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특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Hemostyptic and tissue adhesive

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-038/00    C07K-014/00   
미국특허분류(USC) 514/012 ; 514/021 ; 530/381 ; 530/384
출원번호 US-0661070 (1996-06-10)
우선권정보 DE-0021324 (1995-06-12)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Foley & Lardner
인용정보 피인용 횟수 : 69  인용 특허 : 5
초록

A stable tissue adhesive is described which comprises fibrinogen and an activator or pro-activator of prothrombin, wherein its content of prothrombin present in blood is less than 5 units/g fibrinogen. This tissue adhesive can be present as a liquid or dry preparation and can optionally be applied to a biologically degradable water-soluble support.

대표
청구항

[ We claim:] [1.] A tissue adhesive, comprising a coagulation-effective amount of fibrinogen and a blood-derived activator or pro-activator of prothrombin, wherein said activator or pro-activator does not react with fibrinogen and wherein the tissue adhesive comprises less than 5 units prothrombin/g fibrinogen and is stable, wherein said adhesive clots only upon contact with tissue.

이 특허에 인용된 특허 (5)

  1. Zimmerman Eberhard (Munster DEX) Schiele Ulrich (Munich DEX). Composition for sealing and healing wounds. USP1984064453939.
  2. Yin E. Thye (2335 S. Hanley Rd. St. Louis MO 63144). Composition, kit and method for assaying heparin and a method for making the composition. USP1990084948724.
  3. Stroetmann Michael (Mnster DEX). Enriched plasma derivative for advancement of wound closure and healing. USP1984014427650.
  4. Stroetmann Michael (Mnster DEX). Fibrinogen-containing dry preparation, manufacture and use thereof. USP1984044442655.
  5. Heimburger Norbert (Marburg DEX) Fuhge Peter (Lahntal DEX) Ronneberger Hansjrg (Marburg DEX). One-component tissue adhesive and a process for the production thereof. USP1995045407671.

이 특허를 인용한 특허 피인용횟수: 69

  1. Ericson, Daniel Grant; Brandy, Kyle Robert. Adhesive compositions and related methods. USP2017019540548.
  2. Ericson, Daniel Grant; Brandy, Kyle Robert. Adhesive compositions and related methods. USP2017129833538.
  3. Suh, Hwal. Adhesive hemostatic agent based on porcine atelocollagen and method for production thereof. USP2014088809274.
  4. Suh, Hwal. Adhesive hemostatic agent based on porcine atelocollagen and method for production thereof. USP2011118067374.
  5. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108545857.
  6. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108563012.
  7. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108551506.
  8. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013128603494.
  9. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2013128603495.
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