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| 국가/구분 | United States(US) Patent 등록 |
|---|---|
| 국제특허분류(IPC7판) |
|
| 출원번호 | US-0959599 (1997-10-29) |
| 발명자 / 주소 |
|
| 출원인 / 주소 |
|
| 대리인 / 주소 |
|
| 인용정보 | 피인용 횟수 : 265 인용 특허 : 0 |
A method for measuring the concentration of a chemical present in a blood stream of a mammalian subject is disclosed. The method involves contacting the subject's skin with a sensor assembly comprised of an ionically conducting material which contacts the skin, a working electrode which is in contac
A method for measuring the concentration of a chemical present in a blood stream of a mammalian subject is disclosed. The method involves contacting the subject's skin with a sensor assembly comprised of an ionically conducting material which contacts the skin, a working electrode which is in contact with the ionically conducting material which electrode has a catalytic surface and a mask having an opening therein. The mask is positioned between the skin and the working electrode. When the electrode is activated, chemical is transported through the skin and the ionically conductive material. The mask is positioned so that it blocks the flow into the catalytic surface except for flow which is substantially axially to the catalytic surface. Electrical signal generated at the working electrode is monitored over a period of time and correlated with a concentration of chemical present in the blood stream of the mammalian subject. The mask reduces or eliminates chemical signal which can radially transport toward the working electrode thereby reducing or eliminating edge effects making it possible to obtain a more accurate measurement.
[ What is claimed is:] [1.] A method of measuring a concentration of a chemical present in a bloodstream of a mammalian subject, comprising the steps of:contacting a mammalian subject's skin with a sensor assembly comprising;a) an ionically conductive material in contact with the skin;b) a working e
[ What is claimed is:] [1.] A method of measuring a concentration of a chemical present in a bloodstream of a mammalian subject, comprising the steps of:contacting a mammalian subject's skin with a sensor assembly comprising;a) an ionically conductive material in contact with the skin;b) a working electrode in contact with the ionically conductive material the working electrode having a catalytic surface; andc) a mask having an opening therein wherein the mask is positioned between the skin and the working electrode;transporting a chemical through the skin and ionically conductive material whereby the mask blocks flow to the catalytic surface except for flow substantially axial to the catalytic surface;monitoring an electrical signal generated at the working electrode by catalytic conversion into an electric signal at the catalytic surface of the working electrode;wherein the electrical signal generated at the working electrode over a given period of time is correlated with a concentration of chemical present in the bloodstream of the mammalian subject.
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