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Topical delivery of L-arginine to cause tissue warming

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-006/00
  • A61K-007/00
출원번호 US-0936188 (1997-09-17)
발명자 / 주소
  • Fossel Eric T.
대리인 / 주소
    Lorusso & Loud
인용정보 피인용 횟수 : 43  인용 특허 : 2

초록

A preparation is disclosed for producing enhanced blood flow in tissue thus causing beneficial effects such as warming cold tissue of the hands and feet. Specifically, this is a preparation which provides local delivery of the amino acid L-arginine, an important biological precursor to the main subs

대표청구항

[ What is claimed is:] [1.] A method of warming tissue comprising delivering a nitric oxide releasing substance selected from a member of the group consisting of L-arginine, L-arginine salts and L-arginine derivatives, to skin comprising the step of topically applying to the skin a vehicle containin

이 특허에 인용된 특허 (2)

  1. Brand Larry M. (West Chester OH), Pharmaceutical products providing enhanced analgesia.
  2. Hechtman Herbert B. (Chestnut Hill MA), Topical formulations and methods for treating hemorrhoidal pain and sphincter and smooth muscle spasm in the gastrointes.

이 특허를 인용한 특허 (43)

  1. Kintz, Gregory J.; McMillan, William A.; Wisniewski, Natalie A., Apparatus and methods for detecting optical signals from implanted sensors.
  2. Ohta, Fumio; Takagi, Tomo; Sato, Hiroyuki, Arginine-containing compositions and methods for increasing blood flow using same.
  3. Whitlock, David R., Articles of clothing treated with ammonia oxidizing bacteria to produce nitric oxide.
  4. Fossel, Eric T., Beneficial effects of increasing local blood flow.
  5. Whitlock, David R., Compositions including ammonia oxidizing bacteria to increase production of nitric oxide and nitric oxide precursors and methods of using same.
  6. Stephens, Laura; Masiz, John J.; Carter, Stephen G.; Zhu, Zhen; Patel, Kanu, Control of blood vessel physiology to treat skin disorders.
  7. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  8. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  9. Fossel, Eric T., Delivery of ibuprofen and other compounds.
  10. Thompson, Ronald J., Expanded clitoral sensitizing compounds with methods and apparatus for the delivery of these compounds.
  11. Sakai, Yasushi; Kato, Aki; Kimura, Masao, Glutathione preparation and method for production thereof.
  12. Carter, Stephen G.; Zhu, Zhen; Patel, Kanu; Kozwich, Diane, Ibuprofen for topical administration.
  13. Kintz, Gregory J.; McMillan, William; Wisniewski, Natalie, Method and device for correcting optical signals.
  14. McMillan, William A.; Wisniewski, Natalie, Method and system for directing a localized biological response to an implant.
  15. Carter, Stephen G.; Zhu, Zhen; Patel, Kanu; Kozwich, Diane L.; Stephens, Laura; Masiz, John J.; Donabedian, David H., Methods and compositions for tattoo removal.
  16. LaTonya Kilpatrick-Liverman ; Zeenat Nabi ; Thomas G. Polefka ; Elizabeth D. Volz ; Melonie D. Brown, Skin moisturizing composition comprising a choline salt.
  17. Kilpatrick-Liverman LaTonya ; Nabi Zeenat ; Polefka Thomas G., Solid cleansing composition comprising a choline salt.
  18. Ahmad, Nawaz; Cui, Cheng-Ji; Eknoian, Michael; Walters, Russel; Librizzi, Joseph James; Moscherosch, H. Michael; Ison, Bryant; Mohary, Stephen J., Substantially anhydrous sprayable personal lubricant.
  19. Fossel, Eric T., Systems and methods for treatment of allergies and other indications.
  20. Short, Dan C.; Ouimet, Albert B.; Short, Bryan S., Thermocromatic patch for monitoring/detecting body temperature.
  21. Wisniewski, Natalie A.; Petersen, Kurt E.; Helton, Kristen; McMillan, William A., Tissue-integrating electronic apparatus.
  22. Wisniewski, Natalie A.; Helton, Kristen; McMillan, William A., Tissue-integrating sensors.
  23. Fossel, Eric T., Topical composition containing ibuprofen.
  24. Fossel, Eric T., Topical composition containing naproxen.
  25. Barone, Jr.,Frank V.; Jacobsen,Christopher; Chumenko,Kirill, Topical compositions for enhancing sexual responsiveness.
  26. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
  27. Fossel, Eric T., Topical delivery of L-arginine to cause beneficial effects.
  28. Fossel, Eric Thor, Transdermal delivery of beneficial substances effected by a hostile biophysical environment.
  29. Carter, Stephen G.; Zhu, Zhen; Patel, Kanu; Masiz, John J., Transdermal drug delivery using an osmolyte and vasoactive agent.
  30. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  31. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  32. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  33. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  34. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  35. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  36. Fossel, Eric T., Treatment of erectile dysfunction and other indications.
  37. Thompson, Ronald J., Treatment of interstitial cystitis using topical application of menthol and L-arginine.
  38. Ahmad, Nawaz; Lamb, C. Scott; Lonardo, Emilia Casilio; Joyce, Michael E.; Patel, Kalpana J.; Heda, Pavan Kumar, Warming and nonirritating lubricant compositions and method of comparing irritation.
  39. Ahmad, Nawaz; Lamb, Christopher Scott; Lonardo, Emilia Casilio; Joyce, Michael E.; Patel, Kalpana J.; Heda, Pavan Kumar, Warming and nonirritating lubricant compositions and method of comparing irritation.
  40. Ahmad, Nawaz; Lamb, Christopher Scott; Lonardo, Emilia Casilio; Joyce, Michael E.; Patel, Kalpana J.; Heda, Pavan Kumar, Warming and nonirritating lubricant compositions and method of comparing irritation.
  41. Ahmad,Nawaz; Lamb,C. Scott; Lonardo,Emilia Casilio, Warming and nonirritating lubricant compositions and method of comparing irritation.
  42. Ahmad,Nawaz; Sun,Ying; Lin,Shun Y., Warming and nonirritating lubricant compositions and method of comparing irritation.
  43. Ahmad,Nawaz; Sun,Ying; Lin,Shun Y., Warming and nonirritating lubricant compositions and method of comparing irritation.
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