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Materials and methods for the immobilization of bioactive species onto polymeric substrates 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B32B-027/00
  • B32B-017/06
  • G01N-033/53
  • C12N-011/08
출원번호 US-0138197 (1998-08-21)
발명자 / 주소
  • Drumheller Paul D.
출원인 / 주소
  • Gore Hybrid Technologies, Inc.
대리인 / 주소
    Sheets
인용정보 피인용 횟수 : 228  인용 특허 : 31

초록 ▼

The present invention is directed to support members having surfaces that are rendered hydrophilic for use as a substrate for the immobilization of bioactive species thereon. The hydrophilic surfaces are chemically stable on the support member. The surfaces are also chemically variable to provide a

대표청구항 ▼

[ What is claimed is:] [1.] A material having bioactive species immobilized thereto, said material comprising:a support member;a first layer comprised of at least one species of a polymeric surfactant non-covalently attached to the support member, wherein the polymeric surfactant is a different chem

이 특허에 인용된 특허 (31)

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  9. Branca Phillip A. (132 Country Flower Rd. Newark DE 19711) Hubis Daniel E. (227 Fair Hill Dr. Elkton MD 21921) Mallouk Robert S. (Box 332 ; R.D. #1 Chadds Ford PA 19317) Perry Randal L. (1006 Timberw, Electrolytic cell with composite, porous diaphragm.
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  10. Eveleigh John William d. (Hockessin DE) Kobos Robert K. (Wilmington DE), Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports.
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  11. Hato Masakatsu (Ibaraki JPX) Shimura Yukio (Ibaraki JPX) Tsuda Keishiro (Ibaraki JPX), Enzyme immobilization in a fluorine resin membrane.
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  12. Schmidt Donald L. (Midland MI) Coburn Charles E. (Midland MI) McCrackin Perry J. (Midland MI), Fluorocarbon containing, reactive polymeric surfactants and coating compositions therefrom.
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  13. Schmidt Donald L. (Midland MI) McCrackin Perry J. (Midland MI) Coburn Charles E. (Midland MI), Fluorocarbon containing, reactive polymeric surfactants and coating compositions therefrom.
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  14. Keogh James R. (Maplewood MN) Hobot Christopher M. (Tonka Bay MN) Eaton John W. (Troy NY) Jevne Allan H. (Anoka MN) Bergan Matthew A. (Brooklyn Park MN), Graft polymer articles having bioactive surfaces.
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  15. Abayasekara Dilip R. (Newark DE), Hydrophilic compositions with increased thermal and solvent resistance.
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  16. Abayasekara Dilip R. (Newark DE) Henn Robert L. (Wilmington DE), Hydrophilic compositions with increased thermal resistance.
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  17. Abayasekara Dilip R. (Newark DE) Henn Robert L. (Wilmington DE), Hydrophilic membranes.
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  18. Koyama Noriyuki (Fuji) Yokomati Shinsuke (Fujinomiya) Nemoto Yasushi (Fuji) Ohnishi Makoto (Fuji JPX), Hydrophilic porous membrane, method of manufacturing the same and liquid filter using the same.
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  19. Okita ; Koichi, Hydrophilic porous structures and process for production thereof.
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  20. Lowe Christopher Robin,GBX ; Parris Norman A ; Pitfield Ian,GBX ; Purvis Duncan Ross,GBX, Hydrophlic polymer coated perflurocarbon polymer matrices for bioaffinity separations.
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  21. Van Antwerp William P. (Westchester CA), Indwelling catheter with stable enzyme coating.
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  22. Graiver Daniel (Midland MI) Okada Toshiyuki (Midland MI) Serrano Samir D. (Midland MI), Method for grafting preformed hydrophillic polymers onto hydrophobic polymer substrates.
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  23. Matsuda Takehisa (Minoo JPX) Inoue Kazuhiko (Kobe JPX) Tani Nobutaka (Osaka JPX), Method for manufacturing medical device having a highly biocompatible surface.
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  24. Yamada Katsuya (Osaka JPX) Okita Koichi (Osaka JPX) Toyo-oka Shin-ichi (Osaka JPX) Asako Shigeru (Osaka JPX), Method for treating the surface of a thin porous film material of tetrafluoroethylene resin.
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  25. Koontz Steven L. (Seabrook TX) Spaulding Glenn F. (Houston TX), Method of making a membrane having hydrophilic and hydrophobic surfaces for adhering cells or antibodies by using atomic.
    상세보기
  26. McAuslan Brian R. (Clareville AUX) Steele John G. (North Rocks AUX) Norris William (North Sydney AUX) Johnson Graham (Peakhurst AUX), Neutralized perfluoro-3,6-dioxa-4-methyl-7-octene sulphonyl fluoride copolymer surface for attachment and growth of anim.
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  27. Matsuda Takehisa (Minoo JPX) Sugawara Takashi (Ikeda JPX) Inoue Kazuhiko (Kobe JPX) Tani Nobutaka (Osaka JPX), Process for modifying surfaces of materials.
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  28. Larm Karl O. P. (Bromma SEX) Adolfsson Lars A. (Uppsala SEX) Olsson Kjell P. (Uppsala SEX), Process for the preparation of surface modified solid substrates.
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  29. Larm Karl O. P. (Bromma SEX) Adolfsson Lars A. (Uppsala SEX) Olsson Kjell P. (Uppsala SEX), Process for the preparation of surface modified solid substrates.
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  30. Zukowski Stanislaw L. (Flagstaff AZ), Surface modified porous expanded polytetrafluoroethylene and process for making.
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  31. Hubbell Jeffrey A. (Austin TX) Massia Stephen P. (Austin TX) Desai Neil P. (Austin TX), Surfaces having desirable cell adhesive effects.
    상세보기

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