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Multiarmed, monofunctional, polymer for coupling to molecules and surfaces

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12N-009/96
  • C12N-011/06
  • C07K-017/00
  • A01N-063/00
출원번호 US-0443383 (1995-05-17)
발명자 / 주소
  • Harris J. Milton
  • Veronese Francesco Maria,ITX
  • Caliceti Paolo,ITX
  • Schiavon Oddone,ITX
출원인 / 주소
  • Shearwater Polymers, Inc.
대리인 / 주소
    Bell Seltzer Intellectual Property Law Group of Alston & Bird LLP
인용정보 피인용 횟수 : 573  인용 특허 : 5

초록

Multi-armed, monofunctional, and hydrolytically stable polymers are described having the structure [ STR 1 ] wherein Z is a moiety that can be activated for attachment to biologically active molecules such as proteins and wherein P and Q represent linkage fragments that join polymer arms poly.sub.a

대표청구항

[ What is claimed is:] [1.] An essentially pure water soluble polymer having a moiety located along the polymer backbone, which moiety comprises a single ionizable reactive group, wherein said polymer is represented by the structure: [ STR 30 ] wherein C is carbon; wherein R is a nonreactive moiety;

이 특허에 인용된 특허 (5)

  1. Guire Patrick E. (Eden Prairie MN), Binding reagents and methods.
  2. Ekwuribe Nnochiri N. (Southfield MI), Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and m.
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  5. Oh Chan S. (Diamond Bar CA) Sternberg James C. (Fullerton CA), Trifunctional conjugates.

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