[특허]Device structure for iontophoresis

Device structure for iontophoresis 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61N-001/30
출원번호	US-0878852 (1997-06-20)
우선권정보	JP-0181481 (1996-06-20)
발명자 / 주소	Higo Naruhito,JPX Adachi Hirotoshi,JPX Meno Tatsuya,JPX
출원인 / 주소	Hisamitsu Pharmaceutical Co., Inc., JPX
대리인 / 주소	Flynn, Thiel, Boutell & Tanis, P.C.
인용정보	피인용 횟수 : 14 인용 특허 : 24

초록 ▼

An iontophoretic device structure of the dissolution-on-use type is provided, wherein an ionized drug is transdermally or transmucosally administered into a living body. The device structure comprises (a) a non-polarizable electrode, (b) a hydrophilic, polymeric gel layer containing an ion exchange resin which is able to specifically inhibit the movement of ions dissolved out from the electrode while in use, and (c) a drug layer containing a drug in a dry condition in a drug retaining membrane, wherein when said device is in use, said drug layer is brought into contact with said hydrophilic, polymeric gel layer so that said drug in the dry condition is dissolved. A humectant may be contained in the hydrophilic, polymeric gel layer and/or the drug layer.

대표청구항 ▼

[ What is claimed is:] [1.] An iontophoretic device structure of the dissolution-on-use type wherein an ionized drug is transdermally or transmucosally administered into a living body, the device structure comprising (a) a non-polarizable electrode, (b) a hydrophilic, polymeric gel layer having an ion exchange resin dispersed therein which is capable of specifically inhibiting the movement of ions dissolved out from the electrode, and (c) a drug layer containing a drug in a dry condition in a drug retaining membrane, wherein, said drug layer is adapted to be brought into contact with said hydrophilic, polymeric gel layer during use of said device so that said drug in the dry condition is dissolved.

이 특허에 인용된 특허 (24)

Sarantakis Dimitrios (West Chester PA), Anti-ovulatory decapeptides.
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Gyory J. Richard (San Jose CA) Haak Ronald P. (San Jose CA) Theeuwes Felix (Los Altos CA), Control membrane for electrotransport drug delivery.
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Chien Yie W. (North Brunswick NJ) Chen Li-Lan H. (Edison NJ), Disposable dosage unit for iontophoresis-facilitated transdermal delivery, related devices and processes.
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Haak Ronald P. (Menlo Park CA), Electrotransport device having improved cathodic electrode assembly.
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Gyory J. Richard (Los Altos CA) Haak Ronald P. (Cupertino CA) Theeuwes Felix (Los Altos CA), Electrotransport transdermal system.
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Haak Ronald P. (Cupertino CA) Theeuwes Felix (Los Altos CA) Gyory J. Richard (Los Altos CA), Electrotransport transdermal system.
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Ariura Shunsuke (Matsudo JPX) Ogata Tadashi (Fuchu JPX) Kashima Norie (Tokyo JPX) Morihata Michiyo (Fuchu JPX), Iontophoresis device.
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Sasaki Minoru (Yokohama JPX), Iontophoresis device.
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Atanasoska Ljiljana, Iontophoresis electrode.
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Haak Ronald P. (San Jose CA) Gyory J. Richard (San Jose CA) Theeuwes Felix (Los Altos CA) Landrau Felix A. (San Jose CA) Roth Nathan (San Francisco CA) Myers Robert M. (Stanford CA), Iontophoretic delivery device and method of hydrating same.
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Chien Yie W. (North Brunswick NJ) Banga Ajay K. (Rochester NY), Iontotherapeutic devices, reservoir electrode devices therefore, process and unit dose.
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Coy David H. (4319 Perrier St. New Orleans LA 70115) Schally Andrew V. (5025 Kawanee Ave. Metairie LA 70002), LH-RH Antagonists.
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Theeuwes Felix (Los Altos CA) Gyory J. Richard (Los Altos CA) Haak Ronald P. (Cupertino CA), Membrane for electrotransport transdermal drug delivery.
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Fujino Masahiko (Takarazuka JA) Fukuda Tsunehiko (Osaka JA) Shinagawa Susumu (Osaka JA), Nonapeptide amide analogs of luteinizing releasing hormone.
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Fujino Masahiko (Takarazuka JPX) Nishimura Osamu (Toyonaka JPX) Takaoki Muneo (Kyoto JPX), Nonapeptides.
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Tinney ; Francis J. ; Lunney ; Elizabeth A. ; Nicolaides ; Ernest D., Nonapeptides and methods for their production.
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Wittle ; Eugene Leroy ; Rebstock ; Mildred Catherine, Nonapeptides and methods for their production.
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Fujino Masahiko (Takarazuka JA) Shinagawa Susumu (Osaka JA) Fukuda Tsunehiko (Suita JA), Novel decapeptide amide analogs of leuteinizing hormone-releasing hormone.
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Sarantakis Dimitrios (West Chester PA), Peptides related to somatostatin.
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Shields ; James E., Somatostatin analogs and intermediates thereto.
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Shields ; James E., Somatostatin analogs and intermediates thereto.
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Shields ; James E., Somatostatin analogs and intermediates thereto.
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Fujino Masahiko (Hyogo JPX) Shinagawa Susumu (Osaka JPX) Kawai Kiyohisa (Kyoto JPX), Tetrapeptidehydrazide derivatives.
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Bannon Yvonne B. (County Kildare IEX) Corish John (County Dublin IEX) Corrigan Owen I. (County Dublin IEX) Masterson Joseph G. (Dublin IEX), Transdermal drug delivery device.
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이 특허를 인용한 특허 (14)

Yanaki, Jamal S., Active electrode for transdermal medicament administration.
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Yanaki, Jamal S., Active transdermal medicament patch and circuit board for same.
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Thomas O. Murdock, Anhydrous drug reservoir for electrolytic transdermal delivery device.
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Domb, Abraham J., Device, methods and sponges for iontophoretic drug delivery.
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Keusch, Preston; Jain, Uday K.; Reddy, Vilambi Nrk; Eliash, Bruce M.; Carey, Kevin John; Falevich, Vitaly, Electrodes and method for manufacturing electrodes for electrically assisted drug delivery.
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Adachi, Hirotoshi; Katagai, Kazuya; Higo, Naruhito, Iontophoresis device.
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Matsumura,Akihiko; Torisawa,Sakae; Kanamura,Kiyoshi; Ito,Yoshihiro; Kobayashi,Yoriko, Iontophoresis device.
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Iga, Katsumi; Suzuki, Yasuyuki; Kawase, Masahiro, Iontophoresis method.
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Durand, Emma Amelia; Becker, Bruce Mark, Iontophoretic device for application to the brow/forehead of a person.
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Degim,Tuncer; Ilbasmis,Sibel; Degim,Zelihagul; Dundaroz,Rusen; Denli,Metin, Method for measuring blood urea level by reverse iontophoresis.
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Kraft, Edward R.; Kulp, Gabriela, Photokinetic delivery of biologically active substances using pulsed incoherent light.
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Kraft,Edward R.; Kulp,Gabriela, Photokinetic delivery of biologically active substances using pulsed incoherent light.
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Iwamoto, Yasukazu; Kitaoka, Naomi, Reference electrode with non-blocking liquid junction.
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Jain, Uday K.; Reddy, Vilambi N R K; Eliash, Bruce M.; Carey, Kevin John; Falevich, Vitaly; Keusch, Preston, Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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Device structure for iontophoresis 원문보기