초록 ▼

The invention provides a prepackaged dressing including dry particulate solids for forming a pourable, water-based natural or synthetic hydrocolloidal polyemeric gel to dress wounds. The gel contains a biologically active constituent. Liquid and dry, solid particulate components are separate and are

The invention provides a prepackaged dressing including dry particulate solids for forming a pourable, water-based natural or synthetic hydrocolloidal polyemeric gel to dress wounds. The gel contains a biologically active constituent. Liquid and dry, solid particulate components are separate and are mixed just before use. One dry constituent is the hydrocolloid which is contained in a compartment of a sealed container separate from moisture. After mixing with water, the dry hydrocolloid does not become fully hydrated immediately. The liquid component (water) provides a fluid consistency initially. At this stage, the admixture is sufficiently fluid in consistency to allow it to be poured or spread into a wound. Following application to the wound, the hydrated hydrocolloidal dispersion begins to solidify to form a solid, self-supporting flexible dressing structure consisting primarily of water, the hydrocolloid, as well as the biologically active constituent, e.g., an antibiotic, disinfectant, growth factor or the like in contact with the tissue of the animal or human patient. A gelling or cross-linking agent can also be used advantageously with some of the hydrocolloids. The resulting dressing becomes molded to the shape of the wound and contains a large quantity of moisture that will maintain the wound in a moist condition.

대표청구항 ▼

[ What is claimed is:] [1.] A pre-packaged wound dressing contained in a package for storing and mixing the dressing from which the dressing can be poured as a liquid and set up as a solid elastic body on the surface of a wound, said dressing comprising,about 3%-15% by weight of a natural or synthet

[ What is claimed is:] [1.] A pre-packaged wound dressing contained in a package for storing and mixing the dressing from which the dressing can be poured as a liquid and set up as a solid elastic body on the surface of a wound, said dressing comprising,about 3%-15% by weight of a natural or synthetic hydrocolloid polymer in dry particulate form contained in a compartment of said pouch,said polymer is a water soluble or water swellable hydrocolloid comprising a member selected from the group consisting of guar gum, locust bean gum, hydroxypropyl guar gum, polyglucomannan gum, cationic guar gum, anionic guar gum, alginate and xanthan gum,about 70%-95% by weight water contained in a second compartment of the package, the amount of said dry polymer relative to the amount of said water being effective to produce a liquid hydrocolloid dispersion of an initial viscosity which can be poured or spread onto a surface after said dry hydrocolloid polymer is mixed with said water and is capable of setting up to form a solid,said pre-packaged wound dressing including a biologically active substance for treating the wound,the water and the polymer being separated by a removable barrier that is a part of the package separating the polymer from the water to prevent communication between the dry hydrocolloid polymer and water for maintaining the hydrocolloid in the dry state,said dry hydrocolloid polymer, the biologically active substance and water being mixed together by rupturing or removing said barrier to form said liquid dispersion for being poured onto a wound or spread onto a wound after the water and polymer are mixed together, andafter application to the wound, said dispersion solidifies to form a gel which is an elastic solid resting upon the wound, said elastic solid gel has a lower surface that corresponds to the shape of the wound surface, said elastic solid gel protects the wound, maintains the wound in a moist condition and maintains said biologically active substance in contact with the wound to promote healing or patient comfort.