초록 ▼

The invention provides a method for the treatment and prevention of urinary incontinence in mammals, e.g., human males and females, especially nonpregnant female mammals, by administering a nitric oxide synthase substrate and/or nitric oxide donor, alone or in combination with an estrogenic agent an

The invention provides a method for the treatment and prevention of urinary incontinence in mammals, e.g., human males and females, especially nonpregnant female mammals, by administering a nitric oxide synthase substrate and/or nitric oxide donor, alone or in combination with an estrogenic agent and/or a progestational substance, with or without supplementation with an alpha-adrenergic agonist, beta-adrenergic receptor blocking agent, cholinergic-receptor blocking compound or a cholinergic-receptor-stimulating drug, as well as pharmaceutical compositions useful in practicing the methods of this invention.

대표청구항 ▼

[ What is claimed is:] [1.] A method of treating urinary incontinence symptoms in a female mammal, comprising administering to said female an effective amount of(a) a nitric oxide synthase substrate, a nitric oxide donor, or both, and, optionally, further administering an effective amount of(b) one

[ What is claimed is:] [1.] A method of treating urinary incontinence symptoms in a female mammal, comprising administering to said female an effective amount of(a) a nitric oxide synthase substrate, a nitric oxide donor, or both, and, optionally, further administering an effective amount of(b) one or more of a progestin, an estrogen or a partial estrogen agonist.