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Methods for nucleic acid analysis 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C12P-019/34
  • C07H-021/02
  • C07H-021/04
출원번호 US-0873034 (1997-06-11)
발명자 / 주소
  • Fodor Stephen P. A.
  • Solas Dennis W.
  • Dower William J.
대리인 / 주소
    Pillsbury Madison & Sutro LLP
인용정보 피인용 횟수 : 146  인용 특허 : 13

초록 ▼

The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and

대표청구항 ▼

[ What is claimed is:] [1.] A method of using a fluorescent label to detect hybridization with polynucleotide probes of known sequence, said method comprising:(a) attaching said label to a target polynucleotide,(b) contacting under hybridization conditions said labeled target polynucleotide sequence

이 특허에 인용된 특허 (13)

  1. Southern Edwin (Oxford GB2), Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays.
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  3. Dattagupta Nanibhushan (New Haven CT) Crothers Donald M. (Northford CT), Coupling of nucleic acids to solid support by photochemical methods.
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  4. Dattagupta, Nanibhushan; Crothers, Donald M., Coupling of nucleic acids to solid support by photochemical methods.
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  5. Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA), Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof.
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  6. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of determining an ordered sequence of subfragments of a nucleic acid fragment by hybridization of oligonucleotide.
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  7. Drmanac Radoje T. (Belgrade YUX) Crkvenjakov Radomir B. (Belgrade YUX), Method of sequencing by hybridization of oligonucleotide probes.
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  8. Drmanac Radoje T. (Zvecanska 46 Beograd 11000) Crkvenjakov Radomir B. (Bulevar JNA 118 Beograd YUX 11000), Method of sequencing of genomes by hybridization of oligonucleotide probes.
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  9. Macevicz Stephen C. (21890 Rucker Dr. Cupertino CA 95014), Nucleic acid sequence determination by multiple mixed oligonucleotide probes.
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  10. Dattagupta Nanibhushan (New Haven CT) Albarella James P. (Elkhart IN), Photochemical nucleic acid-labeling reagent having a polyalklamine spacer.
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  11. Mullis Kary B. (La Jolla CA) Erlich Henry A. (Oakland CA) Gelfand David H. (Oakland CA) Horn Glenn (Emeryville CA) Saiki Randall K. (Richmond CA), Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme.
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