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Method and article to induce hematopoietic expansion

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/28
  • A61K-009/19
  • A61K-038/18
  • C12N-005/08
출원번호 US-0070686 (1998-04-30)
발명자 / 주소
  • Jefferies Steven R.
대리인 / 주소
    Renner, Kenner, Greive, Bobak, Taylor & Weber
인용정보 피인용 횟수 : 53  인용 특허 : 19

초록

An article and method to create retrievable sites of implantable and transplantable bone marrow, in a human or animal recipient, by implanting bone-marrow inducing conjugates of collagen and demineralized freeze-dried bone allograft (DFDBA) into accessible soft or hard tissue sites is provided. The

대표청구항

[ I claim:] [1.] A bone marrow inducing conjugate composite comprising from about 10 to about 90 parts by weight of demineralized freeze-dried bone matrix (DFDBA), from about 90 to about 10 parts by weight of collagen, and one selected from the group consisting of (a) mammalian stem cells, (b) bone

이 특허에 인용된 특허 (19)

  1. Ducheyne Paul (Rosemont PA) El-Ghannam Ahmed (Philadelphia PA) Shapiro Irving (Philadelphia PA), Bioactive material template for in vitro synthesis of bone tissue.
  2. Ducheyne Paul (Rosemont PA) El-Ghannam Ahmed (Philadelphia PA) Shapiro Irving (Philadelphia PA), Bioactive material template for in vitro synthesis of bone tissue.
  3. Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Bone graft material for osseous defects and method of making same.
  4. Lawman Michael J. P. (Orlando FL) Lawman Patricia D. (Orlando FL) Denslow Nancy D. (Gainesville FL), Cells producing stem cell proliferation factor.
  5. Chen Charles C. ; Jefferies Steven R., Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof.
  6. Palsson Bernhard O. (Ann Arbor MI) Emerson Stephen G. (Ann Arbor MI) Schwartz Richard M. (Ann Arbor MI), Device for maintaining and growing human stem and/or hematopoietics cells.
  7. Tsukamoto Ann ; Baum Charles M. ; Aihara Yukoh,JPX ; Weissman Irving, Human hematopoietic stem cell.
  8. Reiner Roland (Eishborn DEX) KiBing Wolfgang (Eschwege DEX) Dring Helga (Cologne DEX) Kster-Lsche Kari (Usingen DEX) Heide Helmut (Kelkheim DEX), Implantable drug depot and process for the production thereof.
  9. Ponting Ian L. O. (Woodland Hills CA), Medium for long-term proliferation and development of cells.
  10. DiGiusto David (Palo Alto CA) Galy Anne (Palo Alto CA), Method for producing a highly enriched population of hematopoietic stem cells.
  11. Schwartz Richard Merrill ; Tucker Sean Newton ; Chary Srikanth Ranga ; Kuo Suzanne Chang, Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein.
  12. Ammann Arthur J. (San Rafael CA) Rudman Christopher G. (San Francisco CA), Method of inducing bone growth using TGF-b 상세보기
  • Jefferies Steven R. (5802 Leith Walk Baltimore MD 21239), Method of inducing osseous formation by implanting bone graft material.
  • Rosenthal Gary J. (Boulder CO) Gerber Michael J. (Denver CO), Method of stimulating hematopoiesis with hemoglobin.
  • Fei Rui G. (Seattle WA) Heimfeld Shelly (Woodinville WA) Minshall Billy W. (Mill Creek WA) Berenson Ronald J. (Mercer Island WA), Methods and device for culturing human hematopoietic cells and their precursors.
  • Emerson Stephen G. (Ann Arbor MI) Clarke Michael F. (Ann Arbor MI) Palsson Bernhard O. (Ann Arbor MI), Methods, compositions and devices for growing human hematopoietic cells.
  • Rodan Gideon A. (Bryn Mawr PA) Jacobs John W. (Irvine CA) Sardana Mohinder K. (Lansdale PA) Gazit Dan (Jerusalem ILX) Chorev Michael (Jerusalem ILX) Muhlrad Andras (Jerusalem ITX) Shteyer Arye (Jerus, Osteogenic growth polypeptides identified from regenerating bone marrow.
  • Bentz Hanne (Newark CA) Thompson Andrea Y. (Mountain View CA) Armstrong Rosa (Palo Alto CA) Rosen David M. (San Jose CA), Use of bone morphogenetic protein in synergistic combination with TGF-b 상세보기
  • Namen Anthony E. ; Goodwin Raymond G. ; Lupton Stephen D. ; Mochizuki Diane Y., Use of interleukin-7 to stimulate proliferation of hematopoietic cell precursors.
  • 이 특허를 인용한 특허 (53)

    1. Kadiyala, Sudhakar; Bruder, Scott, Autologous bone graft material.
    2. Mohan, Suneeth Elizabeth; Shimko, Daniel Andrew, Bone filler material.
    3. Cole, Jantzen; Smith, Timothy, Bone graft substitute composition.
    4. Cole, Jantzen; Smith, Timothy, Bone graft substitute composition.
    5. Cole,Jantzen; Smith,Timothy, Bone graft substitute composition.
    6. Miller, Leasa C.; Richelsoph, Kelly Coupe; Moseley, Jon P., Bone graft substitute composition.
    7. Miller,Leasa C.; Richelsoph,Kelly Coupe; Moseley,Jon P., Bone graft substitute composition.
    8. Petersen,Donald W., Bone graft substitute composition.
    9. Petersen,Donald W.; Blum,Barbara E., Bone graft substitute composition.
    10. Petersen,Donald W.; Haggard,Warren O.; Randolph,Donald A.; Hagan,Cary P., Bone graft substitute composition.
    11. Richelsoph, Kelly Coupe; Miller, Leasa C., Bone graft substitute composition.
    12. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
    13. Thorne, Kevin J., Bone growth particles and osteoinductive composition thereof.
    14. Akella, Rama; Garrett, Ian Ross; Wen, Hai Bo; Li, Shuliang; Acker, Dean M.; Wilhelm, Nichole, Bone void fillers.
    15. Kadiyala, Sudhakar; Bruder, Scott P., Cell-containing bone graft material.
    16. Moseley, Jon P.; Carroll, Michael E.; McCanless, Jonathan D., Composite bone graft substitute cement and articles produced therefrom.
    17. Moseley, Jon P.; Carroll, Michael E.; McCanless, Jonathan D., Composite bone graft substitute cement and articles produced therefrom.
    18. Moseley, Jon P.; Carroll, Michael E.; McCanless, Jonathan D., Composite bone graft substitute cement and articles produced therefrom.
    19. Moseley, Jon P.; Carroll, Michael E.; McCanless, Jonathan D.; Schulz, Olaf; Fronk, Andy, Composite bone graft substitute cement and articles produced therefrom.
    20. Moseley, Jon P.; Carroll, Michael E.; McCanless, Jonathan D.; Schulz, Olaf; Fronk, Andy, Composite bone graft substitute cement and articles produced therefrom.
    21. Thorne, Kevin J., Composition and process for bone growth and repair.
    22. Masinaei, Leila; Wolfinbarger, Jr., Lloyd, Compositions for repair of defects in osseous tissues, and methods of making the same.
    23. Gross, Jeffrey M.; Peckham, Steve; Scifert, Jeffrey L.; Badura, Jeffrey; Scarborough, Nelson; Vickers, Scott, Compositions for treating bone defects.
    24. Gross, Jeffrey M.; Peckham, Steve; Scifert, Jeffrey; Badura, Jeffrey; Scarborough, Nelson; Vickers, Scott, Compositions for treating bone defects.
    25. Drapeau, Susan J.; Chamness, Kathy L.; McKay, William F., Demineralized bone matrix devices.
    26. Lauritzen, Nels; Shimp, Lawrence A.; Mitchell, Brent, Fenestrated wound repair scaffold.
    27. Lauritzen, Nels; Shimp, Lawrence A.; Mitchell, Brent, Foam-formed collagen strand.
    28. Lauritzen, Nels; Shimp, Lawrence A.; Mitchell, Brent S., Foam-formed collagen strand.
    29. Wolfinbarger, Jr.,Lloyd; Qin,XiaoFei, In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby.
    30. Wolfinbarger, Lloyd; Qin, Xiaofei, In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby.
    31. Fort, James J.; Krill, Steven L.; Law, Devalina; Qiu, Yihong; Schmitt, Eric A., Inhibitors of crystallization in a solid dispersion.
    32. Cole,Jantzen A.; Carroll,Michael E.; Moseley,Jon P.; Richelsoph,Kelly C., Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects.
    33. Drapeau, Susan J.; Chamness, Kathy L.; McKay, William F., Malleable implants containing demineralized bone matrix.
    34. Drapeau, Susan J.; Chamness, Kathy L.; McKay, William F., Malleable implants containing demineralized bone matrix.
    35. Drapeau, Susan J.; Remsen, Kathy L.; McKay, William F.; Scarborough, Nelson L., Malleable implants containing demineralized bone matrix.
    36. Drapeau, Susan J; Remsen, Kathy L; McKay, William F, Malleable implants containing demineralized bone matrix.
    37. Drapeau, Susan J; Remsen, Kathy L; McKay, William F; Scarborough, Nelson L, Malleable implants containing demineralized bone matrix.
    38. McKay, William F.; Scifert, Jeffrey L.; Remsen, Kathy L.; Billy, Didier; Gillissen, Mirian; Vickers, Scott M., Malleable multi-component implants and materials therefor.
    39. McKay, William F.; Scifert, Jeffrey L.; Remsen, Kathy; Billy, Didier; Gillissen, Mirian; Vickers, Scott M., Malleable multi-component implants and materials therefor.
    40. Livesey, Stephen Anthony; Traianedes, Kathy, Method of inducing cellular growth and materials for use therewith.
    41. Lauritzen, Nels J.; Shimp, Lawrence A., Methods for collagen processing and products using processed collagen.
    42. Berndl, Gunther; Breitenbach, Jörg; Heger, Robert; Stadler, Michael; Wilke, Peter; Rosenberg, Jörg, Self-emulsifying active substance formulation and use of this formulation.
    43. Berndl, Gunther; Breitenbach, Jörg; Heger, Robert; Stadler, Michael; Wilke, Peter; Rosenberg, Jörg, Self-emulsifying active substance formulation and use of this formulation.
    44. Fort,James J.; Krill,Steven L.; Law,Devalina; Qiu,Yihong; Porter,William R.; Schmitt,Eric A., Solid dispersion pharamaceutical formulations.
    45. Berndl, Gunther; Rosenberg, Joerg; Liepold, Bernd; Breitenbach, Joerg; Reinhold, Ulrich; Alani, Laman; Ghosh, Soumojeet, Solid pharmaceutical dosage form.
    46. Rosenberg, Jeorg; Reinhold, Ulrich; Liepold, Bernd; Berndl, Gunther; Breitenbach, Joerg; Alani, Laman; Ghosh, Soumojeet, Solid pharmaceutical dosage form.
    47. Rosenberg, Joerg; Reinhold, Ulrich; Liepold, Bernd; Berndl, Gunther; Breitenbach, Joerg; Alani, Laman; Ghosh, Soumojeet, Solid pharmaceutical dosage form.
    48. Rosenberg, Joerg; Reinhold, Ulrich; Liepold, Bernd; Berndl, Gunther; Breitenbach, Joerg; Alani, Laman; Ghosh, Soumojeet, Solid pharmaceutical dosage form.
    49. Rosenberg, Joerg; Reinhold, Ulrich; Liepold, Bernd; Berndl, Gunther; Breitenbach, Joerg; Alani, Laman; Ghosh, Soumojeet, Solid pharmaceutical dosage form.
    50. Rosenberg, Joerg; Reinhold, Ulrich; Liepold, Bernd; Berndl, Gunther; Breitenbach, Joerg; Alani, Laman; Ghosh, Soumojeet, Solid pharmaceutical dosage form.
    51. Rosenberg, Jöerg; Reinhold, Ulrich; Liepold, Bernd; Berndl, Gunther; Breitenbach, Jörg; Alani, Laman L.; Ghosh, Soumojeet, Solid pharmaceutical dosage formulation.
    52. Overby,Robyn J.; Schulz,Olaf H.; Burgess,Ann V.; Haggard,Warren O.; Vincent,Michael, Synthetic bone substitute material.
    53. Overby, Robyn J.; Schulz, Olaf H.; Burgess, Ann V.; Haggard, Warren O.; Vincent, Michael, Synthetic, malleable bone graft substitute material.

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