$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/18
출원번호 US-0696566 (1996-08-16)
발명자 / 주소
  • Matthews William
  • Austin Timothy W.
출원인 / 주소
  • Genentech, Inc.
대리인 / 주소
    Svoboda
인용정보 피인용 횟수 : 103  인용 특허 : 34

초록

Uses for Wnt polypeptides in hematopoiesis are disclosed. In particular, in vitro and in vivo methods for enhancing proliferation or differentiation of a hematopoietic stem/progenitor cell using a Wnt polypeptide, and optionally another cytokine, are described.

대표청구항

[ What is claimed is:] [1.] A method for enhancing proliferation or differentiation of a hematopoietic stem/progenitor cell comprising exposing the cell to an amount of isolated Wnt polypeptide which is effective for enhancing proliferation or differentiation of the cell.

이 특허에 인용된 특허 (34)

  1. Ayers John S. (Palmerston North NZX) Bethell Geoffrey S. (Palmerston North NZX) Hancock William S. (Palmerston North NZX) Hearn Milton T. W. (Dunedin North NZX), Activated matrix and method of activation.
  2. Iwashita Yuji (Kawasaki JPX) Ajisaka Katsumi (Yokohama JPX), Blood substitute containing modified hemoglobin.
  3. Jaworek Dieter (Weilheim ; Upper Bavaria DT) Nelbock-Hochstetter Michael (Tutzing DT) Beaucamp Klaus (Tutzing DT) Bergmeyer Hans Ulrich (Tutzing DT) Botsch Karl-Heinz (Bernried DT), Carrier-bound protein prepared by reacting the protein with an acylating or alkylating compound having a carrier-bonding.
  4. Darfler Frederick J. (Derwood MD), Cell culture medium with antioxidant.
  5. Nakagawa Yasushi (Kawanishi JPX) Ito Takashi (Osaka JPX), Chemically modified protein with polyethyleneglycol.
  6. Mitra Gautam (Kensington CA), Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer.
  7. Brake Anthony J. (Berkeley CA) Van Den Berg Johan A. (Ad Reeuwijk NLX), DNA constructs containing a Kluyveromyces alpha factor leader sequence for directing secretion of heterologous polypepti.
  8. Hirohara Hideo (Ibaraki JPX) Nabeshima Shigeyasu (Ibaraki JPX) Fujimoto Masanori (Ibaraki JPX) Nagase Tsuneyuki (Takatsuki JPX), Enzyme immobilization with pullulan gel.
  9. Iwasaki Keiji (Kawasaki JPX) Iwashita Yuji (Kawasaki JPX) Okami Taketoshi (Yokohama JPX), Hemoglobin combined with a poly(alkylene oxide).
  10. David Gary S. (La Jolla CA) Greene Howard E. (Carlsbad CA), Immunometric assays using monoclonal antibodies.
  11. Van den Berg Johan A. (Ad Reeuwijk NLX) Van Ooyen Albert J. J. (AR Voorburg NLX) Rietveld Krijn (TL Vlaardingen NLX), Kluyveromyces as a host strain.
  12. Ryan, Patrick J.; Davis, Michael A.; Melchior, Donald L., Liposomes containing modified cholesterol for organ targeting.
  13. Woodle Martin C. (Menlo Park CA) Martin Francis J. (San Francisco CA) Yau-Young Annie (Los Altos CA) Redemann Carl T. (Walnut Creek CA), Liposomes with enhanced circulation time.
  14. Litman David J. (Palo Alto CA) Harel Zvi (Stanford CA) Ullman Edwin F. (Atherton CA), Macromolecular environment control in specific receptor assays.
  15. Karin Michael (Los Angeles CA), Mammalian metallothionein promoter system.
  16. Mather Jennie P. (Millbrae CA) Tsao Mary C. (Burlingame CA), Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins.
  17. Royer Garfield P. (Worthington OH), Modifying enzymes with polyethylene glycol and product produced thereby.
  18. Davis Frank F. (19 Farmingdale Rd. East Brunswick NJ 08816) Van Es Theodorus (313 Overbrook Rd. Piscataway NJ 08854) Palczuk Nicholas C. (45 W. Franklin St. Bound Brook NJ 08805), Non-immunogenic polypeptides.
  19. Beckwith Jonathan R. (Cambridge MA) Strauch Kathryn L. (Brighton MA), Periplasmic protease mutants of Escherichia coli.
  20. Drayna Dennis T. (San Francisco CA) Eaton Dan L. (San Rafael CA), Plasma carboxypeptidase.
  21. Shimizu Kimihiro (Yoshikawa JPX) Nakahara Tsuguji (Tokyo JPX) Kinoshita Taketoshi (Koshigaya JPX) Takatsuka Jun (Kawasaki JPX) Igarashi Michiko (Musashino JPX), Plasminogen activator derivatives.
  22. Hildebrand Dietrich (Odenthal DEX) Gribnau Thomas (Weezenhof NLX), Polymeric carrier bound ligands.
  23. Capon Daniel J. (San Mateo CA) Lawn Richard M. (San Francisco CA) Levinson Arthur D. (Hillsborough CA) Vehar Gordon A. (San Carlos CA) Wood William I. (San Mateo CA), Preparation of functional human factor VIII in mammalian cells using methotrexate based selection.
  24. Hodgins Leonard T. (New York NY) Finlay Thomas H. (Ridgewood NJ) Johnson Alan J. (New York NY), Preparation of trichloro-s-triazine activated supports for coupling ligands.
  25. Sugimoto Kaname (Okayama JPX) Hayashibara Yasushi (Okayama JPX), Process for the production of human erythropoietin.
  26. Axel Richard (New York NY) Wigler Michael H. (Cold Spring Harbor NY) Silverstein Saul J. (Irvington NY), Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials.
  27. Cleveland William L. (New York NY) Erlanger Bernard F. (Whitestone NY), Protein-free culture medium.
  28. Howley Peter M. (Bethesda MD) Sarver Nava (Bethesda MD) Law Ming-Fan (Germantown MD), Recombinant DNA process utilizing a papilloma virus DNA as a vector.
  29. Cabilly Shmuel (Monrovia CA) Heyneker Herbert L. (Burlingame CA) Holmes William E. (Pacifica CA) Riggs Arthur D. (La Verne CA) Wetzel Ronald B. (San Francisco CA), Recombinant immunoglobin preparations.
  30. Cartaya Oscar A. (125 Pleasant St. ; Apt. #401 Brookline MA 02146), Serum-free cell culture media.
  31. Baker, Paul E., Serum-free cell culture medium and process for making same.
  32. Kumar Sudhir (18901 Springfield Flossmoor IL 60422), Serum-free, synthetic, completely chemically defined tissue culture media.
  33. Regen Steven L. (Milwaukee WI), Synthetic phosphatidyl cholines useful in forming liposomes.
  34. Segal David M. (Rockville MD) Perez Pilar (Bethesda MD), Target specific cross-linked heteroantibodies.

이 특허를 인용한 특허 (103)

  1. Abbot, Stewart; Edinger, James W.; Francki, Aleksandar; Kaplunovsky, Aleksandr; Jankovic, Vladimir; Labazzo, Kristen; Law, Eric; Padliya, Neerav D.; Paredes, Jennifer; Wang, Jia-Lun, Amnion derived adherent cells.
  2. Abbot, Stewart; Edinger, James W.; Francki, Aleksandar; Kaplunovsky, Aleksandr; Jankovic, Vladimir; Labazzo, Kristen; Law, Eric; Padliya, Neerav; Paredes, Jennifer; Wang, Jia-Lun, Amnion derived adherent cells.
  3. Abbot, Stewart; Edinger, James W.; Francki, Aleksandar; Hariri, Robert J.; Jankovic, Vladimir; Kaplunovsky, Aleksandr; Labazzo, Kristen; Law, Eric; Padliya, Neerav D.; Paredes, Jennifer; Wang, Jia-Lun, Angiogenesis using placental stem cells.
  4. Orlow,Seth J.; Manga,Prashiela; Staleva,Liliana, Assay for melanogenesis.
  5. Keller, Gordon M; Kouskoff, Valerie; Kubo, Atsushi; Fehling, Hans Joerg, Cell population enriched for endoderm cells.
  6. Heidaran, Mohammad; Wang, Jia-Lun; Ye, Qian; Zeitlin, Andrew; Delaney, Colleen Suzanne, Co-culture of placental stem cells and stem cells from a second source.
  7. Heidaran, Mohammad; Wang, Jia-Lun; Ye, Qian; Zeitlin, Andrew; Dulaney, Colleen Suzanne, Co-culture of placental stem cells and stem cells from a second source.
  8. Nusse, Roeland; Willert, Karl H., Compositions of active WNT protein.
  9. Nusse, Roeland; Willert, Karl H., Compositions of active Wnt protein.
  10. Nusse, Roeland; Willert, Karl H., Compositions of active Wnt protein.
  11. Nusse, Roeland; Willert, Karl H., Compositions of active Wnt protein.
  12. Nusse, Roeland; Willert, Karl H., Compositions of active Wnt protein.
  13. Nusse,Roeland; Willert,Karl H., Compositions of active Wnt protein.
  14. Nusse,Roeland; Willert,Karl H., Compositions of active Wnt protein.
  15. Lang, Richard, Compositions useful for and methods of modulating angiogenesis.
  16. Eichner, Wolfram; Schimmel, Martin; Hacket, Frank; Kraus, Elmar; Zander, Norbert; Frank, Ronald; Conradt, Harald; Langer, Klaus; Orlando, Michele; Sommermeyer, Klaus, Conjugates of hydroxyalkyl starch and a protein.
  17. Eichner, Wolfram; Orlando, Michele; Zander, Norbert; Conradt, Harald S.; Hacket, Frank; Langer, Klaus; Frank, Ronald, Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination.
  18. Orlando, Michele; Hemberger, Jurgen; Sommermeyer, Klaus; Eichner, Wolfram; Frie, Sven; Lutterbeck, Katharina; Jungheinrich, Cornelius; Scharpf, Roland, Coupling low-molecular substances to a modified polysaccharide.
  19. Hemberger, Jurgen; Orlando, Michele; Sommermeyer, Klaus; Eichner, Wolfram; Frie, Sven; Lutterbeck, Katharina; Jungheinrich, Cornelius; Scharpf, Roland, Coupling proteins to a modified polysaccharide.
  20. Peled, Tony; Steinhardt, Yair, Culturing of mesenchymal stem cells with FGF4 and nicotinamide.
  21. Hariri, Robert J., Cytotherapeutics, cytotherapeutic units and methods for treatments using them.
  22. Jones, Stephen N.; Liang, Huiling; Pihan, German, Diagnosing and treating hematopoietic cancers.
  23. Hariri,Robert J., Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells.
  24. Peled, Tony; Frei, Gabi M., Enhancement of natural killer (NK) cell proliferation and activity.
  25. Abbot, Stewart; Karasiewicz-Mendez, Kathy E.; Voskinarian-Berse, Vanessa; Zhang, Xiaokui, Enhancement of placental stem cell potency using modulatory RNA molecules.
  26. Rubin, Jeffrey S.; Üren, Aykut; Cumberledge, Susan; Reichsman, Frieda, Fragments of secreted frizzled related protein.
  27. Rudnicki, Michael; Seale, Patrick; Polesskaya, Anna; Fortin, Anouk, Growth and differentiation of adult muscle stem cells with activators or inhibitors of Wnt signaling.
  28. Conradt, Harald S.; Grabenhorst, Eckart; Nimtz, Manfred; Zander, Norbert; Frank, Ronald; Eichner, Wolfram, Hasylated polypeptides.
  29. Zander, Norbert; Conradt, Harald; Eichner, Wolfram, Hydroxyalkyl starch derivatives.
  30. Basile, Lena A., IL-12 formulations for enhancing hematopoiesis.
  31. Paludan, Casper; Edinger, James W.; Harbacheuski, Ryhor; Murray, RoseAnn; Hariri, Robert J., Immunomodulation using placental stem cells.
  32. Paludan, Casper; Edinger, James; Harbacheuski, Ryhor; Murray, RoseAnn; Hariri, Robert J., Immunomodulation using placental stem cells.
  33. Paludan, Casper; Edinger, James; Harbacheuski, Ryhor; Murray, RoseAnn; Hariri, Robert J., Immunomodulation using placental stem cells.
  34. Uemura, Masaru; Yuge, Rui, Method and apparatus for cultivating multipotent stem cells.
  35. Chen, Tingchao; Zhao, Yi; Anderson, W. French, Method for bone marrow preservation or recovery.
  36. Sulkowski, Eugene; Chadha, Kailash C.; Kawinski, Elzbieta, Method for detecting PSA and its molecular forms using thiophilic gel on magnetic beads.
  37. El-Tayar, Nabil; Roberts, Michael J.; Harris, Milton; Sawlivich, Wayne, Method for producing polyol-IFN-β conjugate.
  38. Chen, Tingchao; Zhao, Yi; Anderson, W. French, Method for treating deficiency in hematopoiesis.
  39. Heidaran, Mohammad A.; Zhang, Xiaokui; Kang, Lin; Zeitlin, Andrew; Voskinarian-Berse, Vanessa R.; Abbott, Stewart Ernest, Method of producing erythrocytes.
  40. Poueymirou, William; DeChiara, Thomas M.; Auerbach, Wojtek; Frendewey, David; Valenzuela, David M., Methods and compositions for generating a mouse.
  41. Poueymirou, William; DeChiara, Thomas M.; Auerbach, Wojtek; Frendewey, David; Valenzuela, David M., Methods and compositions for generating a mouse.
  42. Abramson, Sascha D.; Guelakis, Marian; Heidaran, Mohammad A.; Labazzo, Kristen; Yaccoby, Shmuel, Methods and compositions for treatment of bone defects with placental cell populations.
  43. Orlow, Seth J.; Hall, Andrea; Manga, Prashiela, Methods and compositions that affect melanogenesis.
  44. Talmadge, James E.; Rosenthal, Gary J.; Etter, Jeffrey B., Methods for use of delivery composition for expanding, activating, committing or mobilizing one or more pluripotent, self-renewing and committed stem cells.
  45. Peled, Tony; Fibach, Eitan; Treves, Avi, Methods of controlling proliferation and differentiation of stem and progenitor cells.
  46. Peled, Tony; Fibach, Eitan; Treves, Avi, Methods of controlling proliferation and differentiation of stem and progenitor cells.
  47. Peled,Tony; Fibach,Eitan; Treves,Avi, Methods of controlling proliferation and differentiation of stem and progenitor cells.
  48. Peled,Tony; Fibach,Eitan; Treves,Avi, Methods of controlling proliferation and differentiation of stem and progenitor cells.
  49. Peled, Tony; Steinhardt, Yair, Methods of culturing and expanding mesenchymal stem cells.
  50. Peled, Tony; Treves, Avi; Rosen, Oren, Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby.
  51. Peled,Tony; Treves,Avi; Rosen,Oren, Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby.
  52. Hariri, Robert J.; Heidaran, Mohammad A.; Jasko, Stephen; Kang, Lin; Law, Eric; Pal, Ajai; Stout, Bhavani; Voskinarian-Berse, Vanessa; Zeitlin, Andrew; Zhang, Xiaokui, Methods of generating natural killer cells.
  53. Hariri, Robert J.; Heidaran, Mohammad A.; Jasko, Stephen; Kang, Lin; Law, Eric; Pal, Ajai; Stout, Bhavani; Voskinarian-Berse, Vanessa; Zeitlin, Andrew; Zhang, Xiaokui, Methods of generating natural killer cells.
  54. Jamieson, Catriona Helen M.; Ailles, Laurie; Reya, Tannishtha; Weissman, Irving L., Methods of identifying and isolating stem cells and cancer stem cells.
  55. Jamieson,Catriona Helen M.; Ailles,Laurie Elizabeth; Reya,Tannishtha; Weissman,Irving L., Methods of identifying and isolating stem cells and cancer stem cells.
  56. Peled, Tony, Methods of improving stem cell homing and engraftment.
  57. Rubin, Jeffrey S.; Cumberledge, Susan; Reichsman, Frieda; Uren, Aykut, Methods of use of fragments of secreted frizzled related protein, sFRP.
  58. Hariri, Robert J.; Stirling, David I.; Moutouh-De Parseval, Laure A.; Chan, Kyle W. H., Modulation of stem and progenitor cell differentiation, assays, and uses thereof.
  59. Hariri,Robert J.; Stirling,David I.; Moutouh De Parseval,Laure A.; Chan,Kyle W. H., Modulation of stem and progenitor cell differentiation, assays, and uses thereof.
  60. Rasschaert, Kristien; Goddeeris, Bruno; Cox, Eric; Deforce, Dieter, Mucosal membrane receptor and uses thereof.
  61. Rasschaert, Kristien; Goddeeris, Bruno; Cox, Eric; Deforce, Dieter, Mucosal membrane receptor and uses thereof.
  62. Zhang, Xiaokui; Hariri, Robert J.; Voskinarian-Berse, Vanessa; Kang, Lin; Law, Eric; Abbot, Stewart, Natural killer cells from placenta.
  63. Filion,Mario C.; Phillips,Nigel C., Oligonucleotide compositions and their use to induce differentiation of cells.
  64. Edinger, James; Ye, Qian; Wang, Jai-Lun; Hariri, Robert J., Placental stem cell populations.
  65. Edinger, James; Ye, Qian; Wang, Jai-Lun; Hariri, Robert J., Placental stem cell populations.
  66. Edinger, James; Ye, Qian; Wang, Jai-Lun; Hariri, Robert J., Placental stem cell populations.
  67. Edinger, James; Ye, Qian; Wang, Jai-Lun; Hariri, Robert J., Placental stem cell populations.
  68. Hariri, Robert J., Placental stem cell populations.
  69. Hariri, Robert J., Placental stem cells.
  70. Hariri,Robert J., Placental stem cells.
  71. Hariri, Robert J., Placental stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells.
  72. Cicerone,Marcus T.; Tellington,Andrew; Trost,Landon; Sokolov,Alexei, Plasticized hydrophilic glasses for improved stabilization of biological agents.
  73. Hariri,Robert J., Post-partum mammalian placenta, its use and placental stem cells therefrom.
  74. Hariri, Robert J., Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells.
  75. Rubin,Jeffrey S.; ��ren,Aykut; Gillespie,Matthew Todd; Horwood,Nicole Joy, SFRP and peptide motifs that interact with SFRP and methods of their use.
  76. Reichsman,Frieda; ?ren,Aykut; Rubin,Jeffrey S.; Cumberledge,Susan, Secreted frizzled related protein fragments.
  77. Rubin, Jeffrey S.; Cumberledge, Susan; Reichsman, Frieda; Uren, Aykut, Secreted frizzled related protein, sFRP, fragments and methods of use thereof.
  78. Hariri, Robert J., Tissue matrices comprising placental stem cells.
  79. Hariri, Robert J.; Gurney, Jodi P., Treatment of amyotrophic lateral sclerosis using placental stem cells.
  80. Zhang, Xiaokui; Yaccoby, Shmuel; Abramson, Sascha; Hariri, Robert J., Treatment of bone-related cancers using placental stem cells.
  81. Hariri, Robert J., Treatment of diseases or disorders using placental stem cells.
  82. Edinger, James W.; Hariri, Robert J.; Wang, Jia-Lun; Ye, Qian; Faleck, Herbert, Treatment of inflammatory diseases using placental stem cells.
  83. Edinger, James W.; Hariri, Robert J.; Wang, Jia-Lun; Ye, Qian; Faleck, Herbert, Treatment of inflammatory diseases using placental stem cells.
  84. Paludan, Casper; Edinger, James W.; Harbacheuski, Ryhor; Murray, RoseAnn; Hariri, Robert J., Treatment of multiple sclerosis using placental stem cells.
  85. Hariri, Robert J., Treatment of organ injuries and burns using placental stem cells.
  86. Herzberg, Uri; Gurney, Jodi P., Treatment of pain using placental stem cells.
  87. Edinger, James W.; Hariri, Robert J.; Wang, Jia-Lun; Ye, Qian; Faleck, Herbert, Treatment of psoriasis using placental stem cells.
  88. Hariri, Robert J., Treatment of radiation injury using placental stem cells.
  89. Edinger, James W.; Fischkoff, Steven Alan; Francki, Aleksandar; Jankovic, Vladimir; Liang, Bitao; Martin, Philippe; Ray, Cynthia; Zhang, Xiaokui, Treatment of sarcoidosis using placental stem cells.
  90. Hariri, Robert J., Treatment of stroke using placental stem cells.
  91. Hariri, Robert J.; Heidaran, Mohammad A.; Kang, Lin; Padliya, Neerav Dilip; Pal, Ajai; Voskinarian-Berse, Vanessa; Zeitlin, Andrew; Zhang, Xiaokui, Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells.
  92. Hariri, Robert J.; Heidaran, Mohammad A.; Kang, Lin; Padliya, Neerav Dilip; Pal, Ajai; Voskinarian-Berse, Vanessa; Zeitlin, Andrew; Zhang, Xiaokui, Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells.
  93. Tannishtha Reya ; Roeland Nusse ; Irving L. Weissman, Use of .beta.-catenin in the expansion of stem and progenitor cells.
  94. Lee, Mark; Kuo, Calvin Jay; Reya, Tannishtha; Weissman, Irving L., Use of WNT inhibitors to augment therapeutic index of chemotherapy.
  95. Helms, Jill, Use of liposomal WNT composition to enhance osseointegration.
  96. Helms, Jill, Use of liposomal Wnt composition to enhance osseointegration.
  97. Chen, Tingchao; Zhao, Yi; Anderson, W. French, Uses of IL-12 in hematopoiesis.
  98. Chen, Tingchao; Zhao, Yi; Anderson, W. French, Uses of IL-12 in hematopoiesis.
  99. Chen, Tingchao; Zhao, Yi; Anderson, W. French, Uses of IL-12 in hematopoiesis.
  100. Matthews William ; Austin Timothy W., Uses of Wnt polypeptides.
  101. Rhee, Chae-Seo; Sen, Malini; Wu, Christina; Leoni, Lorenzo M.; Corr, Maripat; Carson, Dennis A., Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas.
  102. Rhee, Chae-Seo; Sen, Malini; Wu, Christina; Leoni, Lorenzo M.; Corr, Maripat; Carson, Dennis A., Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas.
  103. Rubin, Jeffrey S.; Üren, Aykut; Kay, Brian K.; Weisblum, Bernard; Gillespie, Matthew Todd; Horwood, Nicole Joy, sFRP and peptide motifs that interact with sFRP and methods of their use.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로