초록 ▼

Systems and methods separate whole blood containing leukocytes in a first separation chamber into a first layer comprising red blood cells, a second layer comprising a suspension of platelets, and an interface between the first and second layers. The systems and methods convey the suspension of plat

Systems and methods separate whole blood containing leukocytes in a first separation chamber into a first layer comprising red blood cells, a second layer comprising a suspension of platelets, and an interface between the first and second layers. The systems and methods convey the suspension of platelets into a second separation chamber while simultaneously filtering the suspension of platelets to reduce the number of leukocytes. The systems and methods separate the filtered suspension of platelets in the second separation chamber into a platelet-rich concentrate and platelet-poor component.

대표청구항 ▼

[ I claim:] [4.] A method for obtaining a platelet-rich concentrate having a reduced number of leukocytes comprising(a) introducing whole blood containing leukocytes from a source at a selected first pumping rate into a first separation chamber,(b) separating the whole blood in the first separation

[ I claim:] [4.] A method for obtaining a platelet-rich concentrate having a reduced number of leukocytes comprising(a) introducing whole blood containing leukocytes from a source at a selected first pumping rate into a first separation chamber,(b) separating the whole blood in the first separation chamber into a first layer comprising a suspension of platelets, a second layer comprising red blood cells, and an interface between the first and second layers,(c) conveying the suspension of platelets at an outlet pumping rate from the first separation chamber into a second separation chamber while simultaneously filtering the suspension of platelets to reduce the number of leukocytes,(d) monitoring the location of the interface within the first separation chamber and varying the outlet pumping rate to maintain the interface within the first separation chamber while conveying the suspension of platelets from the first separation chamber, and(e) separating the filtered suspension of platelets in the second separation chamber into a platelet-rich concentrate and platelet-poor component.