ, whereby said vessel is recanalized and a polymeric graft is created therein.