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Peptide nucleic acids having amino acid side chains 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07H-021/00
  • C07K-005/00
  • C12Q-001/68
출원번호 US-0847095 (1997-05-01)
우선권정보 DK-0000510 (1992-04-15)
발명자 / 주소
  • Buchardt
  • deceased Ole,DKX
  • Egholm Michael
  • Nielsen Peter Eigil,DKX
  • Berg Rolf Henrik,DKX
  • Buchardt Dorte,DKX ITX legal representative of said Ole Buchardt
  • deceased
대리인 / 주소
    Woodcock Washburn Kurtz Mackiewicz & Norris LLP
인용정보 피인용 횟수 : 78  인용 특허 : 0

초록

A novel class of compounds, known as peptide nucleic acids, bind complementary DNA and RNA strands more strongly than the corresponding DNA or RNA strands, and exhibit increased sequence specificity and solubility. The peptide nucleic acids comprise ligands selected from a group consisting of natura

대표청구항

[ What is claimed is:] [1.] A compound having the formula: [ STR 3 ] wherein: L is selected from a group consisting of naturally-occurring nucleobases and non-naturally-occurring nucleobases;R.sup.7' is C.sub.1 -C.sub.8 alkylamine;E is COOH or an activated or protected derivative thereof; andZ is NH

이 특허를 인용한 특허 (78)

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