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특허 상세정보

Gas driven gene delivery instrument

국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61M-005/30   
미국특허분류(USC) 604/071 ; 604/024 ; 239/311
출원번호 US-0767374 (1996-12-16)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Robins & AssociatesMcCracken
인용정보 피인용 횟수 : 56  인용 특허 : 11
초록

A gas driven apparatus for accelerating particles coated with a genetic material into a target comprises a reservoir for releasably retaining a gas at a sufficiently high pressure to detach the particles from the surface of a sample cartridge and to carry the particles through the apparatus toward the target. When leaving the apparatus, the particles entrained in the gas stream pass through a substantially conical exit nozzle which causes the pattern of distribution of the particles to greatly expand. Methods for using the apparatus and for preparing the...

대표
청구항

[ I claim:] [1.] A gene delivery instrument comprising:a body having a particle acceleration passage formed therein, said acceleration passage having an opening at one end thereof,means for connecting the acceleration passage with a source of compressed gas to selectively admit gas into said passage, thereby forming an accelerating gas stream;a cartridge chamber adapted to accept and retain a particle cartridge containing carrier particles coated with a genetic material, said cartridge chamber arranged within the acceleration passage such that the accele...

이 특허에 인용된 특허 (11)

  1. McCabe Dennis E. (Middleton WI) Martinell Brian J. (Madison WI). Apparatus for genetic transformation. USP1992095149655.
  2. McCabe Dennis E. (Middleton WI) Martinell Brian J. (Madison WI) Glaser Donald A. (Berkeley CA). Apparatus for genetic transformation. USP1992065120657.
  3. Newman Jack (Queenscliff AUX) Monroe James A. (Turramurra AUX). Apparatus for hypodermic injection of liquids. USP1991045009637.
  4. Mann Derek (Derby GB2). Apparatus for the oral administration of capsules to animals. USP1987014637816.
  5. Sanford John C. (Geneva NY) Wolf Edward D. (Ithaca NY) Allen Nelson K. (Newfield NY). Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner. USP1993015179022.
  6. McCabe Dennis E. (Middleton WI). Gas driven gene delivery instrument. USP1996125584807.
  7. Sanford John C. (Geneva) DeVit Michael J. (Geneva NY) Bruner Ronald F. (Sewell NJ) Johnston Stephen A. (Durham NC). Method and apparatus for introducing biological substances into living cells. USP1993045204253.
  8. Sanford John C. (Geneva NY) Wolf Edward D. (Ithaca NY) Allen Nelson K. (Newfield NY). Method for transporting substances into living cells and tissues and apparatus therefor. USP1990074945050.
  9. Christou Paul (Madison WI) McCabe Dennis (Middleton WI) Swain William F. (Madison WI) Barton Kenneth A. (Middleton WI). Particle-mediated transformation of soybean plants and lines. USP1991055015580.
  10. Stewart R. Glen (Lake Villa IL). Pellet carrier fed pellet implanter apparatus. USP1992045106370.
  11. Burns Marvin (Marina Del Rey CA). Pre-filled ampule and non-invasive hypodermic injection device assembly. USP1990074941880.

이 특허를 인용한 특허 피인용횟수: 56

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  7. Silvester, Ivonne. Device for storing and administering active substances. USP2012018105291.
  8. Prausnitz, Mark R.; Allen, Mark G.; Henry, Sebastien; McAllister, Devin V.; Ackley, Donald E.; Jackson, Thomas. Devices and methods for enhanced microneedle penetration of biological barriers. USP2004066743211.
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  11. Uhland, Scott; Peeters, Eric. Drug delivery devices and methods with collimated gas stream and release-activatable tape. USP2013078486002.
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  15. McCalmon, Pat; Smolliarov, Boris; Mathews, Mike. Handpiece for jet injector. USP200404D488862.
  16. Erickson,Larry; Zhang,Jian. Harvest-inducible genes from alfalfa () and methods of use thereof. USP2008067388091.
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