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Enhancement of vascular function by modulation of endogenous nitric oxide production or activity 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A23L-013/05
  • A61K-009/00
  • A61K-031/195
출원번호 US-0556035 (1995-11-09)
발명자 / 주소
  • Cooke John P.
  • Dzau Victor J.
  • Gibbons Gary H.
출원인 / 주소
  • The Board of Trustees of the Leland Stanford Junior University
대리인 / 주소
    Rowland
인용정보 피인용 횟수 : 115  인용 특허 : 21

초록

Vascular function and structure is maintained or improved by long term administration of physiologically acceptable compounds, namely L-arginine, L-lysine, physiologically acceptable salts thereof, and polypeptide precursors thereof, which enhance the level of endogenous nitric oxide or other interm

대표청구항

[ What is claimed is:] [1.] A method of improving vascular NO activity of the vascular system of a human host by enhancing endothelial NO, said method comprising:administering orally as a dietary supplement to said host in accordance with a predetermined regimen a prophylactic dose in an amount suff

이 특허에 인용된 특허 (21)

  1. Adibi Siamak A. (Pittsburgh PA) Brandl Maria (Schwabach DEX) Fekl Werner (Rottenbach DEX) Langer Klaus (Erlangen DEX), Aqueous nutrient compositions comprising oligopeptides.
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  11. Zaloga Gary P. (Winston-Salem NC) Roberts Pamela (Winston-Salem NC), Method for treating acute renal disease and failure.
  12. Adibi Siamak A. (1154 Wightman St. Pittsburgh PA 15217), Nutrient compositions and method of administering the same.
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  17. Rath Matthias (Woodside CA) Pauling Linus (Big Sur CA), Therapeutic lysine salt composition and method of use.
  18. Cooke John P. (Palo Alto CA) Dzau Victor J. (Los Altos Hills CA) Gibbons Gary H. (Palo Alto CA), Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production of activity.
  19. Levere Richard D. (5 Seymour Pl. W. Armonk NY 10504) Abraham Nader G. (143 Charter Cir. Ossining NY 10562) Schwartzman Michel L. (415 Old Country Rd. Elmsford NY 10523) Martasek Pavel (60 Hillcrest R, Use of L-arginine in the treatment of hypertension and other vascular disorders.
  20. Yoshimura Norman N. (Westminster CA) Barbul Adrian (Baltimore MD) Tao Robert C. (Huntington Beach CA) Storm Michael C. (Laguna Niguel CA) Kelley Robert E. (Orange CA) Reis Brenda L. (Costa Mesa CA), Use of arginine as an immunostimulator.
  21. Meade Thomas L. (187 Walmsley La. Saunderstown RI 02874), Water-insoluble amino acid salt.

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