초록 ▼

the adsorbent particles have a relative density with respect to the liquid which is less than 0.95 or greater than 1.1 and a particle size within the range of 50-750 .mu.m, and each of the relative density and particle size range of the adsorbent particles is selected to provide desired floatation/s

the adsorbent particles have a relative density with respect to the liquid which is less than 0.95 or greater than 1.1 and a particle size within the range of 50-750 .mu.m, and each of the relative density and particle size range of the adsorbent particles is selected to provide desired floatation/sedimentation properties of the adsorbent particles in the liquid in the fluidized bed process with substantially no turbulence.

대표청구항 ▼

[ We claim:] [1.] In a fluidized bed chromatographic process for purification and binding of molecules in a liquid by binding said molecules to an active substance covalently bound to chromatographic adsorbent particles in which process a fluidized bed of said adsorbent particles is formed and said

[ We claim:] [1.] In a fluidized bed chromatographic process for purification and binding of molecules in a liquid by binding said molecules to an active substance covalently bound to chromatographic adsorbent particles in which process a fluidized bed of said adsorbent particles is formed and said liquid is passed through the fluidized bed, the improvement wherein the chromatographic adsorbent particles comprise a porous composite material having pores allowing access to the interior of the composite material by said molecules, wherein the porous composite material of each absorbent particle, consists of:(i) a single density controlling particle which is either (a) a hollow low density particle which is impermeable to the liquid and has a density providing floatation of the adsorbent particle in said liquid or, (b) a high density particle having a density providing sedimentation of the adsorbent particle in said liquid;(ii) a matrix formed by consolidating at least one conglomerating agent selected from the group consisting of natural and synthetic organic monomers and polymers; and(iii) an active substance for binding molecules in said liquid;said density controlling particle being embedded in said matrix, and said active substance being covalently bound to said matrix; wherein;said adsorbent particles have a relative density with respect to said liquid which is less than 0.95 or greater than 1.1 and a particle size within the range of 1-1000 .mu.m, and each of the relative density and particle size range of said adsorbent particles is selected to provide desired floatation/sedimentation properties of said adsorbent particles in the liquid in said fluidized bed process with substantially no turbulence in the fluidized bed.