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Composition containing autologous thrombin blood fraction for use in a medical procedure 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/48
출원번호 US-7497172 (1996-11-15)
우선권정보 DK-0000830 (1992-06-24)
발명자 / 주소
  • Cederholm-Williams Stewart A.,GBX
  • Weis-Fogh Ulla,DKX
출원인 / 주소
  • Bristol-Myers Squibb Company
대리인 / 주소
    Furman, Jr.
인용정보 피인용 횟수 : 112  인용 특허 : 25

초록

The subject invention relates to the use of thrombin in a medical procedure in an animal. More specifically, the subject invention relates to such use of thrombin wherein the thrombin is a thrombin blood fraction is autologous to that animal.

대표청구항

[ What is claimed:] [1.] In a method for preparing a composition comprising materials released from platelets wherein said platelets are activated by thrombin, the improvement comprising thrombin that is derived from the same individual animal as said platelets.

이 특허에 인용된 특허 (25)

  1. Broly Herv (Houplines FRX) Ronfard Vincent (Lambersart FRX), Biological support for cell cultures constituted by plasma proteins coagulated by thrombin, its use in the preparation o.
    상세보기
  2. Rose Eric (Palisades NY) Dresdale Arthur (Plainfield NJ), Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma.
    상세보기
  3. Morse Brenda S. (Chamblee GA) Turner A. Denise (Dunwoody GA) McNally Robert T. (Marietta GA), Fibrin sealant delivery method.
    상세보기
  4. Sugitachi Akio (Koube JPX) Takagi Kunihiko (Kyoto JPX) Yabushita Yasunori (Yamatotakada JPX), Material for wound healing.
    상세보기
  5. Alterbaum Robert (101 West 15th St. New York NY 10011), Method and apparatus for use in preparation of fibrinogen from a patient\s blood.
    상세보기
  6. La Duca Frank M. (East Brunswick NJ), Method for clotting heparized blood by the addition of protamine, thrombin and snake venom.
    상세보기
  7. Linnau Yendra (Vienna ATX), Method of activating prothrombin.
    상세보기
  8. Kikuchi Masayoshi (Tsukuba JPX) Kunai Kenji (Ushiku JPX) Yamada Takafumi (Sagamihara JPX), Method of assaying fibrinogen, dry reagent therefor, and process for the preparation thereof.
    상세보기
  9. Kotitschke Ronald (Dreieich DEX) Stemberger Axel W. (Neubiberg DEX) Stephan Wolfgang (Dreieich DEX), Method of preparing a sterile plasma-protein solution containing fibrinogen and Factor XIII.
    상세보기
  10. Galanakis Dennis K. (Stony Brook NY), Method of preparing autologous plasma fibrin and application apparatus therefor.
    상세보기
  11. Kraus Michael (Frankfurt DEX) Mller Wolfgang (Oberursel DEX), Method of producing thrombin from factor II using calcium ions for the conversion on an anion exchanger.
    상세보기
  12. Cochrum Kent C. (Davis CA), Plasma and polymer containing surgical hemostatic adhesives.
    상세보기
  13. Schneider Morris D. (Knoxville TN), Platelet aggregating material from equine arterial tissue.
    상세보기
  14. Tanaka Kenji (Nara JPX) Miyano Kenmi (Osaka JPX) Nishimaki Hideo (Nara JPX) Iga Yoshiro (Osaka JPX), Process for heat treating thrombin.
    상세보기
  15. Michalski Catherine (Lille FRX) Dernis Dominique (Marquette lez Lille FRX), Process for preparing a human thrombin concentrate intended for therapeutic use.
    상세보기
  16. Crowley Carmel (Dundrum IEX) Sheehan Timothy G. (Ballincollig IEX) Ward Frederick G. (Kilpedder IEX), Process for the production of high purity thrombin.
    상세보기
  17. Silbering Steven B. (Forest Hills NY) Blythe ; Jr. Rowland P. (Washington MI) Nesbitt ; Jr. Russell U. (Somerville NJ) Fawzi Mahdi B. (Flanders NJ), Purified thrombin preparations.
    상세보기
  18. Altshuler John H. (Englewood CO), Ready-to-use bandage incorporating a coagulant composition and method of preparing same.
    상세보기
  19. Nishimaki Hideo (Kashihara JPX) Miyano Kenmi (Osaka JPX) Kameyama Shouju (Yawata JPX) Takechi Kazuo (Daito JPX) Iga Yoshiro (Osaka JPX), Stable aqueous thrombin solution.
    상세보기
  20. Sierra David H. (San Jose CA) Luck Edward E. (Menlo Park CA) Brown Dennis M. (Menlo Park CA), Surgical adhesive material.
    상세보기
  21. Proba Zbigniew (3067 Murray Avenue Chomedey ; Laval ; Quebec CAX) Brodniewicz Teresa (3067 Murray Avenue Chomedey ; Laval ; Quebec CAX H7V 2H2), Therapeutic grade thrombin produced by chromatography.
    상세보기
  22. Saferstein Lowell (Edison NJ) Wolf Stephen J. (Manville NJ), Thrombin aerosol.
    상세보기
  23. Silbering Steven B. (Forest Hills NY) Nesbitt Russell U. (Somerville NJ) Fawzi Mahdi B. (Flanders NJ), Thrombin preparations.
    상세보기
  24. Schwarz, Otto; Linnau, Yendra; Loblich, Franz; Seelich, Thomas, Tissue adhesive.
    상세보기
  25. Knighton David R. (Hudson WI), Wound healing agents derived from platelets.
    상세보기

이 특허를 인용한 특허 (112)

  1. Schmieding, Reinhold; Grafton, R. Donald, Accelerated healing with intraoperative combination of suture and autogenous blood components.
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  4. Leach, Michael D.; Chavarria, Jason, All-in-one means of separating blood components.
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  5. Leach, Michael D.; Chavarria, Jason, All-in-one means of separating blood components.
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  6. Dorian, Randel; Leach, Michael D., Apparatus and method for preparing platelet rich plasma and concentrates thereof.
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  23. Coelho Philip Henry ; Kingsley Phil ; Brausch Jim ; Godsey James H. ; Rock Gail,CAX, Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby.
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