초록 ▼

A user activated iontophoretic device of the present invention includes an electrode assembly, an electrode reservoir and at least one drug reservoir. The device is divided or otherwise separated into at least two portions, with one portion containing the electrode reservoir and the other containing

A user activated iontophoretic device of the present invention includes an electrode assembly, an electrode reservoir and at least one drug reservoir. The device is divided or otherwise separated into at least two portions, with one portion containing the electrode reservoir and the other containing the drug reservoir, which may include a medication in a dry form. In one embodiment, the two portions are each contained in separate compartments of a pouch. In another embodiment, the portions are contained in a single compartment and divided by a barrier. A method of activating the device includes causing the two portions to come into electrical conducting contact with one another to at least partially hydrate one of the reservoirs. This can be accomplished, for example, by either folding the device to bring the two portions into contact with one another or simply by removing the barrier dividing the two portions. In the alternative, the device may include two separate portions which can be brought together to activate the device. In this way, the device is suitable for use to deliver a high dose efficiency, while providing a commercially suitable shelf-life.

대표청구항 ▼

[ What is claimed is:] [1.] A user activated device for iontophoretically delivering at least one medication to an applied area of a patient, comprising:an electrode assembly means for driving a medication into the applied area of the patient;wherein the electrode assembly means is situated in elect

[ What is claimed is:] [1.] A user activated device for iontophoretically delivering at least one medication to an applied area of a patient, comprising:an electrode assembly means for driving a medication into the applied area of the patient;wherein the electrode assembly means is situated in electrical communication with a first reservoir, having an electrolyte;a second reservoir containing a substantially non-hydrated medication to be delivered to the applied area of the patient;a first holding means for holding the electrode assembly means and the first reservoir, said first holding means including a means for maintaining the electrode assembly means in electrical communication with the first reservoir; a second holding means for holding the second reservoir and including a means for maintaining the second reservoir separate in relation to the first reservoir; the first holding means and the second holding means each having a release liner or barrier for sealing the first holding means and the second holding means so that prior to activation the second reservoir containing the medication is isolated from the first reservoir and maintained in a non-hydrated condition to prevent degradation and dilution of the medication contained in the second reservoir;wherein the device is activated by removing the release liner or barrier and placing the first reservoir in contact with the second reservoir, thereby to at least partially hydrate the medication contained in the second reservoir and to bring the first reservoir and the second reservoir into electrical communication with one another.