|국가/구분||United States(US) Patent 등록|
|미국특허분류(USC)||604/071 ; 604/024 ; 239/311|
|발명자 / 주소|
|출원인 / 주소|
|대리인 / 주소||
|인용정보||피인용 횟수 : 56 인용 특허 : 11|
A gas driven apparatus for accelerating particles coated with a genetic material into a target comprises a reservoir for releasably retaining a gas at a sufficiently high pressure to detach the particles from the surface of a sample cartridge and to carry the particles through the apparatus toward the target. When leaving the apparatus, the particles entrained in the gas stream pass through a substantially conical exit nozzle which causes the pattern of distribution of the particles to greatly expand. Methods for using the apparatus and for preparing the...
[ I claim:] [1.] A gene delivery instrument comprising:a body having a particle acceleration passage formed therein, said acceleration passage having an opening at one end thereof,means for connecting the acceleration passage with a source of compressed gas to selectively admit gas into said passage, thereby forming an accelerating gas stream;a cartridge chamber adapted to accept and retain a particle cartridge containing carrier particles coated with a genetic material, said cartridge chamber arranged within the acceleration passage such that the accele...