$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Localized intravascular delivery of growth factors for promotion of angiogenesis 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61M-031/00
출원번호 US-0753224 (1996-11-22)
발명자 / 주소
  • Kaplan Aaron V.
  • Simons Michael
출원인 / 주소
  • Beth Israel Deaconess Medical Center
대리인 / 주소
    Townsend and Townsend and Crew LLP
인용정보 피인용 횟수 : 145  인용 특허 : 6

초록

Angiogenesis in cardiac and other tissues is promoted by the transmural delivery of angiogenic factors such as VEGF, FGF, EGF, and PDGF, through blood vessels and other body lumens into the surrounding tissue. Usually, the angiogenic factor is delivered using a catheter having infusion parts at its

대표청구항

[ What is claimed is:] [1.] A method for promoting angiogenesis in tissue surrounding a body lumen, said method comprising transmurally delivering an angiogenic factor at a target site within the body lumen.

이 특허에 인용된 특허 (6)

  1. Woods W. T. (R.R. 1-Box 13 Chatham IL 62629), Apparatus and method for angioplasty and for preventing re-stenosis.
  2. Shaffer Maureen A. (Miami FL) Leone James E. (Miami FL), Balloon catheter for delivering therapeutic agents.
  3. Sharkawy Ahmed (College Station TX), Catheter for even distribution of therapeutic fluids.
  4. March Keith L. (Carmel IN) Hathaway David R. (Indianapolis IN) Wilensky Robert L. (Indianapolis IN), Method for delivery of smooth muscle cell inhibitors.
  5. Unger Ellis F. (Silver Spring MD) Epstein Stephen E. (Rockville MD), Method to foster myocardial blood vessel growth and improve blood flow to the heart.
  6. Isner Jeffrey M. (Weston MA), Methods and products for nucleic acid delivery.

이 특허를 인용한 특허 (145)

  1. Mandrusov, Evgenia; Simhambhatla, Murthy V.; Hossainy, Syed; Michal, Eugene T.; Claude, Charles; Chiu, Jessica G., Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery.
  2. Gentsler,Curtis C., Alternate site gene therapy.
  3. Whitehouse, Martha J.; Kavanaugh, W. Michael, Angiogenically effective unit dose of FGF and method of administering.
  4. Mueller, Richard, Apparatus and method for delivering therapeutic and diagnostic agents.
  5. Mueller,Richard, Apparatus and method for delivering therapeutic and diagnostic agents.
  6. Saadat, Vahid; Ream, John H., Apparatus and methods for stimulating revascularization and/or tissue growth.
  7. Tartaglia, Joseph M.; Saadat, Vahid; Leopold, Eric W.; Park, Peter K.; Philip, Susan, Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and method of use.
  8. Ortega, Daniel Felipe; Giniger, Alberto German, Apparatus for treating the physiological electric conduction of the heart.
  9. Ortega, Daniel Felipe; Giniger, Alberto German, Apparatus for treating the physiological electric conduction of the heart.
  10. Saadat, Vahid; Ream, John H., Apparatus having stabilization members for percutaneously performing surgery and methods of use.
  11. Strauss, Bradley H.; Segev, Amit, Augmentation of intraluminal microvessel formation to facilitate guide wire crossing in chronic total occlusions.
  12. Genstler, Curtis; Hansmann, Douglas R., Catheter system.
  13. Soltani, Azita; Wilcox, Robert L., Catheter with multiple ultrasound radiating members.
  14. Wilson, Richard R.; Wilcox, Robert L.; Genstler, Curtis; Abrahamson, Tim; Barrere, Wm. Gerrit; Cohen, Amy; Keilman, George; Oliver, Leonard R.; Peskin, Natalya, Catheter with multiple ultrasound radiating members.
  15. Wilson, Richard R.; Wilcox, Robert L.; Genstler, Curtis; Abrahamson, Tim; Barrere, Wm. Gerrit; Cohen, Amy; Keilman, George; Oliver, Leonard R.; Peskin, Natalya, Catheter with multiple ultrasound radiating members.
  16. Wilson, Richard R.; Wilcox, Robert L.; Genstler, Curtis; Abrahamson, Tim; Barrere, Wm. Gerrit; Cohen, Amy; Keilman, George; Oliver, Leonard R.; Peskin, Natalya, Catheter with multiple ultrasound radiating members.
  17. Wilson, Richard R.; Wilcox, Robert L.; Genstler, Curtis; Abrahamson, Tim; Barrere, Wm. Gerrit; Cohen, Amy; Keilman, George; Oliver, Leonard R.; Peskin, Natalya, Catheter with multiple ultrasound radiating members.
  18. Wilson, Richard R.; Wilcox, Robert L.; Genstler, Curtis; Abrahamson, Tim; Barrere, Wm. Gerrit; Cohen, Amy; Keilman, George; Oliver, Leonard R.; Peskin, Natalya, Catheter with multiple ultrasound radiating members.
  19. Wilson, Richard R.; Wilcox, Robert L.; Genstler, Curtis; Abrahamson, Tim; Barrere, Wm. Gerrit; Cohen, Amy; Keilman, George; Oliver, Leonard R.; Peskin, Natalya, Catheter with multiple ultrasound radiating members.
  20. Stewart, Duncan John, Cell based therapy for the pulmonary system.
  21. Duncan J. Stewart CA, Cell-based gene therapy for the pulmonary system.
  22. Stewart, Duncan John, Cell-based therapy for the pulmonary system.
  23. Michal, Eugene T.; Basu, Shubhayu; Sheehy, Alexander J.; Spinale, Francis G.; Mukherjee, Rupak, Composition for modifying myocardial infarction expansion.
  24. Isner, Jeffrey M.; Asahara, Takayuki, Compositions and methods for modulating vascularization.
  25. Leonhardt, Howard J; Lashinski, Robert D, Deployment system for myocardial cellular material.
  26. Leonhardt, Howard J; Lashinski, Robert D., Deployment system for myocardial cellular material.
  27. Claude, Charles D.; Kawula, Paul J.; Hossainy, Syed Faiyaz Ahmed; Tran, Kimchi, Device and method for combining a treatment agent and a gel.
  28. Claude, Charles D.; Kawula, Paul J.; Hossainy, Syed Faiyaz Ahmed; Tran, Kimchi, Device and method for combining a treatment agent and a gel.
  29. Claude, Charles D.; Kawula, Paul J.; Hossainy, Syed Faiyaz Ahmed; Tran, Kimchi, Device and method for combining a treatment agent and a gel.
  30. Claude,Charles D.; Kawula,Paul J.; Hossainy,Syed Faiyaz Ahmed; Tran,Kimchi, Device and method for combining a treatment agent and a gel.
  31. Glines, Robert C.; Weller, Gary B., Device and methods for the delivery and injection of therapeutic and diagnostic agents to a target site within a body.
  32. Chee, U. Hiram; Meuller, Richard, Devices and methods for delivering a drug.
  33. Zhu, Qingsheng; Ortega, Daniel Felipe, Devices and methods for steering electrical stimulation in cardiac rhythm management.
  34. Zhu, Qingsheng; Ortega, Daniel Felipe, Devices and methods for steering electrical stimulation in cardiac rhythm management.
  35. Mandrusov,Evgenia; Consigny,Paul; Salo,Rodney W., Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure.
  36. Zhu, Qingsheng; Ortega, Daniel Felipe; Spinelli, Julio Cesar, Devices, methods, and systems including cardiac pacing.
  37. Raghu Raghavan ; Raju R. Viswanathan ; Timothy Poston SG, Drug delivery and catheter systems, apparatus and processes.
  38. Flugelman, Moshe, Drug-eluting intravascular prostheses and methods of use.
  39. Zhu, Qingsheng; Ortega, Daniel Felipe, Endocardial pacing devices and methods useful for resynchronization and defibrillation.
  40. Zhu, Qingsheng; Ortega, Daniel Felipe, Endocardial pacing devices and methods useful for resynchronization and defibrillation.
  41. Zhu, Qingsheng; Ortega, Daniel Felipe, Endocardial pacing relating to conduction abnormalities.
  42. Zhou, Mingdong, Extended release of neuregulin for treating heart failure.
  43. Stankus, John J.; Michal, Eugene; Trollsas, Mikael; Katz, Brandon; Basu, Shubhayu, High-viscosity hyaluronic acid compositions to treat myocardial conditions.
  44. Liu, Lili; Westlund, Randy; Girouard, Steven D., His bundle mapping, pacing, and injection lead.
  45. Maskara, Barun; Ding, Jiang; Arcot-Krishnamurthy, Shantha; Shuros, Allan C., His capture verification using electro-mechanical delay.
  46. Dong, Yanting; Shuros, Allan C.; Ding, Jiang; Meyer, Scott A.; Shome, Shibaji, His-bundle capture verification and monitoring.
  47. Claude, Charles; Kwok, Connie; Michal, Gene; Qu, Jihong; Liao, Sophia, Hydrogel bioscaffoldings and biomedical device coatings.
  48. Michal, Eugene T., Hydrogel bioscaffoldings and biomedical device coatings.
  49. Tilson, Alexander Q.; Dreyer, Paul J.; Barham, Mitchell C.; Scheeff, Mark C.; Love, Charles S.; Gomes, Garrett J.; Kurniawan, Jonathan, Inflatable medical devices.
  50. Mirzaee Daryush, Local drug delivery injection catheter.
  51. Mirzaee, Daryush, Local drug delivery injection catheter.
  52. Naimark, Wendy; Palasis, Maria; Herrmann, Robbert A, Medical device for delivery of a biologically active material to a lumen.
  53. Hansmann, Douglas R.; Wilcox, Robert L.; Rule, Peter R.; Villar, Francisco S., Method and apparatus for detecting vascular conditions with a catheter.
  54. Mueller, Richard L.; Chee, U. Hiram, Method and apparatus for recurrent demand injury in stimulating angiogenesis.
  55. Mueller, Richard L.; Chee, U. Hiram; Kermode, James R., Method and apparatus for treating ischemic tissue.
  56. Chee,U. Hiram; Mueller,Richard L.; Kermode,James R.; Tom,Curtis P.; Murphy Chutorian,Douglas, Method and apparatus for treatment of atrial fibrillation.
  57. Mueller, Richard L.; Chee, U. Hiram, Method and devices for heart treatment.
  58. Vigil, Dennis M.; Reiss, Robert E.; Barath, Peter, Method for delivering medication into an arterial wall for prevention of restenosis.
  59. Vigil, Dennis M.; Reiss, Robert E.; Barath, Peter, Method for delivering medication into an arterial wall for prevention of restenosis.
  60. Zhou, Mingdong, Method for inhibiting cell growth using anti-ErbB-3 and anti-ErbB-2 antibodies.
  61. Mandrusov, Evgenia; Michal, Eugene T., Method for intravascular delivery of a treatment agent beyond a blood vessel wall.
  62. Mueller,Richard L.; Chee,U. Hiram, Method for treating a patient at risk of loss of cardiac function by cardiac ischemia.
  63. Crystal Ronald G. ; Rosengart Todd K., Method of inducing angiogenesis.
  64. Whitehouse,Martha J.; Kavanaugh,W. Michael, Method of treating coronary artery disease by administering FGF-4.
  65. Whitehouse, Martha J.; Kavanaugh, W. Michael, Method of treating coronary artery disease by administering FGF-5.
  66. Whitehouse, Martha J.; Kavanaugh, W. Michael, Method of treating coronary artery disease by administering FGF-9.
  67. Zhang, H. Steve; Zhang, Lei, Methods and compositions for modulating cardiac contractility.
  68. Ma, Yue, Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof.
  69. Lue,Tom F.; Lin,Ching Shwun; Kan,Yuet W., Methods and compositions for preventing and treating male erectile dysfunction.
  70. Lue, Tom F.; Lin, Ching-Shwun; Kan, Yuet W., Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder.
  71. Lue,Tom F.; Lin,Ching Shwun; Kan,Yuet W.; Carroll,Peter, Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder.
  72. Whitehouse, Martha Jo, Methods and compositions for the treatment of peripheral artery disease.
  73. Whitehouse,Martha Jo, Methods and compositions for the treatment of peripheral artery disease.
  74. Lue,Tom F.; Lin,Ching Shwun; Kan,Yuet W.; Carroll,Peter, Methods and compositions for treating male erectile dysfunction.
  75. Zhu, Dexu; Muramatsu, Mitsumi; Xie, Jianshu; Ni, Cheng; Wang, Ming-Wei, Methods and compositions for treating or preventing bacterial infection.
  76. Basu, Shubhayu; Chan, Gregory Waimong, Methods and compositions for treating post-cardial infarction damage.
  77. Basu, Shubhayu; Chan, Gregory Waimong; Min, Sungwoo, Methods and compositions for treating post-cardial infarction damage.
  78. Michal, Eugene; Basu, Shubhayu; Kuo, Hai-Chien, Methods and compositions for treating post-myocardial infarction damage.
  79. Michal, Eugene; Basu, Shubhayu; Kuo, Hai-Chien, Methods and compositions for treating post-myocardial infarction damage.
  80. Hossainy, Syed; Ngo, Michael; Trollsas, Mikael; Stankus, John; Michal, Gene, Methods and compositions for treating tissue using silk proteins.
  81. Hossainy, Syed; Ngo, Michael; Trollsas, Mikael; Stankus, John; Michal, Gene, Methods and compositions for treating tissue using silk proteins.
  82. Hossainy, Syed; Ngo, Michael; Trollsas, Mikael; Stankus, John; Michal, Gene, Methods and compositions for treating tissue using silk proteins.
  83. Hossainy, Syed; Ngo, Michael; Trollsas, Mikael; Stankus, John; Michal, Gene, Methods and compositions for treating tissue using silk proteins.
  84. Michal, Eugene T.; Mandrusov, Evgenia; Claude, Charles D.; Ding, Nadine; Simhambhatla, Murthy; Hossainy, Syed Faiyez Ahmed; Sridharan, Srinivasan; Consigny, Paul, Methods and compositions to treat myocardial conditions.
  85. Michal, Eugene T.; Mandrusov, Evgenia; Claude, Charles D.; Ding, Ni; Simhambhatla, Murthy; Hossainy, Syed Faiyaz Ahmed; Sridharan, Srinivasan; Consigny, Paul, Methods and compositions to treat myocardial conditions.
  86. Michal, Eugene T.; Mandrusov, Evgenia; Claude, Charles D.; Ding, Ni; Simhambhatla, Murthy; Hossainy, Syed Faiyez Ahmed; Sridharan, Srinivasan; Consigny, Paul, Methods and compositions to treat myocardial conditions.
  87. Michal, Eugene T.; Mandrusov, Evgenia; Claude, Charles D.; Ding, Ni; Simhambhatla, Murthy; Hossainy, Syed Faiyez Ahmed; Sridharan, Srinivasan; Consigny, Paul, Methods and compositions to treat myocardial conditions.
  88. Michal, Eugene T.; Ross, Jeffrey, Methods and compositions to treat myocardial conditions.
  89. Michal,Eugene T.; Ross,Jeffrey, Methods and compositions to treat myocardial conditions.
  90. Ortega, Daniel Felipe; Giniger, Alberto German, Methods for treating the physiological electric conduction of the heart.
  91. Flugelman, Moshe, Methods of hemodialysis utilizing grafts coated with cells expressing human fibulin-5.
  92. Michal, Eugene T.; Basu, Shubhayu; Sheehy, Alexander J.; Spinale, Francis G.; Mukherjee, Rupak, Methods of modifying myocardial infarction expansion.
  93. Chee, U. Hiram; Mueller, Richard L.; Kermode, James R.; Tom, Curtis P.; Murphy-Chutorian, Douglas, Methods of treating cardiac arrhythmia.
  94. Zhu, Qingsheng; Ortega, Daniel Felipe, Methods, devices and systems for cardiac rhythm management using an electrode arrangement.
  95. Zhu, Qingsheng; Ortega, Daniel Felipe, Methods, devices and systems for cardiac rhythm management using an electrode arrangement.
  96. Zhu, Qingsheng; Ortega, Daniel Felipe; Spinelli, Julio Cesar, Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device.
  97. Zhu, Qingsheng; Ortega, Daniel Felipe; Spinelli, Julio César, Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device.
  98. Michal, Eugene; Trollsas, Olof Mikael; Basu, Shubhayu, Modified two-component gelation systems, methods of use and methods of manufacture.
  99. Michal, Eugene; Trollsas, Olof Mikael; Basu, Shubhayu, Modified two-component gelation systems, methods of use and methods of manufacture.
  100. Michal, Eugene; Trollsas, Olof Mikael; Basu, Shubhayu, Modified two-component gelation systems, methods of use and methods of manufacture.
  101. Michal, Gene; Basu, Shubhayu, Modified two-component gelation systems, methods of use and methods of manufacture.
  102. Whitehurst, Todd K.; Thacker, James R.; McGivern, James P.; McClure, Kelly H., Neurostimulation and coronary artery disease treatment.
  103. Ortega, Daniel Felipe; Giniger, Alberto German, Pacemaker which reestablishes or keeps the physiological electric conduction of the heart and a method of application.
  104. Cantor, Thomas L., Parathyroid hormone antagonists and uses thereof.
  105. Mueller,Richard L.; Chee,U. Hiram, Photoatherolytic catheter apparatus and method.
  106. Tom, Curtis P., Pressure sensor for therapeutic delivery device and method.
  107. Tom,Curtis P., Pressure sensor for therapeutic delivery device and method.
  108. Hossainy, Syed; Ludwig, Florian Niklas; Pacetti, Stephen; Consigny, Paul; El-Nounou, Fozan; Glauser, Thierry; DesNoyer, Jessica, Pro-healing agent formulation compositions, methods and treatments.
  109. Yuan, Chong Sheng, Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof.
  110. Yuan, Chong-Sheng, Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof.
  111. Yuan,Chong Sheng, Reversible inhibitors of SAH hydrolase and uses thereof.
  112. Zhang, John; Lichttenegger, Gary; Rodriguey, James E.; Tachibana, Katsuro, Sheath for use with an ultrasound element.
  113. Zhang, John; Lichttenegger, Gary; Rodriguey, James E.; Tachibana, Katsuro, Sheath for use with an ultrasound element.
  114. Zhang,John; Lichttenegger,Gary; Rodriguey,James E.; Tachibana,Katsuro, Sheath for use with an ultrasound element.
  115. Shanley,John F., Stent wall structure.
  116. Shanley,John F., Stent wall structure.
  117. Pinaki Ray ; Vinayak D. Bhat ; Daryush Mirzaee, Substance delivery apparatus and a method of delivering a therapeutic substance to an anatomical passageway.
  118. Ray,Pinaki; Bhat,Vinayak D.; Mirzaee,Daryush, Substance delivery apparatus and a method of delivering a therapeutic substance to an anatomical passageway.
  119. Nash, John E.; Evans, Douglas G.; Hoganson, David M., Systems and methods for delivering agents into targeted tissue of a living being.
  120. Nash, John E.; Evans, Douglas G.; Hoganson, David M., Systems and methods for delivering agents into targeted tissue of a living being.
  121. Nash,John E.; Evans,Douglas G.; Hoganson,David M., Systems and methods for delivering agents into targeted tissue of a living being.
  122. Beyerlein, Dagmar, Systems and methods for detecting tissue contact and needle penetration depth.
  123. Beyerlein,Dagmar, Systems and methods for detecting tissue contact and needle penetration depth.
  124. Beyerlein, Dagmar, Systems and methods for detecting tissue contact and needle penetration depth using static fluid pressure measurements.
  125. Zhu, Qingsheng; Ortega, Daniel Felipe, Systems, devices and methods for monitoring efficiency of pacing.
  126. Zhu, Qingsheng; Ortega, Daniel Felipe, Systems, devices and methods for monitoring efficiency of pacing.
  127. Mandrusov, Evgenia; Claude, Charles; Michal, Eugene T., Tissue regeneration.
  128. Gholam A. Peyman, Treatment of anoxic tissue with angiogenesis-inducing implants.
  129. Schreiner,George F.; Johnson,Richard J., Treatment of eclampsia and preeclampsia.
  130. Schreiner, George F.; Johnson, Richard J., Treatment of microvascular angiopathies.
  131. Keilman, George; Hansmann, Douglas R.; Soltani, Azita; Wilson, Richard R., Ultrasonic catheter power control.
  132. Keilman, George; Hansmann, Douglas R.; Soltani, Azita; Wilson, Richard R., Ultrasonic catheter power control.
  133. Keilman, George; Hansmann, Douglas R.; Soltani, Azita; Wilson, Richard R., Ultrasonic catheter power control.
  134. Wilson, Richard R., Ultrasonic catheter with axial energy field.
  135. Bennett, Frederick J.; Rodriguey, James E., Ultrasound assembly with increased efficacy.
  136. Bennett, Frederick J.; Zhang, John; Lichttenegger, Gary; Rodriguey, James E.; Tachibana, Katsuro, Ultrasound catheter for providing a therapeutic effect to a vessel of a body.
  137. Bennett,Frederick J.; Zhang,John; Lichttenegger,Gary; Rodriguey,James E.; Tachibana,Katsuro, Ultrasound catheter with utility lumen.
  138. Wilson, Richard R., Ultrasound radiating members for catheter.
  139. Yuan, Chong-Sheng, Use of reversible inhibitors of S-adenosyl-L-homocysteine hydrolase for treating lupus.
  140. Flugelman, Moshe Y.; Gluzman, Zoya; Preis, Meir; Koren, Belly; Cohen, Tzafra; Tsaba, Adili; Weisz, Anat, Vascular cells genetically altered to over-express angiogenic proliferation and maturation factors; treatment of atherosclerosis using same.
  141. Flugelman, Moshe, Vectors encoding cell growth and adhesion factors for simultaneous growth and adhesion of cells.
  142. Ortega, Daniel Felipe; Giniger, Alberto German; Zhu, Qingsheng; Shapland, J. Edward, Ventricular pacing.
  143. Ortega, Daniel Felipe; Giniger, Alberto German; Zhu, Qingsheng; Shapland, J. Edward, Ventricular pacing.
  144. Roorda, Wouter, Vessel enlargement by arteriogenic factor delivery.
  145. Roorda,Wouter, Vessel enlargement by arteriogenic factor delivery.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로