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Gels for encapsulation of biological materials 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/48
  • B05D-007/00
  • C12N-011/00
  • C12N-011/02
출원번호 US-0467815 (1995-06-06)
발명자 / 주소
  • Hubbell Jeffrey A.
  • Pathak Chandrashekhar P.
  • Sawhney Amarpreet S.
  • Desai Neil P.
  • Hill Jennifer L.
  • Hossainy Syed F. A.
출원인 / 주소
  • Board of Regents, The university of Texas System
대리인 / 주소
    Arnall, Golden & Golden, LLP
인용정보 피인용 횟수 : 80  인용 특허 : 0

초록

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particula

대표청구항

[ We claim:] [1.] A substrate comprising a surface having a polymeric coating thereon formed by free radical polymerization of a biocompatible, water soluble macromer having covalently linked to it at least two free radical polymerizable substituents,wherein the coating is formed on the substrate su

이 특허를 인용한 특허 (80)

  1. Sawhney, Amarpreet S.; Ransone, II, William H., Adhesive hydrogels for ophthalmic drug delivery.
  2. Bezwada, Rao S., Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof.
  3. Bezwada, Rao S, Bioabsorbable surgical articales or components thereof.
  4. Kiser, Patrick F.; Thomas, Allen A., Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments.
  5. Campbell, Patrick; Sawhney, Amarpreet S., Biomaterials for track and puncture closure.
  6. Keenan,Steve, Blood-tight implantable textile material and method of making.
  7. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L.; Hossainy, Syed F. A., Coating substrates by polymerizing macromers having free radical-polymerizable substituents.
  8. Bezwada, Rao S., Control release of biologically active compounds from multi-armed oligomers.
  9. Bezwada, Rao S, Controlled release of biologically active compounds.
  10. Bezwada, Rao S, Controlled release of biologically active compounds.
  11. Bezwada, Rao S., Controlled release of biologically active compounds.
  12. Bezwada, Rao S, Controlled release of biologically active compounds from multi-armed oligomers.
  13. Jarrett, Peter; El-Hayek, Rami; Sawhney, Amarpreet S.; Guedez, Sarah, Drug delivery systems and applications.
  14. Jarrett, Peter; Bassett, Michael; Blizzard, Charles D.; Sawhney, Amarpreet S., Drug delivery through hydrogel plugs.
  15. Sawhney, Amarpreet S.; Jarrett, Peter; Bassett, Michael; Blizzard, Charles, Drug delivery through hydrogel plugs.
  16. Constant, Michael; Garretson, Josh; Cruise, Gregory M., Embolic devices.
  17. Constant, Michael; Keeley, Edward Michael; Garretson, Joshua; Cruise, Gregory M., Embolic devices.
  18. Constant, Michael; Keeley, Edward Michael; Garretson, Joshua; Cruise, Gregory M.; Graczyk, Wendy, Embolic devices.
  19. Cruise, Gregory M.; Constant, Michael J.; Tran, Terrance, Embolization device constructed from expansile polymer.
  20. Cruise, Gregory M.; Constant, Michael J.; Tran, Terrance, Embolization device constructed from expansile polymer.
  21. Cruise, Gregory M.; Constant, Michael J.; Tran, Terrance, Embolization device constructed from expansile polymer.
  22. Cruise, Gregory M.; Constant, Michael; Tran, Terrance; Gulachenski, Joseph, Embolization device constructed from expansile polymer.
  23. Cruise, Gregory M.; Constant, Michael; Tran, Terrance; Gulachenski, Joseph, Embolization device constructed from expansile polymer.
  24. Keeley, E. Michael; Cruise, Gregory M.; Constant, Michael J.; Warner, Sheila; Walker, Maricela, Embolization device constructed from expansile polymer.
  25. C. Patrick Reynolds ; Tomas Frgala CZ, Fluorescence digital imaging microscopy system.
  26. Reynolds, C. Patrick; Frgala, Tomas, Fluorescence digital imaging microscopy system.
  27. Desai, Neil P.; Tao, Chunlin; Yang, Andrew; Louie, Leslie; Soon-Shiong, Patrick, Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof.
  28. Bezwada, Rao S, Functionalized biodegradable triclosan monomers and oligomers for controlled release.
  29. Bezwada, Rao S, Functionalized biodegradable triclosan monomers and oligomers for controlled release.
  30. Bezwada, Rao S., Functionalized biodegradable triclosan monomers and oligomers for controlled release.
  31. Bezwada, Rao S, Functionalized phenolic compounds and polymers therefrom.
  32. Bezwada, Rao S., Functionalized sinapic acid and methyl sinapate.
  33. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
  34. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hossainy, Syed F. A., Gels for encapsulation of biological materials.
  35. Hubbell,Jeffrey A.; Pathak,Chandrashekhar P.; Sawhney,Amarpreet S.; Desai,Neil P.; Hossainy,Syed F. A., Gels for encapsulation of biological materials.
  36. Cruise, Gregory M.; Constant, Michael J.; Keeley, Edward Michael; Tran, Terrance T., Hydrogel filaments for biomedical uses.
  37. Sawhney, Amarpreet S.; Ransone, II, William H., Hydrogel polymeric compositions and methods.
  38. Sawhney, Amarpreet S.; Ransone, II, William H., Hydrogel polymeric compositions and methods.
  39. Sawhney, Amarpreet S.; Ransone, II, William H., Hydrogel polymeric compositions and methods.
  40. Bezwada, Rao S, Hydrolysable linkers and cross-linkers for absorbable polymers.
  41. Bezwada, Rao S, Hydrolysable linkers and cross-linkers for absorbable polymers.
  42. Bezwada, Rao S, Hydrolysable linkers and cross-linkers for absorbable polymers.
  43. Bezwada, Rao S., Hydrolysable linkers and cross-linkers for absorbable polymers.
  44. Waller, Jr., Clinton P.; Weiss, Douglas E., Hydrophilic porous substrates.
  45. Waller, Jr., Clinton P.; Weiss, Douglas E., Hydrophilic porous substrates.
  46. Hubbell,Jeffrey A.; Pathak,Chandrashekhar P.; Sawhney,Amarpreet S.; Desai,Neil P.; Hill,Jennifer L.; Hossainy,Syed F. A., Implantable substrate coated with a macromer having free radical polymerizable substituents.
  47. Cruise, Gregory M.; Constant, Michael J.; Keeley, Edward Michael; Tran, Terrance T., Implantation devices including hydrogel filaments.
  48. Scharp,David; Latta,Paul; Yue,Chengyun; Yu,Xiaojie; Hubbell,Jeffrey Alan, Implantation of encapsulated biological materials for treating diseases.
  49. Greenawalt, Keith E., Making a soft tissue prosthesis for repairing a defect of an abdominal wall or a pelvic cavity wall.
  50. Seliktar, Dror; Almany, Liora, Matrix composed of a naturally-occurring protein backbone cross linked by a synthetic polymer and methods of generating and using same.
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  53. Seliktar, Dror; Almany, Liora, Matrix composed of a naturally-occurring protein backbone cross linked by a synthetic polymer and methods of generating and using same.
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  55. Krause, Bernd; Zweigart, Carina, Membranes having improved performance.
  56. Krause, Bernd; Zweigart, Carina; Behr, Heinrich, Membranes having improved performance.
  57. Jarrett, Peter; El Hayek, Rami; Bassett, Michael; Biggins, James, Method for applying flowable hydrogels to a cornea.
  58. Hippensteel, Gregory M.; Peek, Lawrence F.; Anderson, Jeffrey P.; Gorhe, Devendra; Allen, Steve M., Method for bonding a tantalum structure to a cobalt-alloy substrate.
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  60. Beech, Robert P.; Reed, Thomas D.; Patzig, Robert, Methods and compositions for diagnosing disease.
  61. Cohn,Daniel; Pines,Eli; Hotovely,Anna, Methods and compositions for reducing or eliminating post-surgical adhesion formation.
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  63. Sawhney, Amarpreet S., Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels.
  64. Sawhney, Amarpreet S., Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels.
  65. Seliktar, Dror; Almany, Liora, PEGylated fibrinogen precursor molecule.
  66. Seliktar, Dror; Almany, Liora, Pegylated fibrinogen precursor molecule.
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  68. Cohn, Daniel; Stern, Theodor; Levi, Avraham, Polymeric compositions.
  69. Constant, Michael; Cruise, Gregory M.; Chen, Samuel, Polymers.
  70. Anderson, Jeffrey P.; Popoola, Oludele, Process for forming a ceramic layer.
  71. Anderson, Jeffrey P.; Popoola, Oludele O., Process for forming a ceramic layer.
  72. Cohn, Daniel; Levi, Avraham, Reverse thermal gellation polymer of chain-extended optional polyester-terminated PEO-PPO-PEO.
  73. Greenawalt, Keith E., Soft tissue prosthesis for repairing a defect of an abdominal wall or a pelvic cavity wall.
  74. Zhang, Kai; Buehler, Daniel; Brinkerhuff, Hallie E.; Hawkins, Michael E.; Klabunde, Ralf, Spacer with a coating thereon for use with an implant device.
  75. Sawhney, Amarpreet S.; Bennett, Steven L.; Pai, Suresh S.; Sershen, Scott R.; Co, Fred H., Superabsorbent, freeze dried hydrogels for medical applications.
  76. Peyman Gholam A., Therapeutic contact lens comprising living cells within a matrix.
  77. Merenick, Bethany Lynn; Beech, Robert P.; Reed, Thomas D.; Tretiakova, Anna P.; Peterson, Richard E., Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof.
  78. Ameer,Guillermo A.; Crumpler,Eric T.; Langer,Robert S., Transdermal thermal polymerization.
  79. Jeffrey A. Hubbell CH; Chandrashekhar P. Pathak ; Amarpreet Sawhney ; Neil Desai ; Syed Hossainy ; Jennifer L. Hill-West, Treating medical conditions by polymerizing macromers to form polymeric materials.
  80. Bezwada, Rao S, Unsymmetrical aromatic ether diacids and absorbable polymers therefrom.
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