초록 ▼

A dual seal configuration for an aerosol canister containing a medicinal aerosol formulation. The canister includes a vial body and valve ferrule sealed by first and second sealing members to form a chamber that contains the medicinal aerosol formulation. The dual seal configuration reduces leakage

A dual seal configuration for an aerosol canister containing a medicinal aerosol formulation. The canister includes a vial body and valve ferrule sealed by first and second sealing members to form a chamber that contains the medicinal aerosol formulation. The dual seal configuration reduces leakage of contents, and is particularly helpful where the formulation includes hydrofluorocarbon propellant and an ethanol cosolvent. The first seal can be selected to be a barrier to the formulation components, while the second seal can be relatively more labile to such components.

대표청구항 ▼

[ I claim:] [1.] An aerosol canister for containing a medicinal aerosol formulation, comprising:a vial body, a first seal, a second seal, and a valve ferrule, whereinthe vial body has walls defining a vial opening, the valve ferrule occludes the vial opening, and the vial body, the first seal, and t

[ I claim:] [1.] An aerosol canister for containing a medicinal aerosol formulation, comprising:a vial body, a first seal, a second seal, and a valve ferrule, whereinthe vial body has walls defining a vial opening, the valve ferrule occludes the vial opening, and the vial body, the first seal, and the valve ferrule define a chamber, and the valve ferrule and vial body are in opposing sealing engagement with each of the first and second seals, and wherein the first seal provides a barrier to one or more medicinal aerosol formulation components to which the second seal is more labile to said one or more formulation components than the first seal and wherein the ferrule comprises a cylindrical skirt that extends along the exterior or interior of the vial body or along a complementary radial skirt.