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Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-C]quinolin-4-amine 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/44
  • A61K-009/70
출원번호 US-0471440 (1995-05-31)
발명자 / 주소
  • Wick Steven M.
  • Schultz Helen Jensen
  • Nelson Gregory R.
  • Mitra Amit K.
  • Berge Stephen M.
출원인 / 주소
  • Riker Laboratories, Inc.
대리인 / 주소
    Griswold
인용정보 피인용 횟수 : 39  인용 특허 : 8

초록 ▼

Pharmaceutical formulations and adhesive-coated sheet materials for the topical and/or transdermal delivery of 1-isobutyl-1H-imidazo[4,5-c]-quinolin-4-amine, including creams, ointments and pressure-sensitive adhesive compositions. Pharmacological methods of using the formulations and the adhesive-c

대표청구항 ▼

[ What is claimed is:] [1.] A substantially non-irritating pharmaceutical formulation for topical and/or transdermal administration of 1 -isobutyl- 1H-imidazo[4,5 -c]quinolin-4-amine, which formulation comprises:(a) a therapeutically effective amount of 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine;(

이 특허에 인용된 특허 (8)

  1. Gerster John F. (Woodbury MN), 1H-Imidazo[4,5-c]quinolin-4-amines and antiviral use.
    상세보기
  2. Mahjour Majid (Morris Plains NJ) Iyer Uma (Mendham NJ) Fawzi Mahdi B. (Flanders NJ), Penetration enhancement system.
    상세보기
  3. Patel Dinesh C. (Murray UT) Chang Yunik (Lakewood NJ), Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols.
    상세보기
  4. Eckert Theodor (Muenster DEX) Kemper Fritz H. (Muenster DEX) Wischniewski Martin (Neustadt a. Rbge. DEX) Hempel Reinhard (Hanover DEX), Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparati.
    상세보기
  5. Cheng Yu-Ling (Cupertino CA) Nedberge Diane E. (Los Altos CA) Sugihara Edna (Mountain View CA), Skin permeation enhancer compositions using glycerol monolaurate.
    상세보기
  6. Kigasawa Kazuo (Tokyo JPX) Ohtani Hideaki (Tokyo JPX) Tanaka Makoto (Tokyo JPX) Hayashida Shigeru (Tokyo JPX), Soft patch.
    상세보기
  7. Johnson Dee L. (Woodbury MN) Senta Therese A. (Minneapolis MN) Sirvio Larry M. (Cottage Grove MN), Topical medicament preparations.
    상세보기
  8. Wick Steven M. (Oakdale MN), Transdermal nitroglycerin delivery system.
    상세보기

이 특허를 인용한 특허 (39)

  1. Lindstrom, Kyle J.; Merrill, Bryon A.; Haraldson, Chad A.; Rice, Michael J.; Kshirsagar, Tushar A.; Heppner, Philip D.; Wurst, Joshua R.; Niwas, Shri; Johannessen, Sarah C., Alkoxy substituted imidazoquinolines.
    상세보기
  2. Krepski, Larry R.; Dellaria, Jr., Joseph F.; Duffy, Daniel E.; Amos, David T.; Zimmermann, Bernhard M.; Moser, William H., Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines.
    상세보기
  3. Ma, David Q.; Perman, Christopher S.; Skwierczynski, Raymond D.; Hedenstrom, John C., Aqueous gel formulations containing immune response modifiers.
    상세보기
  4. Perman, Christopher S.; Skwierczynski, Raymond D.; Ma, David Q.; Hedenstrom, John C., Aqueous gel formulations containing immune response modifiers.
    상세보기
  5. Niwas, Shri; Merrill, Bryon A.; Heppner, Philip D.; Kshirsagar, Tushar A.; Lundquist, Jr., Gregory D.; Amos, David T.; Lindstrom, Kyle J., Aryl substituted imidazonaphthyridines.
    상세보기
  6. Bonk, Jason D.; Dellaria, Jr., Joseph F., Arylalkenyl and arylalkynyl substituted imidazoquinolines.
    상세보기
  7. Lindstrom, Kyle J.; Martin, Hugues M. H.; Merrill, Bryon A.; Rice, Michael J.; Wurst, Joshua R.; Haraldson, Chad A.; Kshirsagar, Tushar A.; Heppner, Philip D.; Niwas, Shri; Griesgraber, George W.; Radmer, Matthew R., Aryloxy and arylalkyleneoxy substituted imidazoquinolines.
    상세보기
  8. Prince, Ryan B.; Rice, Michael J.; Wurst, Joshua R.; Merrill, Bryon A.; Kshirsagar, Tushar A.; Heppner, Philip D., Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines.
    상세보기
  9. Carson, Dennis A.; Cottam, Howard B.; Wrasidlo, Wolfgang; Wu, Christina C. N.; Daniels, Gregory A., Conjugates of synthetic TLR agonists and uses therefor.
    상세보기
  10. Carson, Dennis A.; Cottam, Howard B.; Wrasidlo, Wolfgang; Wu, Christina C. N.; Daniels, Gregory A., Conjugates of synthetic TLR agonists and uses therefor.
    상세보기
  11. Carson, Dennis A.; Wrasidlo, Wolfgang; Wu, Christina C. N., Conjugates of synthetic TLR agonists and uses therefor.
    상세보기
  12. Velez-Bernal, Ivan Dario; Robledo-Restrepo, Sara Maria; Robledo-Restrepo, Martha Beatriz; Ceballos-Maya, Alba Lucia; Giraldo-Alzate, Newar Andres; Gomez-Zuluaga, Alvaro; Zuluaga-Rivera, Juan Jose, Cream formulation with amphotericin B and oil in water useful for topical application to mucous tissue and skin against diseases produced by leishmaniasis.
    상세보기
  13. Abram, Albert Zorko; Goldstein, Iulian, Fatty acid pharmaceutical foam.
    상세보기
  14. Abram, Albert Zorko; Goldstein, Iulian, Fatty acid pharmaceutical foam.
    상세보기
  15. Yu, Chongxi, High penetration prodrug compositions of 1H-imidazo[4,5-C]quinolin-4-amines and 1H-imidazo[4,5-C]quinolin-4-amine-related compounds.
    상세보기
  16. Yu, Chongxi, High penetration prodrug compositions of 1H-imidazo[4,5-c]quinolin-4-amines and 1H-imidazo[4,5-c]quinolin-4-amine-related compounds and uses thereof.
    상세보기
  17. Kshirsagar, Tushar A.; Lundquist, Jr., Gregory D.; Amos, David T.; Dellaria, Jr., Joseph F.; Zimmermann, Bernhard M.; Heppner, Philip D., Hydroxylamine substituted imidazoquinolines.
    상세보기
  18. Bonk, Jason D.; Dellaria, Jr., Joseph F., Imidazoquinolinyl sulfonamides.
    상세보기
  19. Statham, Alexis S.; Nelson, Robert J., Immune response modifier formulations containing oleic acid and methods.
    상세보기
  20. Statham, Alexis S.; Nelson, Robert J., Immune response modifier formulations containing oleic acid and methods.
    상세보기
  21. Nordsiek, Michael T.; Gregory, Jefferson J., Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts.
    상세보기
  22. Nordsiek, Michael T.; Gregory, Jefferson J., Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts.
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  23. Nordsiek, Michael T.; Gregory, Jefferson J., Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts.
    상세보기
  24. Nordsiek, Michael T.; Gregory, Jefferson J., Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts.
    상세보기
  25. Miller, Richard L.; Lee, James H.; Owens, Mary L., Methods of improving skin quality.
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  26. Gregory, Jefferson J.; Nordsiek, Michael T., Methods of treating dermatological disorders and inducing interferon biosynthesis with shorter durations of imiquimod therapy.
    상세보기
  27. Gregory, Jefferson J.; Nordsiek, Michael T., Methods of treating dermatological disorders and inducing interferon biosynthesis with shorter durations of imiquimod therapy.
    상세보기
  28. Merrill, Bryon A.; Haraldson, Chad A.; Kshirsagar, Tushar A.; Niwas, Shri, Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines.
    상세보기
  29. Kshirsagar, Tushar A.; Lundquist, Jr., Gregory D.; Dellaria, Joseph F.; Radmer, Matthew R.; Zimmermann, Bernhard M., Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods.
    상세보기
  30. Kshirsagar, Tushar A.; Amos, David T.; Dellaria, Jr., Joseph F.; Heppner, Philip D.; Langer, Scott E.; Zimmermann, Bernhard M., Oxime substituted imidazo-containing compounds.
    상세보기
  31. Kshirsagar, Tushar A.; Lundquist, Gregory D.; Amos, David T.; Dellaria, Jr., Joseph F.; Zimmermann, Bernhard M.; Heppner, Philip D., Oxime substituted imidazoquinolines.
    상세보기
  32. Leoni, Lorenzo; Maj, Roberto; Pattarino, Franco; Vecchio, Carlo, Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration.
    상세보기
  33. Leoni, Lorenzo; Maj, Roberto; Pattarino, Franco; Vecchio, Carlo, Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration.
    상세보기
  34. Carson, Dennis A.; Cottam, Howard B.; Jin, Guangyi; Wu, Christina C. N.; Takabayashi, Kenji, Purine analogs.
    상세보기
  35. Hays, David S.; Danielson, Michael E.; Gerster, John F.; Niwas, Shri; Prince, Ryan B.; Kshirsagar, Tushar A.; Heppner, Philip D.; Moser, William H.; Moseman, Joan T.; Radmer, Matthew R.; Kavanagh, Maureen A.; Strong, Sarah A.; Bonk, Jason D., Pyrazolopyridines and analogs thereof.
    상세보기
  36. Griesgraber, George W.; Kshirsagar, Tushar A.; Slania, Sarah J.; Danielson, Michael E., Substituted chiral fused [1,2]imidazo[4,5-.
    상세보기
  37. Krepski, Larry R.; Dellaria, Jr., Joseph F.; Duffy, Daniel E.; Radmer, Matthew R.; Amos, David T., Substituted imidazo ring systems and methods.
    상세보기
  38. Carson, Dennis A.; Takabayashi, Kenji; Cottam, Howard B.; Chan, Michael; Wu, Christina C. N., TLR agonists.
    상세보기
  39. Carson, Dennis A.; Cottam, Howard B.; Hayashi, Tomoko; Chan, Michael, Toll-like receptor modulators and treatment of diseases.
    상세보기

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