$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Polymer-lipid microencapsulated gases for use as imaging agents

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-049/04
  • A61K-009/14
출원번호 US-0681710 (1996-07-29)
발명자 / 주소
  • Bernstein Howard
  • Straub Julie Ann
  • Brush Henry T.
  • Church Charles C.
출원인 / 주소
  • Acusphere, Inc.
대리인 / 주소
    Arnall Golden & Gregory, LLP
인용정보 피인용 횟수 : 44  인용 특허 : 86

초록

It has been discovered that the incorporation of gases, especially fluorinated gases such as perfluorocarbons, into microparticles formed from the combination of a natural or synthetic polymer and lipid have significantly enhanced echogenicity as compared with microparticles not including the lipid.

대표청구항

[ We claim:] [1.] A method for making microparticles for diagnostic imaging, wherein the microparticles are formed of a biocompatible polymer and have incorporated therein gas, the improvement comprising(a) incorporating into the polymer a hydrophobic compound by either dissolving the polymer and hy

이 특허에 인용된 특허 (86)

  1. Cook Edward J. (South Hamilton MA) Lagace Arthur P. (Newtonville MA), Apparatus for forming emulsions.
  2. Long ; Jr. David M. (San Diego CA), Biocompatible stable fluorocarbon emulsions for contrast enhancement and oxygen transport comprising 40-125% wt./volume.
  3. Long ; Jr. David M. (El Cajon CA), Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal.
  4. Gref Ruxandra (Nancy FRX) Minamitake Yoshiharu (Brookline MA) Langer Robert S. (Newton MA), Biodegradable injectable particles for imaging.
  5. Long ; Jr. David M. (El Cajon CA), Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport.
  6. Long ; Jr. David M. (El Cajon CA), Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport.
  7. Hilmann Juergen (Berlin DEX) Hoffmann Rolf-Ruediger (Berlin DEX) Muetzel Wolfgang (Berlin DEX) Zimmermann Ingfried (Berlin DEX), Carrier liquid solutions for the production of gas microbubbles, preparation thereof, and use thereof as contrast medium.
  8. Grinstaff Mark W. (Pasadena CA) Soon-Shiong Patrick (Los Angeles CA) Wong Michael (Champaign IL) Sandford Paul A. (Los Angeles CA) Suslick Kenneth S. (Champaign IL) Desai Neil P. (Los Angeles CA), Composition useful for in vivo delivery of biologics and methods employing same.
  9. Unger Evan C., Compositions of lipids and stabilizing materials.
  10. Widder Kenneth J. (Del Mar CA) Westkaemper Peter J. (San Diego CA), Concentrated stabilized microbubble-type ultrasonic imaging agent.
  11. Schweighardt Frank K. (Allentown PA) Kayhart Charles R. (Alburtis PA), Concentrated stable fluorochemical aqueous emulsions containing triglycerides.
  12. Feinstein Steven B. (295 Hasting Ave. Highland Park IL 60035), Contact agents for ultrasonic imaging.
  13. Cerny David (Chula Vista CA) Mills Gary J. (San Diego CA) Westkaemper Peter J. (San Diego CA), Continuous sonication method for preparing protein encapsulated microbubbles.
  14. Klaveness Jo (Oslo NOX) Priebe Hanno (Oslo NOX) Rongved Pal (Nesoddtanger NOX) Stubberud Lars (Sdertlje SEX), Contrast agents.
  15. Klaveness Jo (Oslo NOX) Rongved Pal (Nesoddtaugen NOX) Strande Per (Oslo NOX), Contrast agents.
  16. Klaveness Jo (Oslo NOX) Rongveo Pal (Hellvik NOX) Stubberud Lars (Sodertalje SEX), Contrast agents consisting of galactose particles.
  17. Feinstein Steven B. (295 Hasting Ave. Highland Park IL 60035), Contrast agents for ultrasonic imaging.
  18. Rssling Georg (Berlin DEX) Albayrak Celal (Berlin DEX) Rothe Matthias (Berlin DEX) Siegert Joachim (Berlin DEX), Contrast media synthesized from polyaldehydes.
  19. Berwing Klaus (Bad Nauheim DEX) Schlepper Martin (Bad Nauheim DEX), Contrast medium for ultrasonic examinations and process for its preparation.
  20. Langer Robert S. (Sommerville MA) Domb Abraham J. (Brookline MA) Laurencin Cato T. (Cambridge MA), Controlled drug delivery high molecular weight polyanhydrides.
  21. Schroder Ulf (Lund SEX) Salford Leif G. (Lund SEX), Diagnostic and contrast agent.
  22. Long ; Jr. David M. (San Diego CA), Dissolution of gas in a fluorocarbon liquid.
  23. Kaufman Robert J. (University City MO) Richard Thomas J. (University City MO), Emulsions of highly fluorinated organic compounds.
  24. Davis Stanley S. (Nottingham GBX) Wotton David E. M. (Bristol GBX), Emulsions of perfluorocarbons in aqueous media.
  25. Klaveness Jo (Oslo NOX) Priebe Hanno (Oslo NOX) Rongved Pl (Nesoddtauger NOX) Stubberud Lars (Sodertalje SEX), Flexible amphiphilic microbubbles for ultrasound.
  26. Kirkland W. Dean (El Cajon CA), Fluorocarbon contrast media for use with MRI and radiographic imaging.
  27. Long ; Jr. David M. (El Cajon CA), Fluorocarbon emulsions containing amino acid based anti-inflamatory agents and buffer systems.
  28. Yan Feng (Carouge CHX) Schneider Michel (Troinex CHX) Brochot Jean (Feigeres FRX), Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method.
  29. Lohrmann Rolf (La Jolla CA), Gas-filled microspheres with fluorine-containing shells.
  30. Quay Steven C. (Pacific Palisades CA), Gaseous ultrasound contrast media.
  31. Domb Abraham J. (Brookline MA) Langer Robert S. (Somerville MA), High molecular weight polyanhydride and preparation thereof.
  32. Klaveness Jo (Skoyen Terrasse NOX) Strande Per (Nordengveien NOX), Iodinated esters.
  33. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Ionophore containing liposomes for ultrasound imaging.
  34. Ryan Patrick J. (Worcester MA) Davis Michael A. (Westwood MA) Melchior Donald L. (Framingham MA), Lipisomes containing gas for ultrasound detection.
  35. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same.
  36. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same.
  37. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same.
  38. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same.
  39. Ryan, Patrick J.; Davis, Michael A.; Melchior, Donald L., Liposomes containing modified cholesterol for organ targeting.
  40. Schneider Michel (Troinex CHX) Yan Feng (Geneva CHX) Grenier ; deceased Pascal (late of Ambilly FRX by Nadine Garcel ; legal heir ) Puginier Jerome (Le Chable-Beaumont FRX) Barrau Marie-Bernadette (G, Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the prepa.
  41. Schneider Michel (Troinex CHX) Yan Feng (Genve CHX) Grenier ; deceased Pascal (late of Ambilly FRX by Nadine Garcel ; legal heir) Puginier Jrme (Le Chble-Beaumont FRX) Barrau Marie-Bernadette (Geneva, Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the prepa.
  42. Unger Evan C. (Tucson AZ), Low density microspheres and suspensions and their use as contrast agents for computed tomography and in other applicati.
  43. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Low density microspheres and their use as contrast agents for computed tomography.
  44. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Low density microspheres and their use as contrast agents for computed tomography.
  45. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Low density microspheres and their use as contrast agents for computed tomography.
  46. Unger Evan C. (Tucson AZ), Low density microspheres and their use as contrast agents for computed tomography, and in other applications.
  47. Desai Neil P. (Los Angeles CA) Soon-Shiong Patrick (Los Angeles CA) Sandford Paul A. (Los Angeles CA) Grinstaff Mark W. (Pasadena CA) Suslick Kenneth S. (Champaign IL), Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell.
  48. Long David M. (El Cajon CA), Magnetic resonance imaging with perfluorocarbon hydrides.
  49. Long David M. (El Cajon CA), Method for detecting abnormal cell masses in animals.
  50. Mathiowitz Edith (Brookline MA) Bernstein Howard (Cambridge MA) Morrel Eric (Needham MA) Schwaller Kirsten (Duxbury MA), Method for producing protein microspheres.
  51. Grinstaff Mark W. (Pasadena CA) Desai Neil P. (Los Angeles CA) Suslick Kenneth S. (Champaign IL) Soon-Shiong Patrick (Los Angeles CA) Sandford Paul A. (Los Angeles CA) Merideth Noma R. (Pacific Palis, Method for the preparation of fluorocarbon-containing polymeric shells for medical imaging.
  52. Tickner Ernest G. (Morgan Hill CA), Method of determining pressure within liquid containing vessel.
  53. Bichon Daniel,FRX ; Bussat Philippe,FRX ; Schneider Michel,CHX, Method of making polymeric gas or air filled microballoons for ultrasonic echography.
  54. Unger Evan C. (Tucson AZ) Fritz Thomas A. (Tucson AZ) Matsunaga Terry (Tucson AZ) Ramaswami VaradaRajan (Tucson AZ) Yellowhair David (Tucson AZ) Wu Guanli (Tucson AZ), Method of preparing gas and gaseous precursor-filled microspheres.
  55. Rasor Julia S. (Cupertino CA) Tickner Ernest G. (Gilroy CA), Method of production and use of microbubble precursors.
  56. Levene Harold B. (San Diego CA) Villapando Elaine (San Diego CA) Barnhart James L. (Encinitas CA) Widder Kenneth J. (Del Mar CA), Method of ultrasound imaging of the gastrointestinal tract.
  57. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Methods for providing localized therapeutic heat to biological tissues and fluids.
  58. Unger Evan C. (13365 E. Camino La Cebadilla Tucson AZ 85749), Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes.
  59. Quay Steven C. (Los Angeles CA), Methods for selecting and using gases as ultrasound contrast media.
  60. Rasor Julia S. (Cupertino CA) Tickner Ernest G. (Gilroy CA), Microbubble precursors and apparatus for their production and use.
  61. Rasor Julia S. (Cupertino CA) Tickner Ernest G. (Gilroy CA), Microbubble precursors and methods for their production and use.
  62. Klaveness Jo (Oslo NLX) Rongved Pal (Hellvik NLX) Stubberud Lars (Sodertalje NLX), Microbubble-generating contrast agents for ultrasound and magnetic resonance imaging.
  63. Grinstaff Mark W. (Pasadena CA) Desai Neil P. (Los Angeles CA) Suslick Kenneth S. (Champaign IL) Soon-Shiong Patrick (Los Angeles CA) Sandford Paul A. (Los Angeles CA) Merideth Noma R. (Pacific Palis, Non-fluorinated polymeric shells for medical imaging.
  64. Wolf Gerald L. (Winchester MA) Long David M. (El Cajon CA), Percutaneous lymphography using particulate fluorocarbon emulsions.
  65. Quay Steven C. (Los Angeles CA), Persistent gaseous bubbles as ultrasound contrast media.
  66. Domb Abraham J. (Brookline MA) Langer Robert S. (Somerville MA), Polyanhydrides with improved hydrolytic degradation properties.
  67. Ranney David F. (Dallas TX), Polychelating agents for image and spectral enhancement (and spectral shift).
  68. Charpiot Brigitte (Nice FRX) Greiner Jacques (Nice FRX) Le Blanc Maurice (Nice FRX) Manfredi Alexandre (Nice FRX) Riess Jean (Falicon FRX) Zarif Leila (Nice FRX), Polyhydroxylated and highly fluorinated compounds, their preparation and their use as surfactants.
  69. Grinstaff Mark W. (Pasadena CA) Desai Neil P. (Los Angeles CA) Suslick Kenneth S. (Champaign IL) Soon-Shiong Patrick (Los Angeles CA) Sandford Paul A. (Los Angeles CA) Merideth Noma R. (Pacific Palis, Polymeric shells for medical imaging prepared from synthetic polymers, and methods for the use thereof.
  70. Glajch Joseph L. (Nashua NH) Loomis Gary L. (Drexel Hill PA) Mahler Walter (Wilmington DE), Porous inorganic ultrasound contrast agents.
  71. Domb Abraham J. (Brookline MA) Langer Robert S. (Somerville MA), Preparation of anhydride copolymers.
  72. Sutton Andrew D. (Ruddington GB2) Johnson Richard A. (West Bridgford GB2) Senior Peter J. (Near Melbourne GB2) Heath David (The Park GB2), Preparation of diagnostic agents.
  73. Meinert Hasso (Ulm DEX) Mader Juergen (Ulm DEX), Process for separating mixtures of prefluorinated hydrocarbon compounds.
  74. Gardner David L. (Bellville OH), Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or e 상세보기
  • Schneider Michel (Troinex CHX) Brochot Jean (Feigeres FRX) Puginier Jerome (Le Chable-Beaumont FRX) Yan Feng (Meyrin CHX), Stable microbubble suspensions comprising saturated phospholipids for ultrasound echography.
  • Schneider Michel (Troinex CHX) Bichon Daniel (Montpellier FRX) Bussat Philippe (Collonges S/Saleve FRX) Puginier Jerome (Le Chable-Beaumont FRX) Hybl-Sutherland Eva (Wiesbaden DEX), Stable microbubbles suspensions injectable into living organisms.
  • Liversidge Gary G. (West Chester PA) Cundy Kenneth C. (Pottstown PA) Bishop John F. (Rochester NY) Czekai David A. (Honeoye Falls NY), Surface modified drug nanoparticles.
  • D\Arrigo Joseph S. (23A Brickyard Rd. Farmington CT 06032), Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures.
  • Unger Evan C. (Tucson AZ) Fritz Thomas A. (Tucson AZ) Matsunaga Terry (Tucson AZ) Ramaswami VaradaRajan (Tucson AZ) Yellowhair David (Tucson AZ) Wu Guanli (Tucson AZ), Therapeutic delivery systems related applications.
  • Erbel Raimund (Mainz DEX) Zotz Rainer (Mainz DEX) Krone Volker (Flrsheim DEX) Magerstdt Michael (Hofheim am Taunus DEX) Walch Axel (Frankfurt am Main DEX), Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents.
  • Rasor Ned S. (Cupertino CA) Hilmann Jurgen (Berlin DEX) Lange Lothar (Berlin DEX) Fritzsch Thomas (Berlin DEX) Siegert Joachim (Berlin DEX) Zimmermann Ingfried (Weiler DEX), Ultrasonic contrast medium comprising gas bubbles and solid lipophilic surfactant-containing microparticles and use ther.
  • Sato Ichiro (Tochigi JPX), Ultrasonic diagnosis apparatus.
  • Tickner Ernest G. (Morgan Hill CA) Rasor Ned S. (Santa Clara County CA), Ultrasonic image enhancement.
  • Feinstein Steven B. (295 Hasting Ave. Highland Park IL 60035), Ultrasonic imaging agent and method of preparation.
  • Quay Steven C. (Pacific Palisades CA), Ultrasound contrast media comprising perfluoropentane and perfluorohexane gas.
  • Roth Duane J. (La Jolla CA) Keipert Peter E. (San Diego CA) Faithfull Nicholas S. (Normanton by Bottesford OH GB2) Zuck Thomas F. (Cincinnati OH) Riess Jean G. (Nice FRX), Use of synthetic oxygen carriers to facilitate oxygen delivery.
  • 이 특허를 인용한 특허 (44)

    1. Bettinger, Thierry; Yan, Feng; Mehier-Humbert, Sophie; Frinking, Peter, Composition comprising gas-filled microcapsules for ultrasound mediated delivery.
    2. George, E. Victor; Wyeth, N. Convers; Green, Albert M.; Drobot, Adam T., Design, fabrication, testing, and conditioning of micro-components for use in a light-emitting panel.
    3. George,Edward Victor; Wyeth,Newell Convers; Green,Albert Myron, Design, fabrication, testing, and conditioning of micro-components for use in a light-emitting panel.
    4. Robert F. Mattrey, Diagnostic imaging of lymph structures.
    5. Sabel,Bernhard A.; Schroeder,Ulrike, Drug targeting system, method of its preparation and its use.
    6. Wheatley, Margaret A.; El-Sherif, Dalia, Echogenic polymer microcapsules and nanocapsules and methods for production and use thereof.
    7. Wheatley, Margaret A.; El-Sherif, Dalia, Echogenic polymer microcapsules and nanocapsules and methods for production and use thereof.
    8. Rossling Georg,DEX ; Albayrak Celal,DEX ; Rothe Matthias,DEX, Gaseous microparticles for ultrasonic diagnosis and process for their production.
    9. Ottoboni, Thomas B.; Tickner, E. Glenn; Short, Robert E.; Yamamoto, Ronald K., Hollow microspheres with controlled fragility for medical use.
    10. Heidlas, Jurgen; Zirzow, Karl-Heinz; Wiesmuller, Johann; Graefe, Jurgen, Homogenous water-free formulations containing glycerophospholipids and polar or lipophilic substances, method for the production thereof.
    11. Green, Albert Myron; Drobot, Adam Thomas; George, Edward Victor; Johnson, Roger Laverne; Wyeth, Newell Convers, Light-emitting panel and a method for making.
    12. Green, Albert Myron; Drobot, Adam Thomas; George, Edward Victor; Johnson, Roger Laverne; Wyeth, Newell Convers, Light-emitting panel and a method for making.
    13. Green, Albert Myron; Drobot, Adam Thomas; George, Edward Victor; Johnson, Roger Laverne; Wyeth, Newell Convers, Light-emitting panel and a method for making.
    14. Green,Albert Myron; Drobot,Adam Thomas; George,Edward Victor; Johnson,Roger Laverne; Wyeth,Newell Convers, Light-emitting panel and a method for making.
    15. Jin Tuo,CAX ; Pennefather Peter,CAX ; Lee Ping I., Lipid vesicle system.
    16. Green, Albert M.; George, E. Victor; Wyeth, N. Convers, Liquid manufacturing processes for panel layer fabrication.
    17. Green,Albert M.; George,E. Victor; Wyeth,N. Convers, Liquid manufacturing processes for panel layer fabrication.
    18. Green,Albert M.; George,E. Victor; Wyeth,N. Convers, Liquid manufacturing processes for panel layer fabrication.
    19. George, Edward Victor; Wyeth, Newell Convers; Green, Albert Myron, Manufacture of light-emitting panels provided with texturized micro-components.
    20. Drobot, Adam T.; Wyeth, N. Convers; George, E. Victor; Green, Albert M., Method and apparatus for addressing micro-components in a plasma display panel.
    21. Mesallum, Sameh, Method and apparatus for performing transesophageal cardiovascular procedures.
    22. Mesallum, Sameh, Method and apparatus for performing transesophageal cardiovascular procedures.
    23. Mesallum, Sameh, Method and apparatus for transesophageal cardiovascular procedures.
    24. George, Edward Victor; Johnson, Roger Laverne; Green, Albert Myron; Wyeth, Newell Convers, Method and system for energizing a micro-component in a light-emitting panel.
    25. Green, Albert Myron; Drobot, Adam Thomas; George, Edward Victor; Johnson, Roger Laverne; Wyeth, Newell Convers, Method for making a light-emitting panel.
    26. George,Edward Victor; Johnson,Roger Laverne; Green,Albert Myron; Wyeth,Newell Convers, Method for manufacturing a light-emitting panel.
    27. Wyeth, N. Convers; Green, Albert M.; George, E. Victor, Method for on-line testing of a light emitting panel.
    28. Johnson, Roger Laverne; Green, Albert Myron; George, Edward Victor; Wyeth, Newell Convers, Method for testing a light-emitting panel and the components therein.
    29. Mesallum, Sameh; Bleck, James H., Methods and apparatus for transesophageal microaccess surgery.
    30. George, Edward Victor; Drobot, Adam Thomas; Johnson, Roger Laverne; Green, Albert Myron; Wyeth, Newell Convers, Micro-component for use in a light-emitting panel.
    31. Ottoboni, Thomas B.; Short, Robert E.; Gabe, Jeffrey D., Nanobubbles useful as an ultrasonic contrast agent for the lymphatic system.
    32. Perumal, Omathanu P.; Podaralla, Satheesh K.; Averineni, Ranjith Kumar, Polymer conjugated protein micelles.
    33. Perumal, Omathanu P.; Podaralla, Satheesh K.; Averineni, Ranjith Kumar, Polymer conjugated protein micelles.
    34. George, Edward Victor; Johnson, Roger Laverne; Green, Albert Myron; Wyeth, Newell Convers, Socket for use with a micro-component in a light-emitting panel.
    35. George, Edward Victor; Johnson, Roger Laverne; Green, Albert Myron; Wyeth, Newell Convers, Socket for use with a micro-component in a light-emitting panel.
    36. George, Edward Victor; Johnson, Roger Laverne; Green, Albert Myron; Wyeth, Newell Convers, Socket for use with a micro-component in a light-emitting panel.
    37. George,Edward Victor; Johnson,Roger Laverne; Green,Albert Myron; Wyeth,Newell Convers, Socket for use with a micro-component in a light-emitting panel.
    38. Emanuel, Noam; Neuman, Moshe; Barak, Shlomo, Sustained-release drug carrier composition.
    39. Emanuel, Noam; Neuman, Moshe; Barak, Shlomo, Sustained-release drug carrier composition.
    40. Emanuel, Noam; Rosenfeld, Yosef, Sustained-release nucleic acid matrix compositions.
    41. Emanuel, Noam; Rosenfeld, Yosef, Sustained-release nucleic acid matrix compositions.
    42. Walovitch, Richard; Bernstein, Howard; Chickering, Donald; Straub, Julie, Ultrasound contrast agent dosage formulation.
    43. Walovitch, Richard; Bernstein, Howard; Chickering, III, Donald; Straub, Julie, Ultrasound contrast agent dosage formulation.
    44. George, E. Victor; Green, Albert M.; Wyeth, N. Convers, Use of printing and other technology for micro-component placement.
    섹션별 컨텐츠 바로가기

    AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

    AI-Helper 아이콘
    AI-Helper
    안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
    ※ AI-Helper는 부적절한 답변을 할 수 있습니다.

    선택된 텍스트