초록 ▼

The present invention relates generally to indwelling medical devices. In particular, there is provided a device constructed from permeable or nonpermeable material having a pharmacologically active ingredient layer surrounding the device, and an outer sheath which is permeable to the pharmacologica

The present invention relates generally to indwelling medical devices. In particular, there is provided a device constructed from permeable or nonpermeable material having a pharmacologically active ingredient layer surrounding the device, and an outer sheath which is permeable to the pharmacologically active ingredient. This construction provides a device that allows the pharmacologically active ingredient located between the catheter tube and the outer sheath to slowly diffuse through the outersheath and/or inner tube, thus inhibiting microbial infection on the outer surface and lumen of the catheter.

대표청구항 ▼

[ It is claimed:] [1.] An urethral catheter comprising:(i) a catheter;(ii) an outer sheath comprising a silicone compound concentric to and surrounding said catheter; and(iii) a pharmacologically active agent circumferentially located between said catheter and said outer sheath, wherein said pharmac

[ It is claimed:] [1.] An urethral catheter comprising:(i) a catheter;(ii) an outer sheath comprising a silicone compound concentric to and surrounding said catheter; and(iii) a pharmacologically active agent circumferentially located between said catheter and said outer sheath, wherein said pharmacologically active agent is embedded in a jacket of hydrophobic pharmacologically active agent-permeable material, wherein said outer sheath is permeable to said pharmacologically active agent to allow said pharmacologically active agent to slowly diffuse through the outer sheath, and also diffuse into the lumen of the catheter.