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Method of treating or preventing type 1 diabetes by oral administration of insulin 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/28
출원번호 US-0456953 (1995-06-01)
발명자 / 주소
  • Weiner Howard L.
  • Eisenberth George
  • Hafler David Allen
  • Zhang Zhengi
출원인 / 주소
  • AutoImmune Inc.
대리인 / 주소
    Darby & Darby
인용정보 피인용 횟수 : 96  인용 특허 : 4

초록 ▼

Disclosed herein are methods for treating or preventing a disease in mammals having the characteristics of Type 1 diabetes comprising administering insulin or disease suppressive fragments of insulin or analogs thereof in oral or aerosol dosage forms to said mammals. Also disclosed herein are pharma

대표청구항 ▼

[ What is claimed is:] [1.] A method for suppressing autoimmune response against pancreatic beta cells in a mammal in need of suppression of said autoimmune response comprising orally or enterally administering to said mammal an effective amount of a composition comprising a fragment of insulin havi

이 특허에 인용된 특허 (4)

  1. Ecanow Bernard (Wilmette IL), Oral insulin and a method of making the same.
    상세보기
  2. Grau Ulrich (Hofheim am Taunus DEX), Pharmaceutical agent for the treatment of diabetes mellitus.
    상세보기
  3. Kidron Miriam (Jerusalem ILX) Ziv Ehud (Motza Ilit ILX) Bar-On Hanoch (Jerusalem ILX) Eldor Amiram (Jerusalem ILX), Pharmaceutical compositions containing insulin.
    상세보기
  4. Cavazza Claudio (35 ; Via Marocco Rome ITX 00144), Therapeutic method and compositions for the treatment of juvenile diabetes mellitus.
    상세보기

이 특허를 인용한 특허 (96)

  1. Wachtel, Herbert, Adapter, inhalation device, and atomizer.
    상세보기
  2. Adamo, Benoit; Polidoro, John M.; Overfield, Dennis; Sahi, Carl R.; Laurenzi, Brendan; Smutney, Chad C.; Kinsey, P. Spencer, Apparatus and method for simulating inhalation efforts.
    상세보기
  3. Adamo, Benoit; McLean, Scott; Smutney, Chad C.; Polidoro, John M.; Sahi, Carl R., Apparatus, system and method for measuring resistance of an inhaler.
    상세보기
  4. Ekwuribe, Nnochiri N.; Radhakrishnan, Balasingam, Calcitonin drug-oligomer conjugates, and uses thereof.
    상세보기
  5. Ekwuribe, Nnochiri N.; Radhakrishnan, Balasingam, Calcitonin drug-oligomer conjugates, and uses thereof.
    상세보기
  6. Stevenson, John J.; Moye-Sherman, Destardi, Catalysis of diketopiperazine synthesis.
    상세보기
  7. Stevenson, John J.; Moye-Sherman, Destardi, Catalysis of diketopiperazine synthesis.
    상세보기
  8. Radhakrishnan, Balasingam; Aggarwal, Diti; Ferro, Michelle; James, Kenneth D.; Malkar, Navdeep B.; Miller, Mark A.; Puskas, Monica; Ekwuribe, Nnochiri N., Cation complexes of insulin compound conjugates, formulation and uses thereof.
    상세보기
  9. Radhakrishnan, Balasingam; Aggarwal, Diti; Ferro, Michelle; James, Kenneth D.; Malkar, Navdeep B.; Miller, Mark A.; Puskas, Monica; Ekwuribe, Nnochiri N., Cation complexes of insulin compound conjugates, formulations and uses thereof.
    상세보기
  10. Harada, Tsuyoshi; Kanehiro, Hideo; Mizuguchi, Kiyoshi, Compositions and methods for treating non-alcoholic steatohepatitis.
    상세보기
  11. Mizuguchi, Kiyoshi; Harada, Tsuyoshi; Osada, Atsushi; Kawano, Hiroyuki; Ichioka, Masayuki, Compositions and methods for treating non-alcoholic steatohepatitis.
    상세보기
  12. Mizuguchi, Kiyoshi; Harada, Tsuyoshi; Osada, Atsushi; Kawano, Hiroyuki; Ichioka, Masayuki, Compositions and methods for treating non-alcoholic steatohepatitis.
    상세보기
  13. Eicher, Joachim; Graessl, Herbert; Janetzko, Mike; Jung, Andree; Meisenheimer, Martin; Wachtel, Herbert; Winkler, Robert Gerhard; Wuttke, Gilbert; Yu, Ying, Container, nebulizer and use.
    상세보기
  14. Grant, Marshall L.; Stowell, Grayson W.; Menkin, Paul, Diketopiperazine microparticles with defined specific surface areas.
    상세보기
  15. Leone-Bay, Andrea; Moye-Sherman, Destardi; Wilson, Bryan R., Diketopiperazine salts for drug delivery and related methods.
    상세보기
  16. Leone-Bay, Andrea; Moye-Sherman, Destardi; Wilson, Bryan R., Diketopiperazine salts for drug delivery and related methods.
    상세보기
  17. Besseler, Jens; Holakovsky, Holger; Argauer, Herbert; Gatz, Josef; Gorshoefer, Andreas, Dispenser with encoding means.
    상세보기
  18. Dunne, Stephen T.; Moser, Achim, Dispensing device, storage device and method for dispensing a formulation.
    상세보기
  19. Flores-Riveros, Jaime; Frincke, James M.; Reading, Christopher; Stickney, Dwight; Ahlem, Clarence N., Drug screening and treatment methods.
    상세보기
  20. Smutney, Chad C.; Adamo, Benoit; Laurenzi, Brendan F.; Kinsey, P. Spencer, Dry powder drug delivery system and methods.
    상세보기
  21. Smutney, Chad C.; Adamo, Benoit; Polidoro, John M.; Kinsey, P. Spencer; Overfield, Dennis; Sahi, Carl; Billings, Christine; Marino, Mark T., Dry powder drug delivery system and methods.
    상세보기
  22. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Bryant, Anthony, Dry powder inhaler and system for drug delivery.
    상세보기
  23. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Bryant, Anthony; He, Tom; Mann, Alfred, Dry powder inhaler and system for drug delivery.
    상세보기
  24. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Kraft, Kelly S.; Somerville, Karla, Dry powder inhaler and system for drug delivery.
    상세보기
  25. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfield, Dennis; Kraft, Kelly S.; Somerville, Karla, Dry powder inhaler and system for drug delivery.
    상세보기
  26. Smutney, Chad C.; Kinsey, P. Spencer; Sahi, Carl R.; Adamo, Benoit; Polidoro, John M.; McLean, Scott; Overfiled, Dennis; Bryant, Anthony, Dry powder inhaler and system for drug delivery.
    상세보기
  27. Radhakrishnan, Balasingam; Aggarwal, Diti; Ferro, Michelle; James, Kenneth D.; Malkar, Navdeep B.; Miller, Mark A.; Pavliv, Leo; Polowy, Karen; Puskas, Monica; Ekwuribe, Nnochiri N., Fatty acid formulations and oral delivery of proteins and peptides, and uses thereof.
    상세보기
  28. Radhakrishnan, Balasingam; Aggarwal, Diti; Ferro, Michelle; James, Kenneth D.; Malkar, Navdeep B.; Miller, Mark A.; Pavliv, Leo; Polowy, Karen; Puskas, Monica; Ekwuribe, Nnochiri N., Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof.
    상세보기
  29. Fabio, Karine; Guarneri, Joseph J.; Curley, Kieran; Grant, Marshall L.; Leone-Bay, Andrea, Heat-stable dry powder pharmaceutical compositions and methods.
    상세보기
  30. Grant, Marshall; Menkin, Paul; Stowell, Grayson W., High capacity diketopiperazine microparticles and methods.
    상세보기
  31. Grant, Marshall; Menkin, Paul; Stowell, Grayson W., High capacity diketopiperazine microparticles and methods.
    상세보기
  32. Hokenson, Mark; Oberg, Keith A., Increasing drug affinity for crystalline microparticle surfaces.
    상세보기
  33. Smutney, Chad C.; Leone-Bay, Andrea; Galarza, Jose M.; Munoz, Hector; Martin, George R.; Grant, Marshall L., Inhalable vaccine compositions and methods.
    상세보기
  34. Poole, Trent; Steiner, Solomon S., Inhalation apparatus.
    상세보기
  35. Ekwuribe,Nnochiri N.; Price,Christopher H.; Still,James Gordon; Filbey,Jennifer Ann; Ansari,Aslam M.; Odenbaugh,Amy L.; Radhakrishnan,Balasingam, Insulin conjugates for treating diabetes mellitus.
    상세보기
  36. Steiner, Solomon S.; Pohl, Roderike; Li, Ming; Hauser, Robert, Insulin formulations for rapid uptake.
    상세보기
  37. Glaser, Nichole, Insulin-dose calculator disk.
    상세보기
  38. Radhakrishnan, Balasingam; Aggarwal, Diti; Ferro, Michelle; James, Kenneth D.; Malkar, Navdeep B.; Miller, Mark A.; Puskas, Monica E.; Ekwuribe, Nnochiri N., Insulin-oligomer conjugates, formulations and uses thereof.
    상세보기
  39. Radhakrishnan, Balasingam; Aggarwal, Diti; Ferro, Michelle; James, Kenneth D.; Malkar, Navdeep B.; Miller, Mark A.; Puskas, Monica; Ekwuribe, Nnochiri N., Insulin-oligomer conjugates, formulations and uses thereof.
    상세보기
  40. Overfield, Dennis; Sahi, Carl R.; Adamo, Benoit; Kinsey, P. Spencer; McLean, Scott; Polidoro, John M.; Smutney, Chad C., Interactive apparatus and method for real-time profiling of inhalation efforts.
    상세보기
  41. Hermelin Victor M., Maximizing effectiveness of substances used to improve health and well being.
    상세보기
  42. Holakovsky, Holger; Lange, Lars; Steinzen, Maurice; Weiland, Felix; List, Klaus, Medicinal device with container.
    상세보기
  43. Schuy, Steffen; Meisenheimer, Martin; Witte, Florian, Method for coating a surface of a component.
    상세보기
  44. Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Method for delivery of monomeric or dimeric insulin complexed to diketopiperazine microparticles.
    상세보기
  45. Steiner, Solomon S.; Feldstein, Robert; Lian, Huiling; Rhodes, Christopher A.; Shen, Gregory S., Method for drug delivery to the pulmonary system.
    상세보기
  46. Wilson, Bryan R.; Grant, Marshall, Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
    상세보기
  47. Wilson, Bryan R.; Grant, Marshall, Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent.
    상세보기
  48. Gonda,Igor; Rubsamen,Reid M.; Farr,Stephen J., Method for treating diabetes mellitus in a patient.
    상세보기
  49. Hokenson, Mark; Oberg, Keith A., Method of drug formulation.
    상세보기
  50. Oberg, Keith A.; Sulner, Joseph; Grant, Marshall L., Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents.
    상세보기
  51. Oberg, Keith A.; Sulner, Joseph; Grant, Marshall L., Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents.
    상세보기
  52. Michaeli, Tamar H., Method of identification of inhibitors of PDE1C and methods of treatment of diabetes.
    상세보기
  53. Gonda,Igor; Rubsamen,Reid M.; Farr,Stephen J., Method of treating diabetes mellitus in a patient.
    상세보기
  54. Weiner, Howard L.; Eisenbarth, George; Hafler, David Allen; Zhang, Zhengyi, Method of treating or preventing Type 1 diabetes by oral administration of insulin.
    상세보기
  55. Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Methods and compositions for delivering peptides.
    상세보기
  56. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
    상세보기
  57. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
    상세보기
  58. Leone-Bay, Andrea; Houghten, Richard A.; Guarneri, Joseph J.; Stowell, Grayson W., Methods and compositions for treating pain.
    상세보기
  59. Vargas Rincon, Ricardo Alberto; Reiz, Joseph, Methods and compositions particularly for treatment of attention deficit disorder.
    상세보기
  60. Vargas Rincon, Ricardo Alberto; Reiz, Joseph, Methods and compositions particularly for treatment of attention deficit disorder.
    상세보기
  61. Still, James Gordon; Kosutic, Gordana, Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus.
    상세보기
  62. Ekwuribe,Nnochiri N.; Price,Christopher H.; Still,James Gordon; Filbey,Jennifer Ann, Methods of treating diabetes mellitus.
    상세보기
  63. Lee, Ronald D.; Vakily, Majid; Mulford, Darcy; Wu, Jing-Tao; Atkinson, Stuart, Methods of treating gastrointestinal disorders independent of the intake of food.
    상세보기
  64. Ekwuribe, Nnochiri N.; Price, Christopher H.; Ansari, Aslam M.; Odenbaugh, Amy L., Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same.
    상세보기
  65. Ekwuribe,Nnochiri N.; Price,Christopher H.; Ansari,Aslam M.; Odenbaugh,Amy L., Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same.
    상세보기
  66. Ekwuribe, Nnochiri N.; Price, Christopher H.; Ansari, Aslam M.; Odenbaugh, Amy L., Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same.
    상세보기
  67. Ekwuribe, Nnochiri N.; Price, Christopher H.; Ansari, Aslam M.; Odenbaugh, Amy L., Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same.
    상세보기
  68. Ekwuribe,Nnochiri N.; Price,Christopher H.; Ansari,Aslam M.; Radhakrishnan,Balasingam; Odenbaugh,Amy L., Mixtures of insulin drug-oligomer comprising polyalkylene glycol.
    상세보기
  69. Ekwuribe, Nnochiri N.; Price, Christopher H.; Ansari, Aslam M.; Radhakrishnan, Balasingam; Odenbaugh, Amy L., Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same.
    상세보기
  70. Ekwuribe,Nnochiri N.; Price,Christopher H.; Ansari,Aslam M.; Radhakrishnan,Balasingam; Odenbaugh,Amy L., Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same.
    상세보기
  71. Taneja, Rajneesh; Vakilynejad, Majid, Multiple PPI dosage form.
    상세보기
  72. Taneja, Rajneesh; Vakilynejad, Majid, Multiple PPI dosage form.
    상세보기
  73. Taneja, Rajneesh; Vakilynejad, Majid, Multiple PPI dosage form.
    상세보기
  74. Besseler, Jens; Holakovsky, Holger; Gorshoefer, Andreas; Gatz, Josef; Argauer, Herbert, Nebuliser with coding means.
    상세보기
  75. Bach, Alexander; Besseler, Jens; Holakovsky, Holger; Daelman, Manuel; Wuttke, Gilbert, Nebulizer.
    상세보기
  76. Bach, Alexander; Besseler, Jens; Holakovsky, Holger; Daelman, Manuel; Wuttke, Gilbert; Frenkel, Udo, Nebulizer.
    상세보기
  77. Bach, Alexander; Besseler, Jens; Holakovsky, Holger; Kaemper, Markus; Krakowka, Manuel; Wuttke, Gilbert, Nebulizer.
    상세보기
  78. Besseler, Jens; Herrmann, Frank; Holakovsky, Holger; Argauer, Herbert; Gatz, Josef; Gorshoefer, Andreas, Nebulizer.
    상세보기
  79. Besseler, Jens; Herrmann, Frank; Holakovsky, Holger; Argauer, Herbert; Gatz, Josef; Gorshoefer, Andreas, Nebulizer.
    상세보기
  80. Eicher, Joachim; Gatz, Josef; Herrmann, Frank; Hoelz, Hubert; Jung, Andree; Meisenheimer, Martin; Mueller, Markus; Von Schuckmann, Alfred; Wachtel, Herbert; Winkler, Robert Gerhard; Wuttke, Gilbert; Ziegler, Jochen, Nebulizer.
    상세보기
  81. Herrmann, Frank; Krenz, Holger; Endert, Guido; Wergen, Horst, Nebulizer.
    상세보기
  82. Holakovsky, Holger; Thoemmes, Ralf; Rohrschneider, Marc; Witte, Florian; Deane, Kevin Peter; Jennings, Douglas Ivan, Nebulizer.
    상세보기
  83. McGuinness Charlotte M. ; Burnside Beth A. ; Rudnik Edward M., Oral induction of tolerance to parenterally administered non-autologous polypeptides.
    상세보기
  84. Khedkar, Anand; Rangappa, Sharath Kumar Mallapura; Subramani, Ramesh; Dave, Nitesh; Radhakrishnan, Devesh; Shankar, Sundaresh; Chivukula, Sudheer; Ramakrishna, Ranjith; Murthy, Shanmugam Thandava; Pai, Harish Venkatraman; Sengupta, Nilanjan; Melarkode, Ramakrishnan; Iyer, Harish, Orally administrable solid pharmaceutical composition and a process thereof.
    상세보기
  85. Soltero, Richard; Radhakrishan, Balasingam; Ekwuribe, Nnochiri N.; Rehlaender, Bruce; Hickey, Anthony; Bovet, Li Li, Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith.
    상세보기
  86. Soltero,Richard; Radhakrishan,Balasingam; Ekwuribe,Nnochiri N.; Rehlaender,Bruce; Hickey,Anthony; Bovet,Li Li, Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith.
    상세보기
  87. Boss, Anders Hasager; Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Potentiation of glucose elimination.
    상세보기
  88. Boss, Anders Hasager; Steiner, Solomon S.; Woods, Rodney J.; Sulner, Joseph W., Potentiation of glucose elimination.
    상세보기
  89. Steiner, Solomon S.; Pohl, Roderike, Rapid acting and long acting insulin combination formulations.
    상세보기
  90. Steiner, Solomon S.; Pohl, Roderike, Rapid acting and long acting insulin combination formulations.
    상세보기
  91. Pohl,Roderike; Steiner,Solomon S., Rapid acting drug delivery compositions.
    상세보기
  92. Pohl, Roderike; Steiner, Solomon S., Rapid acting injectable insulin compositions.
    상세보기
  93. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
    상세보기
  94. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
    상세보기
  95. Kraft, Kelly Sullivan, Substituted diketopiperazine analogs for use as drug delivery agents.
    상세보기
  96. Richardson, Peter; Baughman, Robert A.; Potocka, Elizabeth; Boss, Anders Hasager; Petrucci, Richard, Use of ultrarapid acting insulin.
    상세보기

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