초록

A lyophilised collagen sponge used as an implant in osteitis and other bone cavities. The said sponge has dispersed therein antibacterially effective quantities of taurolidine and/or taurultam.

대표청구항 ▼

[ I claim:] [1.] In a method for the surgical treatment of a bacterially infected bone cavity with an implant in which the implant is introduced into the bone; wherein the improvement comprises implanting a sponge of uncompressed lyophilised cross-linked collagen into said bacterially infected bone

[ I claim:] [1.] In a method for the surgical treatment of a bacterially infected bone cavity with an implant in which the implant is introduced into the bone; wherein the improvement comprises implanting a sponge of uncompressed lyophilised cross-linked collagen into said bacterially infected bone cavity wherein said sponge is cross-linked solely with a physiologically acceptable cross-linking agent dispersed therein; all of said cross linking agent being an antibiotic selected from the group consisting of taurolidine and taurultam with the proviso that said cross-linking agent is the only crosslinking agent present in said sponge: and said cross-linking agent being present in an antibacterially-effective amount.