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Inhibition of fibrosis by photodynamic therapy

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61B-017/00
출원번호 US-0741816 (1996-10-31)
발명자 / 주소
  • Trauner Kenneth
  • Hasan Tayyaba
  • Hamblin Michael R.
출원인 / 주소
  • The General Hospital Corporation
대리인 / 주소
    Fish & Richardson P.C.
인용정보 피인용 횟수 : 117  인용 특허 : 2

초록

Disclosed is a method for modulating wound healing in a mammal. The method includes the steps of: (a) administering a photosensitizer to a mammal that has an unhealed or partially-healed wound; (b) waiting for the photosensitizer to reach an effective tissue concentration at the wound site; (c) phot

대표청구항

[ We claim:] [1.] A method for inhibiting fibrosis in the healing of a wound in a mammal, comprising:(a) administering to a mammal that has an unhealed or partially-healed wound an effective amount of a photosensitizer targeted to macrophages or myofibroblasts by conjugation of a targeting moiety;(b

이 특허에 인용된 특허 (2)

  1. Selman Steven H. (Toledo OH) Kropp Kenneth A. (Toledo OH) Haselhuhn Gregory D. (Toledo OH), Photochemical ablation of gastro-intestinal tissue for augmentation of an organ.
  2. Trauner Kenneth (Sacramento CA) Hasan Tayyaba (Arlington MA), Photodynamic therapy for the destruction of the synovium in the treatment of rheumatoid arthritis and the inflammatory a.

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