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Targeted delivery via biodegradable polymers

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/16
  • A61K-038/18
  • A61K-038/19
출원번호 US-0787647 (1997-01-23)
발명자 / 주소
  • Roth Laurence A.
  • Herman Stephen Jack
출원인 / 주소
  • Focal, Inc.
대리인 / 주소
    Arnall Golden & Gregory, LLP
인용정보 피인용 횟수 : 458  인용 특허 : 1

초록

Delivery of bioactive molecules such as nucleic acid molecules encoding a protein can be significantly enhanced by immobilization of the bioactive molecule in a polymeric material adjacent to the cells where delivery is desired, where the bioactive molecule is encapsulated in a vehicle such as lipos

대표청구항

[ We claim:] [1.] A method for delivery of biologically active molecules to a targeted site in the vascular system of an animal where treatment is needed, the method comprisingselecting microparticles comprising a synthetic biodegradable polymer and biologically active molecules and having a diamete

이 특허에 인용된 특허 (1)

  1. Widder Kenneth J. (Carboro NC) Senyei Andrew E. (Long Beach CA), Method of delivering a therapeutic agent to a target capillary bed.

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