초록 ▼

The present invention provides a capsule made of a biologically compatible material with sufficient mechanical strength to form a very thin membrane shell having at least a region with approximately uniformly sized and spaced holes or pores that are large enough to let a desired biologically active

The present invention provides a capsule made of a biologically compatible material with sufficient mechanical strength to form a very thin membrane shell having at least a region with approximately uniformly sized and spaced holes or pores that are large enough to let a desired biologically active molecular product through, while blocking the passage of all larger immunological molecules. The present invention thus provides an immunological isolation of cell transplants contained therein. The present invention also provides a free standing thin film structure that may be used as a component of such a capsule and method for the fabrication of such component and capsules.

대표청구항 ▼

[ What is claimed is:] [8.] A microfabricated containment capsule, comprising:a shell formed of a thin film inorganic material, said shell including high vertical aspect thin film side walls and rib members to provide additional structural support for said side walls;a first porous area microfabrica

[ What is claimed is:] [8.] A microfabricated containment capsule, comprising:a shell formed of a thin film inorganic material, said shell including high vertical aspect thin film side walls and rib members to provide additional structural support for said side walls;a first porous area microfabricated at one end of the shell, and a second porous area microfabricated at another end of the shell, the first and second porous areas having opposing faces with an array of pores of predetermined, approximately uniform size and distribution for filtering particles across the opposing faces; andsaid shell providing a selective molecular barrier between the interior and the exterior of said capsule.