초록 ▼

In a needle-less injector combining an actuator and a medicament cartridge, the actuator includes a housing with a forward portion to which the cartridge is connected. An impact member is mounted within the housing inward of the forward portion so as to be movable toward the forward portion, where i

In a needle-less injector combining an actuator and a medicament cartridge, the actuator includes a housing with a forward portion to which the cartridge is connected. An impact member is mounted within the housing inward of the forward portion so as to be movable toward the forward portion, where it may strike components of the cartridge to effect expulsion of a dose of medicament. A chamber is provided within the housing and is pre-filled with a pressurized gas which is in communication with and exerts a constant force on the impact member, tending to urge it towards the forward portion. Movement of the impact member is prevented by a latch which normally engages the impact member and prevents its forward movement, but is actuable to be moved out of such engagement, permitting movement of the impact member, the cartridge includes a piston which is mounted in the body of the cartridge with an interference fit and is made of a material which is substantially non-resilient when subjected to a slowly applied force, but is highly resilient when subjected to a rapidly applied force.

대표청구항 ▼

[ What is claimed is:] [1.] An actuator for use in conjunction with a cartridge to form a needle-less injector, the cartridge being prefilled with a liquid to be injected in a subject, the cartridge having a liquid outlet and a free piston inward of the liquid outlet in contact with the liquid, said

[ What is claimed is:] [1.] An actuator for use in conjunction with a cartridge to form a needle-less injector, the cartridge being prefilled with a liquid to be injected in a subject, the cartridge having a liquid outlet and a free piston inward of the liquid outlet in contact with the liquid, said actuator comprising:(a) a housing having a forward portion adapted to be connected with the cartridge;(b) impact member mounted within said housing inward of the forward portion so as to be movable from a first position toward the forward portion to strike the free piston when a cartridge is connected and to continue to move the free piston toward the liquid outlet whereby a dose of the liquid is expelled through the liquid outlet in the cartridge;(c) a chamber within said housing prefilled with pressurized gas and connected with said impact member such that said pressurized gas is constantly in communication with and constantly exerts a force on said impact member to normally urge said impact member toward the liquid outlet; and(d) a latch within said housing which engages said impact member to prevent movement of the impact member toward the forward portion in response to said force exerted by said pressurized gas, and being mounted to be movable out of engagement with said impact member to a firing position, in which said latch permits such movement.