초록 ▼

Medical devices for implantation into the body are coated with anti-infective and or anti-inflammatory agents. The medical devices can be, for example, endotracheal/tracheostomy tubes and catheters. The devices have a polymer coating containing an anti-infective agent and/or an anti-inflammatory age

Medical devices for implantation into the body are coated with anti-infective and or anti-inflammatory agents. The medical devices can be, for example, endotracheal/tracheostomy tubes and catheters. The devices have a polymer coating containing an anti-infective agent and/or an anti-inflammatory agent. The preferred anti-infective agent is iodine and the preferred anti-inflammatory agent is steroidal.

대표청구항 ▼

[ We claim:] [1.] An endoctracheal or tracheostomy tube for implantation into the body and coming into contact with body tissue and fluids comprising said endotracheal or tracheostomy tube having thereon a biocompatible, nonbioerodible polymer dissolved in a solvent to form a solution, the solution

[ We claim:] [1.] An endoctracheal or tracheostomy tube for implantation into the body and coming into contact with body tissue and fluids comprising said endotracheal or tracheostomy tube having thereon a biocompatible, nonbioerodible polymer dissolved in a solvent to form a solution, the solution being disposed on the exterior surface of the device and the solvent removed to form a uniform coating on the endotracheal or tracheostomy tube thereby coating said exterior surface and wherein said polymer coating is formed of non-hydrogel polymer being insoluble in a biological medium and soluble in an organic solvent, with said polymer coating containing effective amounts of iodine and an antiinflammatory agent sorbed therein, such that the iodine is released over a period of at least twenty-four hours by diffusion while the endotracheal or tracheostomy tube is implanted into the body.