초록 ▼

The present invention is generally directed to methods, apparatus and systems for use in performing in situ dilution or concentration of a particular subject material in a microfluidic device or system. These methods and apparatus may generally be integrated with other microfluidic operations and/or

The present invention is generally directed to methods, apparatus and systems for use in performing in situ dilution or concentration of a particular subject material in a microfluidic device or system. These methods and apparatus may generally be integrated with other microfluidic operations and/or systems, to perfom a number of different manipulations, wherein dilution or concentration, carried out within the context of the microfluidic device or system, is just one part.

대표청구항 ▼

[ We claim:] [1.] A microfluidic system for diluting a material in a microfluidic device, the system comprising:a microfluidic device having at least a first main channel disposed therein, said main channel having at least one microscale cross-sectional dimension;at least a first source of said mate

[ We claim:] [1.] A microfluidic system for diluting a material in a microfluidic device, the system comprising:a microfluidic device having at least a first main channel disposed therein, said main channel having at least one microscale cross-sectional dimension;at least a first source of said material in fluid communication with said main channel at a first point alone a length of said main channel;at least a first diluent source in fluid communication with said main channel at a second point along said length of said main channel;at least a first reservoir in fluid communication with said main channel at a third point along said length of said main channel;at least a second diluent source in fluid communication with said main channel at a fourth point along said length of said main channel; anda fluid direction system for delivering diluent and material to said main channel from said first diluent source and said material source, respectively, combining said first diluent with said material to form first diluted material, transporting a first portion of said first diluted material out of said main channel into said first reservoir, a second portion of said first diluted material remaining in said main channel, and for second delivering diluent from said second diluent source into said main channel to mix with said second portion of first diluted material.