초록 ▼

A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be app

A process and apparatus for one-step preparation of fibrinogen adhesive by polyethylene glycol-mediated precipitation from plasma are disclosed. The methods and apparatus of the invention permit preparation of autologous fibrinogen adhesive composition from the patient during surgery, and can be applied generally to provide such compositions. Also disclosed are an apparatus and method for application of sealant comprising this fibrinogen adhesive composition.

대표청구항 ▼

[ What is claimed is:] [1.] A supply device for dispensing a composition onto an animal subject to treat said subject, said device having a front end and a back end and comprisingat least one dispensing means having an inlet port and an outlet port, said inlet port in fluid communication with a rese

[ What is claimed is:] [1.] A supply device for dispensing a composition onto an animal subject to treat said subject, said device having a front end and a back end and comprisingat least one dispensing means having an inlet port and an outlet port, said inlet port in fluid communication with a reservoir configured to contain said composition or a component thereof;means for applying dispensing pressure to said reservoir only at discrete intervals so as to effect the flow of said composition or component to the inlet port through the dispensing means to the outlet port of said dispensing means; anddisposed adjacent to said outlet port a means to apply suction proximal to said outlet port; andmeans to control the amount of suction proximal to the outlet port.