초록 ▼

A method is provided for preparing a drug delivery material and device comprising cross-linking a biological polymer with a cross-linking agent and loading the cross-linked biopolymer with a bioactive agent. Preferred embodiments are disclosed wherein the drug delivery material is used in a catheter

A method is provided for preparing a drug delivery material and device comprising cross-linking a biological polymer with a cross-linking agent and loading the cross-linked biopolymer with a bioactive agent. Preferred embodiments are disclosed wherein the drug delivery material is used in a catheter securing, drug delivery device, in a wound dressing, and in a wound dressing for percutaneous catheters.

대표청구항 ▼

[ What is claimed is:] [1.] A percutaneous catheter wound dressing and drug-delivery device comprisingan elastomeric pad having a first radial slit extending from the edge of said pad to a central point proximate to the center of said pad, said pad comprising a cross-linked biopolymer and at least o

[ What is claimed is:] [1.] A percutaneous catheter wound dressing and drug-delivery device comprisingan elastomeric pad having a first radial slit extending from the edge of said pad to a central point proximate to the center of said pad, said pad comprising a cross-linked biopolymer and at least one bioactive agent reversibly bound to said cross-linked biopolymer, said bioactive agent being releasable from said cross-linked biopolymer in a controlled manner to a wound or to skin when said pad is placed in contact with said wound or skin. manner to a wound or to skin when said pad is placed in contact with said wound or skin.