초록

The present invention also relates to the use of iontophoresis to determine the level of a charged molecule in a living mammal, and with the use of a feedback mechanism, administer appropriate levels of therapeutic substances.

대표청구항 ▼

[ We claim:] [1.] An iontophoretic method for the substantially continuously in vivo monitoring of blood glucose in a mammal, the method comprising the steps of:(a) placing a device comprised of a first electrically conducting means, a second electrically conducting means, and at least one collectio

[ We claim:] [1.] An iontophoretic method for the substantially continuously in vivo monitoring of blood glucose in a mammal, the method comprising the steps of:(a) placing a device comprised of a first electrically conducting means, a second electrically conducting means, and at least one collection reservoir on the skin or mucous membrane of the mammal to be monitored, wherein said second electrically conducting means is physically and electrically separated from said first electrically conducting means,(b) connecting said device to an electrical source to create an electrical circuit,(c) continuously applying a constant current in said electrical circuit to cause said blood glucose to migrate into said collection reservoir, and(d) collecting and monitoring the glucose in said collection reservoir, with the proviso that the contact of the device on the skin or mucous membrane and the collection occurs at physiologically acceptable pH conditions.