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특허 상세정보

Method and implantable article for promoting endothelialization

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61L-027/00   
미국특허분류(USC) 523/113 ; 523/114 ; 424/423 ; 623/01 ; 623/011 ; 427/022.4 ; 514/08 ; 514/021
출원번호 US-0729537 (1996-10-11)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Fredrikson & Byron, P.A.
인용정보 피인용 횟수 : 208  인용 특허 : 7
초록

A porous material with an appropriate surface chemistry that promotes capillary endothelialization is disclosed. The material has a porosity that is sufficient to allow capillary endothelialization and a tenaciously bound adhesion molecule that promotes the ingrowth of endothelial cells into the porosity of the material.

대표
청구항

[ What is claimed is:] [1.] An article comprising an implantable medical device comprising a rigid, porous biomaterial selected from the group consisting of non-soluble synthetic polymers, metals and ceramics and providing a surface bearing immobilized adhesion molecules selected from the group consisting of fibronectin, laminin, collagen, and active peptide domains thereof, the adhesion molecules having been bound to each other or the surface of the biomaterial by the activation of one or more photoreactive groups covalently bound to the adhesion molecu...

이 특허를 인용한 특허 피인용횟수: 208

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