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Nucleic acid detection with energy transfer 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C09K-003/00
  • C07H-021/04
  • C12N-015/00
출원번호 US-0619724 (1996-05-20)
우선권정보 GB-0012106 (1994-06-16)
국제출원번호 PCT/GB94/020 (1994-09-23)
§371/§102 date 19960520 (19960520)
국제공개번호 WO-9508642 (1995-03-30)
발명자 / 주소
  • Sammes Peter George,GBX
  • Garman Andrew John,GBX
출원인 / 주소
  • Zeneca Limited, GB2
대리인 / 주소
    Cushman Darby & Cushman Intellectual Property Group of Pillsbury Madison & Sutro, LLP
인용정보 피인용 횟수 : 87  인용 특허 : 0

초록

A method for the detection of a nucleic acid analyte by complementary probe hybridisation and formation of a chelated lanthanide complex which, upon irradiation by light, results in a characteristic delayed luminescence emission.

대표청구항

[ We claim:] [1.] A method for detecting a nucleic acid analyte in a sample, which method comprises contacting the sample with (i) a binding entity complementary to the analyte and to which is attached a first partner of a ligand to metal energy transfer system, (ii) a lanthanide ion, and (iii) a se

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