초록

or a pharmaceutically acceptable acid-addition salt thereof. Discomforting side effects can be minimized by optionally administering naltrexone, naloxone, or a mixture thereof during the early phases of treatment.

대표청구항 ▼

[ What is claimed:] [1.] A method for treating addiction to cocaine, amphetamine, or both in a patient, said method comprising:administering to the patient an effective amount of a compound having the formula: [ STR 6 ] wherein R.sup.1 is selected from the group consisting of hydrogen and C1 to C6 a

[ What is claimed:] [1.] A method for treating addiction to cocaine, amphetamine, or both in a patient, said method comprising:administering to the patient an effective amount of a compound having the formula: [ STR 6 ] wherein R.sup.1 is selected from the group consisting of hydrogen and C1 to C6 alkyl;R.sup.2 is selected from the group consisting of hydrogen, methyl, and ethyl;R.sup.3 is selected from the group consisting of hydrogen, methyl, C1 to C6 alkanoyl, C3 to C6 cycloalkanoyl, and pyridinecarbonyl;Q is a bivalent alkylene moiety; andY is selected from the group consisting of a halo-(C2 to C6)-alkenyl moiety having 1 or 2 chlorine or bromine atoms attached to the ethylenic carbon, a cycloalkyl moiety, a cyano moiety, and a cyano-(C3 to C6)-alkenyl moiety a pharmaceutically acceptable salt thereof.